Mitochondria News and Research

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Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Scientists at the Icahn School of Medicine at Mount Sinai in New York, the National Center for Advancing Translational Sciences (NCATS), and elsewhere have reversed the effects of several life-threatening inherited neurodegenerative diseases called lysosomal storage disorders (LSDs) in patient cells and mice.

9 Sep 2022

Intelligent fluorescent microscope for imaging biological events in detail

Imagine you're a PhD student with a fluorescent microscope and a sample of live bacteria. What's the best way use these resources to obtain detailed observations of bacterial division from the sample?

9 Sep 2022

Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Energy supply is a vital component of economic life. And the complex interplay between society and economy is jeopardized whenever core services or key industrial sectors are at risk of failing because of energy supply problems.

7 Sep 2022

Research reveals a starring role for mitochondrial dynamics within adult muscle stem cells

Mitochondria are remarkable shape-shifting organelles that have long been understood as the powerhouses inside our cells.

2 Sep 2022

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death.

1 Sep 2022

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson's disease, ultimately causing nerve cell death.

30 Aug 2022

New treatment may be effective in addressing the long-term effects of preeclampsia

Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother.

30 Aug 2022

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial mutations to observe these tiny organelles.

30 Aug 2022

Study reveals a 'stealing' mechanism that contributes to antibody diversity

A few years ago, Professor Kathrin de la Rosa and her colleagues in the lab of the Swiss immunologist Antonio Lanzavecchia made an unusual discovery.

29 Aug 2022

Single administration of alcohol can permanently alter the morphology of neurons

A research team from the University of Cologne and the Universities of Mannheim and Heidelberg has found that even the single administration of alcohol permanently alters the morphology of neurons.

26 Aug 2022

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers compare the length spectra of sperm mitochondrial DNA deletions in two seasons with varied air pollution levels.

14 Aug 2022

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

NIH researchers develop three-dimensional structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.

5 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

The aging human brain

Researchers describe alterations at the molecular and cellular levels that underly brain aging in otherwise healthy elderly adults.

3 Aug 2022

Light-activated proteins can help normalize dysfunction within cells, study shows

New research from the University of Cincinnati shows early indications that light can be used as a treatment for certain diseases, including cancer.

2 Aug 2022

New, non-invasive imaging method may help detect an early indicator of glaucoma

A new, non-invasive ocular imaging method may be able to detect an early indicator of glaucoma in time to prevent disease progression and vision loss, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

2 Aug 2022

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

A team led by biologists at The University of Texas at Arlington has published a study supporting the theory that species that reproduce asexually have more harmful genetic mutations than those utilizing sexual reproduction.

1 Aug 2022

Nanoparticles' toxic effects on macrophages

Researchers summarize the toxic effects of nanoparticles on macrophages in vitro.

31 Jul 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

Mitochondria News and Research

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Intelligent fluorescent microscope for imaging biological events in detail

Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Research reveals a starring role for mitochondrial dynamics within adult muscle stem cells

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

New treatment may be effective in addressing the long-term effects of preeclampsia

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Study reveals a 'stealing' mechanism that contributes to antibody diversity

Single administration of alcohol can permanently alter the morphology of neurons

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

NIH researchers develop three-dimensional structure of twinkle protein

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

The aging human brain

Light-activated proteins can help normalize dysfunction within cells, study shows

New, non-invasive imaging method may help detect an early indicator of glaucoma

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

Nanoparticles' toxic effects on macrophages

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

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