Developmental Biology News and Research

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Neuronal transport factor detects its target transcripts in more complex manner than previously thought

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought.

16 Apr 2019

New imaging technology will improve understanding of embryonic development

Soon after conception, an embryo's circulatory system connects to that of its mother. Complications that occur at this critical time can result in miscarriage or birth defects with long-term chronic conditions.

9 Apr 2019

Researchers track effects of epigenetic marks carried by sperm chromosomes

As an organism grows and responds to its environment, genes in its cells are constantly turning on and off, with different patterns of gene expression in different cells. But can changes in gene expression be passed on from parents to their children and subsequent generations?

20 Mar 2019

Creating increasingly complex brain organoids

Scientists improved the initial steps of a standard protocol and produced organoids displaying regionalized brain structures, including retinal pigmented cells. The announcement was published today in BMC Developmental Biology by the D'Or Institute for Research and Education's team.

8 Mar 2019

Researchers elucidate how embryonic cells and tissues respond to force

Accumulated evidence suggests that physical force plays an important role in various developmental processes of fertilized animal eggs.

8 Mar 2019

Study sheds new light on early development of embryos

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.

5 Mar 2019

Researchers identify origin of immune cell that helps form healthy heart valves

UCLA researchers have identified for the first time the origin of an immune cell that plays a critical role in the formation of healthy heart valves. The findings could pave the way for new treatments for heart valve disorders, which can be caused by congenital defects, aging or disease.

22 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Scientists develop new gene therapy that prevents axon destruction in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch.

18 Jan 2019

New findings bring about better understanding of many cancers' metabolic needs

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism.

10 Jan 2019

Washington University scientists find an unknown route for cellular fuel delivery

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it.

8 Jan 2019

Rutgers scientists take an important step in making diseased hearts heal themselves

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves - a new model that would reduce the need for bypass surgery, heart transplants or artificial pumping devices.

17 Dec 2018

ZEISS teams up with arivis AG to offer complete 3D imaging solutions

ZEISS has teamed up with arivis AG to offer complete solutions from initial image acquisition to final results.

From ZEISS Microscopy GmbH 15 Nov 2018

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.

14 Nov 2018

UCLA researchers investigate how a protein factor contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.

1 Nov 2018

Toxic protein assemblies found to play beneficial role in muscle generation

Toxic protein assemblies, or "amyloids," long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers have found.

1 Nov 2018

Study offers hope of early detection, treatment of liver cancer

Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments.

31 Oct 2018

3 Harvard scientists receive Allen awards for work in neuroimmunology, developmental biology, cancer

Three Harvard Medical School scientists have received the prestigious Allen Distinguished Investigator awards for their work in the fields of neuroimmunology, developmental biology and cancer.