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Pathogenesis of Campylobacter jejuni-related disease

Campylobacters are small Gram-negative spiral rods. Campylobacter jejuni (C. jejuni), a foodborne organism contracted from untreated water, milk and meat, especially chicken, is one of the most important causes of bacterial diarrhea worldwide. However, its mode of pathogenesis is not clear.

1 Jan 2009

Scientists genetically grab PTEN by the tail to curtail cancer

When researchers look inside human cancer cells for the whereabouts of an important tumor-suppressor, they often catch the protein playing hooky, lolling around in cellular broth instead of muscling its way out to the cells' membranes and foiling cancer growth.

1 Jan 2009

Researchers look at anti-tumor mechanisms of Scutellaria barbata

Medicinal plants have been used as traditional remedies for hundreds of years.

1 Jan 2009

Researchers look at processes asbestos fibers use to trigger cancer in human cells

Ohio State University scientists believe they are the first in the world to study the molecular underpinnings of cancer by probing individual bonds between an asbestos fiber and human cells.

18 Dec 2008

New understanding of ion channels in the body

A discovery by Canada-U.S. biophysicists will improve the understanding of ion channels, akin to little 'nano-machines' or 'nano-valves' in our body, which when they malfunction can cause genetic illnesses that attack muscles, the central nervous system and the heart.

18 Dec 2008

Primary cilium's GPS-like cell structure crucial to wound repair

The primary cilium, the solitary, antenna-like structure that studs the outer surfaces of virtually all human cells, orient cells to move in the right direction and at the speed needed to heal wounds, much like a Global Positioning System helps ships navigate to their destinations.

17 Dec 2008

Key survival circuit discovered in Salmonella bacteria

Hundreds of trillions of bacteria make their home in the vertebrate gut. Though many of these microbes perform helpful duties for their host, others - the pathogens - are unwelcome visitors, causing disease.

17 Dec 2008

Scientists fool bacteria into programming own death

Like firemen fighting fire with fire, researchers at the University of Illinois and the University of Massachusetts at Amherst have found a way to fool a bacteria's evolutionary machinery into programming its own death.

16 Dec 2008

Natural product from red seaweed brings new antiviral spray

Marinomed Biotechnologie GmbH has been awarded the top prize in the Mercur 2008 innovation awards. This award to Marinomed honours the discovery of antiviral properties in a natural product and the rapid development of the discovery into a nasal spray for treating the common cold.

16 Dec 2008

New technique to view labeled tumor cells in 'real' time

A breakthrough technique that allows scientists to view individually-labeled tumor cells as they move about in real time in a live mouse may enable scientists to develop microenvironment-specific drugs against cancer, researchers report at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

15 Dec 2008

GUMC researchers find gene inactivated in two aggressive cancers

Researchers at Georgetown University Medical Center have found a gene they say is inactivated in two aggressive cancers - malignant melanoma, a form of skin cancer, and glioblastoma multiforme, a lethal brain tumor.

15 Dec 2008

Single adult stem cell can self-renew in a mammal

The first demonstration that a single adult stem cell can self-renew in a mammal was reported at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

14 Dec 2008

Promising clinical trial for Progeria "premature aging" disease

One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Sunday, Dec. 14, at the American Society for Cell Biology (ASCB)'s annual meeting in San Francisco.

14 Dec 2008

New biosensor could help the search for new drugs

Chalmers researcher Andreas Dahlin has developed a biosensor with an artificial membrane, which means that membrane-bound proteins can retain their natural structure and function.

10 Dec 2008

Mathematical model shows how organelles function within cells

Cells are filled with membrane-bound organelles like the nucleus, mitochondria and endoplasmic reticula.

8 Dec 2008

Biologists spy close-up view of poliovirus linked to host cell receptor

Researchers from Purdue and Stony Brook universities have determined the precise atomic-scale structure of the poliovirus attached to key receptor molecules in human host cells and also have taken a vital snapshot of processes leading to infection.

8 Dec 2008

New insights into cell division

Biologists have discovered a mechanism that is critical to cytokinesis -- nature's completion of mitosis, where a cell divides into two identical daughter cells.

5 Dec 2008

Stem cells derived from bone marrow may offer novel therapeutic option for epidermolysis bullosa

Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology.

5 Dec 2008

Doing the math for membranes

Determining the mechanisms that shape biological membranes has long been a tricky business. Like a factory assembly line, eukaryotic cells are organized into membrane-bound, functional compartments called organelles.

4 Dec 2008

Natural killer T cells play important role in Lyme disease

A research team led by the La Jolla Institute for Allergy & Immunology and Albany Medical College has illuminated the important role of natural killer (NK) T cells in Lyme disease, demonstrating that the once little understood white blood cells are central to clearing the bacterial infection and reducing the intensity and duration of arthritis associated with Lyme disease.

3 Dec 2008