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Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

Obese women may get less dangerous form of preeclampsia, study suggests

Despite having higher rates of preeclampsia, a dangerous high-blood pressure disorder of late pregnancy, obese women may be less than half as likely to suffer strokes, seizures, and other serious complications of the disorder. The

5 May 2017

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

In a new study, Roswell Park Cancer Institute researchers have demonstrated that an approach shown to improve outcomes for patients receiving colorectal surgery is just as effective in patients requiring many other abdominal and pelvic operations.

5 May 2017

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching.

5 May 2017

Long periods of physiological stress can change composition of intestinal microbiota in soldiers

A new study finds that long periods of physiological stress can change the composition of microorganisms residing in the intestines, which could increase health risks in endurance athletes and military personnel.

4 May 2017

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Men and women differ in obvious and less obvious ways -- for example, in the prevalence of certain diseases or reactions to drugs. How are these connected to one's sex? Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed -- copied out to make proteins -- differently in the two sexes.

4 May 2017

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Researchers at Baylor College of Medicine have discovered that changing the circadian clock in mouse liver can alter how the body responds to diet and also change the microbes living in the digestive track.

4 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

Scientists grow and purify earliest lung progenitors from human stem cells

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. They gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide.

3 May 2017

New review explains how calorie restriction can extend life

A new review proposes a theory to explain how calorie restriction can extend life across a variety of species.

3 May 2017

Moderate cardiorespiratory fitness can protect from fatty liver

According to a new Finnish study, cardiorespiratory fitness is inversely related to risk of fatty liver. The research was conducted at the University of Turku, Finland, and shows that, despite the person's weight, achieving moderate cardiorespiratory fitness can protect from fatty liver.

3 May 2017

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Researchers have discovered that a new anti-rejection drug that is gentler on the kidneys after liver transplant also reduces weight gain, which is common after surgery and can lead to serious complications for transplant patients.

3 May 2017

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

New research on nanodiamond-enhanced MRI

Research by a collaboration of scientists in Australia and the United States demonstrates that using nanodiamonds somewhat like ‘tiny machines’ inside living patients has taken a quantum leap closer to reality.

3 May 2017

Discovery of protein that causes liver disease brings hope for new treatments

In a world-first discovery, scientists at Sydney’s Westmead Institute for Medical Research have identified a protein that causes liver fibrosis (scarring), paving the way for new treatments for liver disease to be developed.

3 May 2017

PCSK9 Inhibitors: Highlights barriers to new, breakthrough cholesterol-lowering drugs

Today the Partnership to Advance Cardiovascular Health released a new web video, “PCSK9 Inhibitors: Access Barriers Affect Real People” The video, featuring patient testimonials, explores access issues to new, breakthrough cholesterol-lowering drugs known as PCSK9 inhibitors.

3 May 2017

Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Nonalcoholic fatty liver disease (NAFLD) - a condition that can lead to liver cirrhosis and cancer - isn't typically detected until it's well advanced. Even then, diagnosis requires an invasive liver biopsy.

2 May 2017

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Scientists from the National University of Singapore have developed a novel nanodiamond-based contrast agent - a chemical "dye" used to enhance the visibility of internal body structures in magnetic resonance imaging - that improves visualization of liver cancer tumors

2 May 2017

Liver News and Research

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Obese women may get less dangerous form of preeclampsia, study suggests

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Long periods of physiological stress can change composition of intestinal microbiota in soldiers

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Phagocytosis educates the immune system

Scientists grow and purify earliest lung progenitors from human stem cells

New review explains how calorie restriction can extend life

Moderate cardiorespiratory fitness can protect from fatty liver

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

Researchers uncover new mechanism that explains cause of portal hypertension

New research on nanodiamond-enhanced MRI

Discovery of protein that causes liver disease brings hope for new treatments

PCSK9 Inhibitors: Highlights barriers to new, breakthrough cholesterol-lowering drugs

Infantile spasms and multiple sclerosis relapse data presented at AAN

Study sets stage for potential stool-based test to detect advanced liver fibrosis

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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