Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Rigel Pharmaceuticals reports net loss of $22.3 million for first quarter 2014

Rigel Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2014.

7 May 2014

Global risk assessment urged for hypertensive patients

Global risk assessment has a large impact on the risk stratification and therefore management of patients with hypertension, a study shows.

6 May 2014

Phosphate linked to cause high blood pressure and heart disease

Researchers find link between phosphate rich foods and an enzyme linked to cardiovascular disease. The findings also link phosphates to renal disease.

6 May 2014

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

In the U.S. alone, more than 1.5 million people have lupus, a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. The symptoms can range from debilitating pain and fatigue to organ failure.

6 May 2014

Long-term use of drug combination reduces risk of recurrent urinary tract infection in children

Long-term use of a drug combination reduces the risk of recurrent urinary tract infection by up to 80 percent in children with the urinary condition vesicoureteral reflux compared to placebo, according to research funded by the National Institutes of Health.

5 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Young onset age heightens Type 2 diabetes complication risks

Patients who develop Type 2 diabetes before the age of 40 years have higher complication risks at any given age than those who develop it later in life, research shows.

28 Apr 2014

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

Concert Pharmaceuticals, Inc. today announced 48-week results of its Phase 2 clinical trial of CTP-499 in patients with diabetic kidney disease. CTP-499, when used in addition to the standard of care, is being developed to delay the progression of these patients to end-stage renal failure, which requires dialysis or kidney transplantation.

26 Apr 2014

DaVita Kidney Care expands care of kidney patients in Malaysia

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, today announced it acquired three hemodialysis centers from Malaysian dialysis provider Sinar Indentiti Sbn Bhd, further expanding its care of kidney patients in the country.

23 Apr 2014

Prenatal risk factors linked with development of chronic kidney disease in children

Certain prenatal risk factors are associated with the development of chronic kidney disease in children, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). Future studies should investigate whether modifying these factors could help protect children's kidney health.

18 Apr 2014

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, today announced it has completed enrollment in its ongoing 200-patient Phase 2b study of AKB-6548 for the treatment of anemia associated with chronic kidney disease (CKD) in patients who are not dependent on dialysis.

16 Apr 2014

NEPHRON+ project improves lives of kidney failure patients by developing wearable artificial kidney device

End stage kidney disease is a global public health problem with an estimated 2.4 million patients on dialysis. The number of new cases is rising (7-8% annually) due to population ageing and increased diabetes prevalence.

15 Apr 2014

Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

The mechanism which underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by Wellcome Trust-funded medical scientists, who have also suggested a possible treatment to reverse immune suppression in these patients.

15 Apr 2014

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.

15 Apr 2014

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

Proteomics now seeks a commercialisation partner to enter the RUO, LDT or IVD markets. Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein biomarkers.

11 Apr 2014

RWJUH offers new alternative to open up blocked arteries

Treatment options for high-risk heart patients with severely calcified coronary artery disease (CAD) have been limited for more than 20 years. Now, Robert Wood Johnson University Hospital offers a new alternative to open up blocked arteries.

11 Apr 2014

Clinical Research Forum announces winners of third annual Top 10 Clinical Research Achievement Awards

The Clinical Research Forum has announced the winners of its third annual Top 10 Clinical Research Achievement Awards. The winning projects represent the outstanding examples of research projects that benefit the health and well-being of the general public.

11 Apr 2014

Loyola University Medical Center designated as Comprehensive Hypertension Center

Loyola University Medical Center has been approved as a Comprehensive Hypertension Center by the American Society of Hypertension. This designation recognizes centers that have demonstrated the highest level of expertise in treating patients with complex hypertension and co-existing medical conditions such as diabetes and chronic kidney disease.

11 Apr 2014

President of ASN urges Congress to spur scientific innovation in kidney research through federal prize competition

Today the President of the American Society of Nephrology (ASN) urged Congress to spur scientific innovation in kidney research through a federal prize competition.

10 Apr 2014

Mayo Clinic research shows RA patients more likely to develop chronic kidney disease

Rheumatoid arthritis patients are likelier than the average person to develop chronic kidney disease, and more severe inflammation in the first year of rheumatoid arthritis, corticosteroid use, high blood pressure and obesity are among the risk factors, new Mayo Clinic research shows.

10 Apr 2014

Nephropathy News and Research

Further Reading

Rigel Pharmaceuticals reports net loss of $22.3 million for first quarter 2014

Global risk assessment urged for hypertensive patients

Phosphate linked to cause high blood pressure and heart disease

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

Long-term use of drug combination reduces risk of recurrent urinary tract infection in children

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Young onset age heightens Type 2 diabetes complication risks

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

DaVita Kidney Care expands care of kidney patients in Malaysia

Prenatal risk factors linked with development of chronic kidney disease in children

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

NEPHRON+ project improves lives of kidney failure patients by developing wearable artificial kidney device

Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

RWJUH offers new alternative to open up blocked arteries

Clinical Research Forum announces winners of third annual Top 10 Clinical Research Achievement Awards

Loyola University Medical Center designated as Comprehensive Hypertension Center

President of ASN urges Congress to spur scientific innovation in kidney research through federal prize competition

Mayo Clinic research shows RA patients more likely to develop chronic kidney disease

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