Clinical Trial News and Research

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Cheaper drug equally effective in preserving cardiovascular function in boys with DMD

A new clinical trial conducted at The Ohio State University Wexner Medical Center found a cost-effective generic medication works just as well as a more expensive drug in preserving cardiovascular function in boys with Duchenne muscular dystrophy (DMD).

24 Sep 2019

$Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus$

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Researchers from the University of California San Francisco and Veterans Affairs Health Care System, San Francisco investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients.

24 Sep 2019

Vitamin D and fish oil show promise to protect against cancer mortality and heart attacks

The VITamin D and OmegA-3 Trial (VITAL) is the largest and most recent to test whether vitamin D or fish oil can effectively prevent cancer or cardiovascular disease.

24 Sep 2019

Research: Protein complex represents a new metabolic target for liver cancer

Disrupting a metabolic pathway in the liver in a way that creates a more "cancer-like" metabolism actually reduces tumor formation in a mouse model of liver cancer.

24 Sep 2019

Obese, pregnant women may not require extra calories, shows study

The Institute of Medicine's guidelines currently advise all pregnant women to increase calorie intake by 340-450 calories/day during their second and third trimesters, regardless of their body size at conception.

24 Sep 2019

Electric baseball cap may help to reverse male pattern balding

Researchers have developed an electric patch that stimulates hair growth to help reverse male balding. The patch has now been embedded in a baseball cap.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

New clinical trial tests immunotherapy drug for prostate cancer patients on active surveillance

Stephenson Cancer Center Testing Drug for Prostate Cancer Patients on Active Surveillance OKLAHOMA CITY - Men who are diagnosed with low-risk prostate cancer usually opt for active surveillance - a monitoring of their cancer over time without undergoing treatments that would cause side effects.

20 Sep 2019

C-Path and NORD launch new platform to accelerate drug development for rare diseases

The Critical Path Institute and the National Organization for Rare Disorders® launched the Rare Disease Cures Accelerator-Data and Analytics Platform in Rockville, MD on Tuesday, Sept. 17.

20 Sep 2019

Novel gene therapy for glycogen storage disease shows positive results

At the Association for Glycogen Storage Disease's 41st Annual Conference, Dr. David Weinstein of UConn School of Medicine and Connecticut Children's presented his groundbreaking, one-year clinical trial results for the novel gene therapy treatment for glycogen storage disease.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Whole-brain radiotherapy recommended for patients with brain metastases

Patients with brain metastases who received whole-brain radiotherapy that avoided memory-specific hippocampal neural stem cells experienced preserved cognitive function and reported fewer neurologic symptoms and better cognition over time, according to results from an NRG Oncology clinical trial presented Sept. 15, 2019 at the American Society for Radiation Oncology Annual Meeting in Chicago.

20 Sep 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Getting new therapy to patients can be harder than putting a lander on Mars

Getting new medical treatments from the lab benchtop to patients' bedsides can be harder and more expensive than putting a lander on Mars. But it doesn't have to be, says Tiffany Wilson, who heads a nonprofit organization that guides new medical solutions from the lab bench to the bedside.

19 Sep 2019

Prilenia's lead compound selected to participate in first-ever ALS platform trial

Prilenia, a newly formed biotech company focused on developing novel treatments for neurodegenerative and neurodevelopmental disorders, announces that Pridopidine, its lead compound, has been selected as the first of three potential new treatments to be included in the launch of the first ever platform trial in amyotrophic lateral sclerosis (ALS).

19 Sep 2019

New device uses electromagnetic waves to reverse Alzheimer’s

A new study, to be published in the September 3, 2019, issue of the Journal of Alzheimer's Disease, provides something to cheer about for the estimated 44 million patients who have Alzheimer’s disease (AD) in the US, and their hard-pressed caregivers.

18 Sep 2019

Cannabidiol may alleviate seizures and normalize brain rhythms in Angelman syndrome

A marijuana plant extract, also known as cannabidiol, is being commonly used to improve anxiety, sleep problems, pain, and many other neurological conditions.

18 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Treating non-Hodgkin's lymphoma patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

18 Sep 2019

Exercise may delay brain deterioration in people at high risk for Alzheimer's

Exercising several times a week may delay brain deterioration in people at high risk for Alzheimer's disease, according to a study that scientists say merits further research to establish whether fitness can affect the progression of dementia.

18 Sep 2019

Clinical Trial News and Research

Cheaper drug equally effective in preserving cardiovascular function in boys with DMD

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Vitamin D and fish oil show promise to protect against cancer mortality and heart attacks

Research: Protein complex represents a new metabolic target for liver cancer

Obese, pregnant women may not require extra calories, shows study

Electric baseball cap may help to reverse male pattern balding

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

New clinical trial tests immunotherapy drug for prostate cancer patients on active surveillance

C-Path and NORD launch new platform to accelerate drug development for rare diseases

Novel gene therapy for glycogen storage disease shows positive results

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Whole-brain radiotherapy recommended for patients with brain metastases

Researchers discover how cancer cells can trigger chronic muscle wasting condition

Getting new therapy to patients can be harder than putting a lander on Mars

Prilenia's lead compound selected to participate in first-ever ALS platform trial

New device uses electromagnetic waves to reverse Alzheimer’s

Cannabidiol may alleviate seizures and normalize brain rhythms in Angelman syndrome

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Exercise may delay brain deterioration in people at high risk for Alzheimer's

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