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New slow-release system mimics nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties.

14 Sep 2021

ICUs are filled with covid — and regret

It's a struggle for Joe Gammon to talk. Lying in his bed in the intensive care unit at Ascension Saint Thomas Hospital in Nashville, Tennessee, this month, he described himself as "naive."

14 Sep 2021

Immune-mediated inflammatory disease may increase risk of severe COVID-19 outcomes

Researchers in the UK have conducted a large population-based study showing that people with immune-mediated inflammatory diseases (IMIDs) appear to be at an increased risk of serious outcomes from coronavirus disease 2019 (COVID-19).

14 Sep 2021

Rutgers study examines link between COVID-19 and memory loss, dementia

A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, "brain fog," and dementia.

13 Sep 2021

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

Now, a new study published on the bioRxiv* preprint server investigates this relationship further and suggests that current smoking is not associated with a higher incidence of SARS-CoV-2 infection.

13 Sep 2021

Enhanced recovery after surgery program helps reduce opioid prescriptions after lung surgery

Lung surgery patients who utilize a comprehensive, evidence-based enhanced recovery after surgery (ERAS) program require fewer opioid prescriptions when discharged and this effect was sustained over the 4-year study period, according to research presented today at the 18th Annual Perioperative and Critical Care Conference from The Society of Thoracic Surgeons.

10 Sep 2021

Chewing gum after cardiac surgery may accelerate the return of gut function

Chewing gum after heart surgery may kickstart the digestive tract, helping patients feel better and potentially be discharged sooner than those who don't use this generally safe and simple intervention, according to research presented today at the 18th Annual Perioperative and Critical Care Conference from The Society of Thoracic Surgeons.

10 Sep 2021

Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

Combating the fourth wave of COVID-19 in Ontario

Researchers from Canada recently attempted to project the number of COVID-19 cases and the demand for acute hospital resources for Fall 2021 in a mid-sized southwestern Ontario community. They sought to evaluate if current vaccine coverage and contact reduction levels are sufficient to mitigate a possible 4th wave driven by the Delta variant, or if stricter public health measures need to be reinstituted.

8 Sep 2021

New suggestions emphasize the importance of contingency level care during COVID-19 pandemic

The journal CHEST recently published an important update to the 2014 consensus statement by the Task Force for Mass Critical Care (TFMCC) on providing mass critical care utilizing research gained through experiencing the 2020 COVID-19 pandemic.

8 Sep 2021

Study reveals better outcomes for patients treated on a mobile stroke unit

Ischemic stroke patients treated on a mobile stroke unit received anti-clot medication faster and ended up with less disability at 90 days, according to a study published today in the New England Journal of Medicine led by researchers at The University of Texas Health Science Center at Houston and Memorial Hermann-Texas Medical Center.

8 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

Hotter weather associated with worsening of COPD symptoms

Warmer weather is linked to a worsening of chronic obstructive pulmonary disease (COPD) symptoms, according to research to be presented on Sunday at the 'virtual' European Respiratory Society International Congress.

3 Sep 2021

Losing weight and treating excess fat levels may help prevent lung disease in 9/11 firefighters

Losing weight and treating excess levels of fat in the blood may help prevent lung disease in firefighters who were exposed to dangerous levels of fine particles from fire, smoke, and toxic chemicals on September 11, 2001, a new study shows.

2 Sep 2021

Growing use of mechanical circulatory support causes moral distress among clinicians

The growing use of mechanical circulatory support (MCS) may contribute to high levels of moral distress for clinicians who regularly care for critically ill patients receiving the aggressive but life-sustaining therapy, according to a study in American Journal of Critical Care.

1 Sep 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Rescue breathing cardiopulmonary resuscitation (CPR) had superior neurological outcomes compared with compression-only CPR or no CPR at all in infants, children and adolescents, according to a new analysis published today in the Journal of the American College of Cardiology.

30 Aug 2021

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

In a study in mice, Johns Hopkins Medicine researchers have found that the smooth muscle cells lining the walls of blood vessels can lose their elasticity and lead to vascular stiffening, a condition that can precede heart disease and stroke.

26 Aug 2021

Researchers identify numerous genetic regions that may affect individuals' food intake

A team of researchers at Massachusetts General Hospital, Boston University School of Public Health, and other institutions have identified more than two dozen genetic regions that may affect individuals' food intake.

25 Aug 2021

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

On a July afternoon, Federico Gomez Gil, 56, is dressed in a short-sleeved, collared shirt, sweatpants and a baseball cap. He sits in a chair in a hospital room, surrounded by his wife and two daughters. Given the past five months, this is the moment of a lifetime — a new lifetime.

24 Aug 2021

Critical Care News and Research

New slow-release system mimics nature to provide long-lasting local anesthesia

ICUs are filled with covid — and regret

Immune-mediated inflammatory disease may increase risk of severe COVID-19 outcomes

Rutgers study examines link between COVID-19 and memory loss, dementia

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

Enhanced recovery after surgery program helps reduce opioid prescriptions after lung surgery

Chewing gum after cardiac surgery may accelerate the return of gut function

Enzyme appears to be a major driver of dangerous pregnancy complication

Combating the fourth wave of COVID-19 in Ontario

New suggestions emphasize the importance of contingency level care during COVID-19 pandemic

Study reveals better outcomes for patients treated on a mobile stroke unit

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Hotter weather associated with worsening of COPD symptoms

Losing weight and treating excess fat levels may help prevent lung disease in 9/11 firefighters

Growing use of mechanical circulatory support causes moral distress among clinicians

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

Researchers identify numerous genetic regions that may affect individuals' food intake

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

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