Liver News and Research

RSS

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

Disruptions in a protein folding process occurring in the brain, known as endoplasmic reticulum (ER) stress, may cause non-alcoholic fatty liver disease, independent of other factors. A research team at the George Washington University published their results in the Journal of Clinical Investigation Insight.

25 May 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Molecule discovered in worm spit could offer solution for non-healing wounds

Every day 12 Australian diabetics have a limb amputated because of a non-healing wound. Globally, it's one every 30 seconds.

25 May 2017

Biochemists create new tool to help diagnose POLG disorders and predict outcomes

Providing answers -- or at least more information -- to the most difficult medical questions is the aim of medical scientists. And how research findings are translated and made available can be as important as the discoveries themselves.

24 May 2017

Medical methods in the life of Shakespeare’s son-in-law

During this period, there was a revival of the Classical medicine of Ancient Greece and Rome, particularly the ideas of the Greek philosopher Hippocrates and the Roman physician Galen of Pergamon.

24 May 2017

New study offers insight into how to improve chemotherapy strategies for ovarian cancer

Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate all of the cancer cells because they have spread throughout the abdomen. Surgery is therefore followed by 18 weeks of chemotherapy.

24 May 2017

FDA grants accelerated approval to cancer treatment based on common biomarker

The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker).

23 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Researchers demonstrate multicolor 3D imaging of live mouse using compact Compton camera

Researchers invented a Compton camera of 580g which visualizes gamma rays of arbitrary energies, and succeeded in achieving a high-resolution, multicolor 3D molecular image of a live mouse administered with three different radioactive tracers in just 2 hours.

23 May 2017

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report by the American Institute for Cancer Research and the World Cancer Research Fund.

23 May 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

Light-inducible antimiRs could improve wound healing in diabetes patients

MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs.

19 May 2017

New findings could lead to first broadly effective ebolavirus therapies and vaccines

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.

19 May 2017

Researchers discover how the injured brain alerts immune system

Johns Hopkins researchers say they have identified a new way that cells in the brain alert the rest of the body to recruit immune cells when the brain is injured. The work was completed in mouse models that mimic infection, stroke or trauma in humans.

18 May 2017

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Seventh Wave Laboratories, a consulting-based contract research organization that assesses the safety and efficacy of pharmaceutical products and medical devices, has announced an exclusive collaboration with Yecuris Corporation, a global leader in the development and use of humanized models in drug development research.

18 May 2017

Liver News and Research

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

Molecule discovered in worm spit could offer solution for non-healing wounds

Biochemists create new tool to help diagnose POLG disorders and predict outcomes

Medical methods in the life of Shakespeare’s son-in-law

New study offers insight into how to improve chemotherapy strategies for ovarian cancer

FDA grants accelerated approval to cancer treatment based on common biomarker

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Researchers demonstrate multicolor 3D imaging of live mouse using compact Compton camera

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Light-inducible antimiRs could improve wound healing in diabetes patients

New findings could lead to first broadly effective ebolavirus therapies and vaccines

Researchers discover how the injured brain alerts immune system

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Research paves way for safer and more effective drugs to treat type 2 diabetes

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

Targeted therapy appears to be more effective in preventing lung cancer recurrence

Researchers identify DNA repair deficiency in many types of solid tumors

Researchers identify key inflammatory cells involved in nonalcoholic fatty liver disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News