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BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Arthritis flares - the unpredictable and often sudden worsening of arthritis symptoms -- can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians.

3 Apr 2018

Human genome is like a time machine, says researcher

The human genome is a bit like a time machine, says Ben Voight, an associate professor in Systems Pharmacology and Translational Therapeutics and of Genetics in Penn's Perelman School of Medicine.

3 Apr 2018

Researchers fabricate injectable bandage to promote wound healing

A penetrating injury from shrapnel is a serious obstacle in overcoming battlefield wounds that can ultimately lead to death.Given the high mortality rates due to hemorrhaging, there is an unmet need to quickly self-administer materials that prevent fatality due to excessive blood loss.

3 Apr 2018

First-of-its-kind cancer drug effective in 93% of pediatric patients

A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern's Simmons Cancer Center announced.

30 Mar 2018

AXT installs state-of-the-art crystallography system at University of Western Australia

AXT have recently completed the first Australian installation of a XtaLAB Synergy-S protein X-ray crystallography system from Rigaku Oxford Diffraction in Australia, the world leaders in crystallography.

From AXT Pty Ltd 30 Mar 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

Scientists identify early markers of infection in nonhuman primates exposed to Ebola virus

Scientists have identified potential biomarkers in nonhuman primates exposed to Ebola virus (EBOV) that appeared up to four days before the onset of fever, according to research published today in the journal Science Translational Medicine.

28 Mar 2018

C-Path and CHDI announce launch of Huntington's Disease Regulatory Science Consortium

The Critical Path Institute, together with CHDI Foundation, Inc., today announced the official launch of C-Path's Huntington's Disease Regulatory Science Consortium.

28 Mar 2018

Researchers discover important features of tumor cells that may help fight cancer

A research team led by Mónica Bettencourt Dias, from Instituto Gulbenkian de Ciência, discovered important features of cancer cells that may help clinicians fighting cancer.

28 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Non-psychoactive cannabis ingredient could reduce risk of relapse among recovering addicts

A preclinical study in rats has shown that there might be value in using a non-psychoactive and non-addictive ingredient of the Cannabis sativa plant to reduce the risk of relapse among recovering drug and alcohol addicts.

23 Mar 2018

New test for urothelial cancers offers less invasive, more accurate detection

A new test for urothelial cancers could detect mutations in DNA that have been identified for those cancers earlier than traditional tests. The earlier detection of urothelial cancer could lead to earlier treatment, and potentially better outcomes for patients.

23 Mar 2018

Restoring enzyme may help reverse effects of vascular aging, study shows

As people age, their blood-vessel density and blood flow decrease, which is why it's harder to maintain muscle mass after 40 and endurance in the later decades, even with exercise.

23 Mar 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

New findings could have revolutionary impact on quality of life of older people

Researchers from UNSW and Harvard Medical School have discovered that replacing two naturally occurring molecules in the body could reverse symptoms of aging, potentially influencing how the body responds to and performs exercise.

22 Mar 2018

New computational method helps to identify tumor cell mutations with greater accuracy

A new computational method developed by researchers at the New York Genome Center allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available approaches.

22 Mar 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

Verge joins Genomics England’s Discovery Forum industry partnership

Genomics England and Verge Genomics, a leading artificial intelligence therapeutics company, announced today that Verge will join Genomics England’s Discovery Forum industry partnership. The partnership aims to translate groundbreaking research into innovative treatments, and ultimately patient benefit, as rapidly as possible.

From Genomics England 20 Mar 2018

Therapeutics News and Research

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Human genome is like a time machine, says researcher

Researchers fabricate injectable bandage to promote wound healing

First-of-its-kind cancer drug effective in 93% of pediatric patients

AXT installs state-of-the-art crystallography system at University of Western Australia

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

New $3.2 million grant funds research to advance promising malaria vaccine

Scientists identify early markers of infection in nonhuman primates exposed to Ebola virus

C-Path and CHDI announce launch of Huntington's Disease Regulatory Science Consortium

Researchers discover important features of tumor cells that may help fight cancer

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Antibody sweeps away Alzheimer's plaques in mice

Non-psychoactive cannabis ingredient could reduce risk of relapse among recovering addicts

New test for urothelial cancers offers less invasive, more accurate detection

Restoring enzyme may help reverse effects of vascular aging, study shows

New study identifies key cellular mechanisms behind vascular aging in mice

New findings could have revolutionary impact on quality of life of older people

New computational method helps to identify tumor cell mutations with greater accuracy

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

Verge joins Genomics England’s Discovery Forum industry partnership

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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