Therapeutics News and Research

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Speeding up wound healing using nanofiber dressings

Scientists have developed two new types of wound dressing that dramatically increase healing rates and improve tissue regeneration.

19 Mar 2018

Research establishes use of chimeric cells as potential therapy for Duchenne muscular dystrophy

Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy --a rare but fatal form of muscular dystrophy -- were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease.

16 Mar 2018

Alzheimer's disease also affects small blood vessels

A research conducted by the UAB demonstrates that mice suffering from this disease also have substantial malfunctions in small blood vessels, important in nourishing different organs and tissues and in regulating blood pressure, and which mainly affects females.

16 Mar 2018

Ludwig researchers extend potential for personalized immunotherapy to ovarian cancer, other tumors

A Ludwig Cancer Research study shows that ovarian cancer, which has proved resistant to currently available immunotherapies, could be susceptible to personalized immunotherapy.

15 Mar 2018

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Dr. Adam W. Smith, assistant professor in the Department of Chemistry, has won a CAREER award from the National Science Foundation. The title of the award is "Lipid Regulation of Receptor Tyrosine Kinases" and provides $650,000 of funding for research.

15 Mar 2018

Researchers uncover new way to treat aggressive breast tumors

Researchers at Lund University and Karolinska Institutet have uncovered a way to treat aggressive breast tumors through manipulation of the connective tissue cells of the tumor.

13 Mar 2018

$Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients$

Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients

Long-term proton pump inhibitor (PPI) use does not increase the risk of hip fracture among persons with Alzheimer's disease, according to a new study from the University of Eastern Finland.

13 Mar 2018

Researchers create cardiomyocyte molds to mend broken hearts

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

13 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

Study sheds new light on viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine showed how a common virus hijacks a host cell's protein to help assemble new viruses before they are released.

13 Mar 2018

Flatfoot reconstruction can be viable option for elderly patients, study finds

When someone develops adult-acquired flatfoot deformity (AAFD), they are offered either a reconstruction or foot fusion depending on the severity of the flatfoot and their age. Typically reconstructions are performed in younger patients, while older patients undergo fusions, even though it can limit mobility.

13 Mar 2018

Novel screening tool aids search for curative kidney treatment

Researchers have developed a screening tool for identifying compounds that restore functionality of the protein that is dysfunctional in Alport syndrome.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Study finds reduced risk of dislocations with dual mobility hip replacement

More than 330,000 total hip replacements are performed in the United States each year. Overall, it is a highly successful procedure. However, as with all surgeries, a risk for complications exists.

7 Mar 2018

New analysis finds link between inflammatory bowel disease and history of weight loss surgery

A new Alimentary Pharmacology & Therapeutics analysis has found a link between the development of inflammatory bowel disease and a past history of weight loss surgery.

7 Mar 2018

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

An international research team led by the Institute of Bioengineering and Nanotechnology of the Agency for Science, Technology and Research and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects.

7 Mar 2018

Innovative antibody delivery method could offer effective way to combat Ebola infection

More than 11,000 people died during the Ebola outbreak in West Africa from 2013-16, demonstrating both the deadly nature of the virus and the limitations of the medication used to fight it.

6 Mar 2018

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

If you're an immune cell gearing up to fight cancer, you'd better eat your breakfast. The tumor microenvironment is a harsh place, and tumor cells are ready to wear you out.

6 Mar 2018

Therapeutics News and Research

Speeding up wound healing using nanofiber dressings

Research establishes use of chimeric cells as potential therapy for Duchenne muscular dystrophy

Alzheimer's disease also affects small blood vessels

Ludwig researchers extend potential for personalized immunotherapy to ovarian cancer, other tumors

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Researchers uncover new way to treat aggressive breast tumors

Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients

Researchers create cardiomyocyte molds to mend broken hearts

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Study sheds new light on viral replication

Flatfoot reconstruction can be viable option for elderly patients, study finds

Novel screening tool aids search for curative kidney treatment

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Researchers identify new mechanism to disrupt HIV latency

Study finds reduced risk of dislocations with dual mobility hip replacement

New analysis finds link between inflammatory bowel disease and history of weight loss surgery

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

Innovative antibody delivery method could offer effective way to combat Ebola infection

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

Next-generation therapeutics eBook eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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