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Researchers reveal potential of multivalent antibodies for HIV prevention, treatment and cure

The ability of HIV to mutate has been a major challenge to vaccine development. As the body produces antibodies to target the outer HIV envelope protein, this protein changes, thwarting the circulating antibodies' ability to neutralize it.

18 Jan 2018

Findings reveal conventional cancer therapy as double-edged sword

Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

18 Jan 2018

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin.

18 Jan 2018

Researchers find new way to halt growth of breast cancer cells

An international team of researchers led from Karolinska Institutet and Science for Life Laboratory in Sweden have found a new way of halting the growth of breast cancer cells.

18 Jan 2018

A new strategy proposed for drug discovery

A joint industry/academia study of a cancer target protein reveals unusual relation between binding site flexibility and drug-target lifetime.

17 Jan 2018

Cocaine de-addiction breakthrough shows promise

Researchers have successfully created a way by which cocaine craving could be reduced. This could help in the de-addiction of thousands of users feel experts. The team of researchers neutralized a protein molecule that is commonly seen among cocaine users in their blood and brain.

16 Jan 2018

Researchers identify new anti-inflammatory drug target

A new study suggests that parmodulins may provide anti-inflammatory and anti-thrombotic protection to endothelial cells, without interfering with clotting.

16 Jan 2018

Scientists describe groundbreaking training effect on the innate immune system

"Training" of precursors of white blood cells leads to a sustained positive response of the hematopoietic system. This effect could help accelerate the formation of new white blood cells, which are vitally needed during chemotherapy, a process that can slow down hematopoiesis.

15 Jan 2018

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

Prostate tumors tend to be what scientists call "indolent" - so slow-growing and self-contained that many affected men die with prostate cancer, not of it. But for the percentage of men whose prostate tumors metastasize, the disease is invariably fatal.

15 Jan 2018

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

A combination therapy made up of two neurotrophic factors can reduce the degenerative effects of Parkinson’s disease, shows new research.

15 Jan 2018

Caltech researchers develop new method to see neural connections in living flies

The human brain is composed of billions of neurons wired together in intricate webs and communicating through electrical pulses and chemical signals.

12 Jan 2018

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Parkinson's disease is currently the second most widespread neurogenerative pathology. Current therapies are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed.

12 Jan 2018

Scarring of fat tissue in obese people can make weight loss more difficult

The fat of obese people becomes distressed, scarred and inflamed, which can make weight loss more difficult, research at the University of Exeter has found.

12 Jan 2018

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

12 Jan 2018

Study finds new mechanism regulating giant protein essential for muscle and heart function

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role in the function of skeletal muscle and the heart.

12 Jan 2018

New drug candidates may offer breakthrough in treatment of COPD

The study was a cooperative effort between the team headed by assistant professor Dr Jürgen Knobloch from the Medical Clinic III for Pneumology, Sleep and Respiratory Medicine at the Bergmannsheil University Hospital in Bochum, Germany, and Prof Dr Andrea Koch, member of the German Center for Lung Research, previously in Bochum, now at the Medical Clinic V for Pneumology at the LMU University Hospital in Munich, as well as a team from the company RespiVert Ltd, a subsidiary of Janssen Biotech Inc., and Prof Dr Erich Stoelben from the Lung Clinic in Köln-Merheim.

12 Jan 2018

UCLA scientists coax human stem cells to become sensory interneurons

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons -- the cells that give us our sense of touch.

11 Jan 2018

Circadian rhythms could hold key to novel treatments for glioblastoma

Biological clocks throughout the body play a major role in human health and performance, from sleep and energy use to how food is metabolized and even stroke severity.

10 Jan 2018

Molecule News and Research

Researchers reveal potential of multivalent antibodies for HIV prevention, treatment and cure

Findings reveal conventional cancer therapy as double-edged sword

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Researchers find new way to halt growth of breast cancer cells

A new strategy proposed for drug discovery

Cocaine de-addiction breakthrough shows promise

Researchers identify new anti-inflammatory drug target

Scientists describe groundbreaking training effect on the innate immune system

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

Caltech researchers develop new method to see neural connections in living flies

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Scarring of fat tissue in obese people can make weight loss more difficult

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Study finds new mechanism regulating giant protein essential for muscle and heart function

New drug candidates may offer breakthrough in treatment of COPD

UCLA scientists coax human stem cells to become sensory interneurons

Circadian rhythms could hold key to novel treatments for glioblastoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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