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DNA methylation can provide effective markers for major cancers, study reveals

In a new study, published online in the July 26 issue of PNAS, researchers at University of California San Diego School of Medicine, with colleagues in Xijing Hospital and Sun Yat-sen Cancer Center in China, report that DNA methylation can provide effective markers for at least four major cancers, not only correctly differentiating malignant tissues from normal, but also providing information on prognosis and survival.

28 Jun 2017

Clinical trial of immunotherapy shows promising results for patients with melanoma brain tumors

Two years ago, when Kathy Roberts was 54, she started having pain in her ankle. She ignored it. Then it became swollen, and she had more and more trouble walking. So she went to a series of doctors trying to figure out the problem.

27 Jun 2017

Study shows link between metabolic syndrome and risk of cognitive disorders

A study presented at the European Academy of Neurology Congress in Amsterdam has shown that obesity alone is not a risk factor for cognitive disorders, but commonly associated co-morbidities such as diabetes, high blood pressure and metabolic disorders are.

27 Jun 2017

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Discovered more than two decades ago, the hormone leptin has been widely hailed as the key regulator of leanness. Yet, the pivotal experiments that probe the function of this protein and unravel the precise mechanism of its action as a guardian against obesity are largely missing.

24 Jun 2017

Study offers insight into earliest molecular steps that lead to organ rejection

Researchers at the University of Pittsburgh School of Medicine and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ.

23 Jun 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Abbott introduces Sekisui CP3000 fully automated coagulation system for accurate test results

Today, Abbott announced that the Sekisui CP3000 coagulation system, a fully automated analyzer that tests bleeding and clotting function in blood, is now available in Europe, the Middle East, and Asia Pacific.

23 Jun 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

Excess male hormones in PCOS women contribute to metabolic complications, study shows

Scientists from the University of Birmingham have discovered the link between increased male hormones and metabolic complications such as diabetes and fatty liver disease in patients with polycystic ovary syndrome.

23 Jun 2017

ISU entomologist urges summertime precautions against mosquitoes and ticks

Ryan Smith, an assistant professor of entomology at Iowa State University is encouraging Iowans to take precautions this summer when spending time outdoors in areas commonly populated by mosquitoes and ticks, which can transmit West Nile virus and other diseases that can have serious or potentially fatal outcomes.

22 Jun 2017

Popular prostate drug has negative impact on men's overall health, study suggests

Treatment of benign prostatic hyperplasia (BPH) with the commonly prescribed Avodart (Dutsteride) may put men at an increased risk for diabetes, elevated cholesterol levels, non-alcoholic fatty liver disease (NAFLD) and worsening erectile dysfunction.

22 Jun 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

UCLA-led study reveals possibility of CMV and HIV transmission from mothers to infants

HIV-positive women with cytomegalovirus, or CMV, in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV, the virus that causes AIDS, to their infants, according to a UCLA-led study.

22 Jun 2017

Scientists uncover vital clues in puzzle over pre-eclampsia and increased risk of heart disease

Scientists studying a mystery link between the dangerous pregnancy complication pre-eclampsia and an increased risk of heart disease in later life for both mother and child have uncovered important new clues.

21 Jun 2017

Could a blood test predict how cancer spreads in children?

Traditionally, we use biopsies to try to predict how cancer spreads. There are a number of molecular markers that are used, but biopsy is a limited approach. Now, the current trend is to use liquid biopsy, which is basically a blood sample.

21 Jun 2017

Steaming freshwater fish reduces presence of cyanotoxins, study shows

A group of researchers from the Area of Toxicology in the Department of Nutrition and Bromatology. Toxicology and Legal Medicine at the University of Seville has published a globally pioneering study that shows that steaming freshwater fish for more than two minutes reduces the presence of cylindrospermopsin, a cyanotoxin, by up to 26%. However, if boiled, the reduction is smaller, 18%, with the corresponding increase in risk for the consumer.

20 Jun 2017

Japanese scientists develop method to isolate anti-Alzheimer's compounds from plants

Japanese scientists have developed a method to isolate and identify active compounds in plant medicines, which accurately accounts for drug behavior in the body.

20 Jun 2017

Study finds vaccine to lower cholesterol levels could also immunize against heart disease

In people with high cholesterol levels, the fat that is built up in the artery walls narrows the arteries causing a condition called atherosclerosis. A study published on 19th June in the European Heart Journal has found the likelihood of a vaccine that can immunize humans having atherosclerosis, subsequent to successful outcomes in a mouse model study. At present, phase I clinical trial has begun in patients to see the possibility of translating the study findings to humans.

20 Jun 2017

Study finds direct link between birth outcomes and placental oxygen transport

When a baby is born small, it's often attributed to genetic factors or maternal risk factors like poor nutrition or smoking.

16 Jun 2017

Broccoli may help type 2 diabetes patients manage their blood sugar, study finds

According to a new study, concentrated broccoli sprout extract may help type 2 diabetes patients manage their blood sugar.

16 Jun 2017

Liver News and Research

DNA methylation can provide effective markers for major cancers, study reveals

Clinical trial of immunotherapy shows promising results for patients with melanoma brain tumors

Study shows link between metabolic syndrome and risk of cognitive disorders

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Study offers insight into earliest molecular steps that lead to organ rejection

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

Abbott introduces Sekisui CP3000 fully automated coagulation system for accurate test results

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Excess male hormones in PCOS women contribute to metabolic complications, study shows

ISU entomologist urges summertime precautions against mosquitoes and ticks

Popular prostate drug has negative impact on men's overall health, study suggests

Could the mTOR pathway be used to protect against cancer?

UCLA-led study reveals possibility of CMV and HIV transmission from mothers to infants

Scientists uncover vital clues in puzzle over pre-eclampsia and increased risk of heart disease

Could a blood test predict how cancer spreads in children?

Steaming freshwater fish reduces presence of cyanotoxins, study shows

Japanese scientists develop method to isolate anti-Alzheimer's compounds from plants

Study finds vaccine to lower cholesterol levels could also immunize against heart disease

Study finds direct link between birth outcomes and placental oxygen transport

Broccoli may help type 2 diabetes patients manage their blood sugar, study finds

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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