Immune Response News and Research

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Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Researchers identify new way to increase immune response against cancer and infections

An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve-Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T-cells of the immune system to react against foreign antigens and cancer.

19 Jul 2017

Unique 'Golden Hour' study details ultra-early immune response to trauma

Scientists from the University of Birmingham are carrying out pioneering research as part of a major £10 million study aimed at improving outcomes for patients who have suffered a traumatic injury.

19 Jul 2017

CNIC research holds potential to improve current cancer immunotherapy strategies

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response.

17 Jul 2017

Lymph node removal may not be needed for all melanoma patients, study finds

Many patients with melanoma need a sentinel-lymph-node biopsy to determine if cancer cells have spread there, but a positive finding doesn't mean all the lymph nodes in the area must be removed, according to new international study.

17 Jul 2017

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

Researchers from the University of Southampton have identified why some people may become resistant to monoclonal antibodies, a common type of immunotherapy used in lymphoma treatment.

17 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

Diabetes-induced changes in oral microbiome promote periodontal bone loss

A new study led by University of Pennsylvania researchers has found that the oral microbiome is affected by diabetes, causing a shift to increase its pathogenicity.

12 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

11 Jul 2017

Scientists develop potential new therapy for targeting skin cancer metastases in the brain

Investigators from Brigham and Women's Hospital (BWH) and the Harvard Stem Cell Institute have a potential solution for how to kill tumor cells that have metastasized to the brain.

10 Jul 2017

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

A team led by Gang Han, PhD, has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging contrast that can be easily cleared by the body.

10 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Novel vaccine approach appears to protect fetus from CMV infection, animal study shows

Long before the Zika virus became a global fear, cytomegalovirus, or CMV, was commonly infecting developing fetuses and causing many of the same brain and developmental impairments.

6 Jul 2017

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

A novel, synthetic, DNA-based strategy to provide protection against a broad array of influenza viruses has been developed in preclinical models by scientists at The Wistar Institute, MedImmune (the global biologics research and development arm of AstraZeneca) and Inovio Pharmaceuticals, Inc.

6 Jul 2017

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

A personal cancer treatment vaccine that targets distinctive "neoantigens" on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

5 Jul 2017

Immune Response News and Research

Two cell types partner to protect pancreatic tumors from immune attack

Researchers identify new way to increase immune response against cancer and infections

Unique 'Golden Hour' study details ultra-early immune response to trauma

CNIC research holds potential to improve current cancer immunotherapy strategies

Lymph node removal may not be needed for all melanoma patients, study finds

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

Scientists positively influence immune response in viral and bacterial co-infection

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Diabetes-induced changes in oral microbiome promote periodontal bone loss

Targeting acid metabolite reduces size and spread of breast cancer

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Scientists develop potential new therapy for targeting skin cancer metastases in the brain

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

JAX researchers explore how dendritic cells promote adaptive immunity to virus

Novel vaccine approach appears to protect fetus from CMV infection, animal study shows

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

Discovery could impact understanding, treatment of autoimmune and inflammatory diseases

Combination treatment could be more effective against common infection

New portable device can quickly find markers of sepsis from single drop of blood

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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