Clinical Trial News and Research

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IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

Results of the NRG Oncology clinical trial NRG-HN002 indicated that the combination of intensity-modulated radiotherapy (IMRT) and cisplatin was able to meet acceptability criteria for progression-free survival (PFS) and swallowing-related quality of life for patients who have p16-positive, non-smoking-associated oropharyngeal cancer.

18 Sep 2019

New results revealed from pilot stem cell study for stroke

Researchers led by Sean I. Savitz, MD, reported today in the journal Stem Cells that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced recovery compared to a matched historical control group.

17 Sep 2019

5 million gift will help create Edward P. Evans Center for MDS at Dana-Farber

A $5 million gift from the Edward P. Evans Foundation will create the Edward P. Evans Center for Myelodysplastic Syndromes at Dana-Farber Cancer Institute.

17 Sep 2019

Relearning to walk after stroke using a therapeutic shoe

A therapeutic shoe engineered to improve stroke recovery is proving successful and expected to hit the market by the end of the year.

17 Sep 2019

Clinical trial finds no difference in pain response between SBRT and cEBRT for patients with spinal metastases

A Phase III, NRG Oncology clinical trial that compared radiosurgery or stereotactic body radiotherapy to the conventional radiotherapy for patients with spinal metastases indicated that there was no statistically significant difference between the treatments for pain response, adverse events, FACT-G, BPI, and EQ-5D scores.

17 Sep 2019

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

Initial results of NRG Oncology Clinical Trial RTOG 9601 in men with biochemically recurrent prostate cancer receiving salvage radiotherapy demonstrated improvement in OS from the addition of long-term hormone therapy to SRT.

17 Sep 2019

Optimal AED placements may lead to better cardiac arrest outcomes

Automated external defibrillators are often placed in areas of low risk and may be unavailable during certain times of the day.

16 Sep 2019

Experts offer insights into new class of migraine medications

As research continues to show progress towards minimizing the effects of headache disorders on patients' lives, Practical Neurology gathered insights from experts in the field at The American Headache Society 61st Annual Scientific Meeting this year, where new data looking at a range of approaches from nerve stimulation to monoclonal antibodies and neuromodulation devices revealed advancements in migraine treatment.

16 Sep 2019

Heart School attendance linked to lower mortality risk in myocardial infarction patients

Patients who attend 'Heart School', as almost every patient in Sweden is invited to do after a first heart attack, live longer than non-participating patients. This is shown in a new study, by researchers at Uppsala University, published in the European Journal of Preventive Cardiology.

16 Sep 2019

Nano-sized bubbles in our body could effectively fight cancer

Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. It's your DNA that stores the important information necessary for RNA to produce proteins and make sure they act accordingly.

15 Sep 2019

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

Cancer disease incidence and severity influenced by gene mutation, tissue location

The KRAS gene is one of the commonly mutated genes in cancer. More than 40 percent of colorectal cancers have a mutated KRAS gene, or oncogene, that is at least partially responsible for cancer development.

12 Sep 2019

Electrical-first strategy for atrial fibrillation results in shorter ED length of stay

A multicenter randomized controlled clinical trial confirms that both chemical-first and electrical-first approaches are effective strategies for acute atrial fibrillation; however, an electrical-first strategy results in a significantly shorter emergency department length of stay.

12 Sep 2019

Researchers to test text-based counseling for young adults with cannabis use disorder

Researchers from the University of Tennessee, Knoxville, and Colorado State University have received a $3.2 million grant from the National Institute on Drug Abuse to test a text-delivered counseling program for young adults ages 18 to 25 with cannabis use disorder.

11 Sep 2019

Caring contacts reduce the odds of suicide attempt

A soldier named Jerome Motto received caring letters from home in World War II. They helped boost his spirits and later led to one of the nation's first successful suicide interventions.

11 Sep 2019

Two uveitis drugs perform similarly in a head-to-head clinical trial

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S.

11 Sep 2019

Study seeks to better understand, treat neuropathy in black women with breast cancer

Researchers at Indiana University School of Medicine have launched a new, unique study recruiting black women with breast cancer designed to better understand and treat neuropathy, a side effect from chemotherapy.

10 Sep 2019

KU Cancer Center awarded grant to expand reach of clinical trials to Kansas’ rural communities

The University of Kansas Cancer Center and Midwest Cancer Alliance have been awarded a grant to expand the reach of cancer clinical trials to Kansas' rural communities.

10 Sep 2019

Nurse led follow-up care helps patients with lung cancer, increases clinic efficiency

The presence of the specialist nurse within thoracic surgical centers in the United Kingdom increased clinic capacity and efficiency, reduced waiting time for appointments, promoted junior medical training and ensured continuity of care for the patients, according to an analysis reported today by Jenny Mitchell from Oxford University Hospitals NHS Foundation Trust, in Oxford, United Kingdom.

10 Sep 2019

Autoantibody test followed by CT imaging may reduce lung cancer mortality, study shows

A combination of the EarlyCDT-Lung Test followed by CT imaging in Scottish patients at risk for lung cancer resulted in a significant decrease in late stage diagnosis of lung cancer and may decrease lung cancer specific mortality, according to research presented at IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer.

10 Sep 2019

Clinical Trial News and Research

IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

New results revealed from pilot stem cell study for stroke

5 million gift will help create Edward P. Evans Center for MDS at Dana-Farber

Relearning to walk after stroke using a therapeutic shoe

Clinical trial finds no difference in pain response between SBRT and cEBRT for patients with spinal metastases

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

Optimal AED placements may lead to better cardiac arrest outcomes

Experts offer insights into new class of migraine medications

Heart School attendance linked to lower mortality risk in myocardial infarction patients

Nano-sized bubbles in our body could effectively fight cancer

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Cancer disease incidence and severity influenced by gene mutation, tissue location

Electrical-first strategy for atrial fibrillation results in shorter ED length of stay

Researchers to test text-based counseling for young adults with cannabis use disorder

Caring contacts reduce the odds of suicide attempt

Two uveitis drugs perform similarly in a head-to-head clinical trial

Study seeks to better understand, treat neuropathy in black women with breast cancer

KU Cancer Center awarded grant to expand reach of clinical trials to Kansas’ rural communities

Nurse led follow-up care helps patients with lung cancer, increases clinic efficiency

Autoantibody test followed by CT imaging may reduce lung cancer mortality, study shows

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