Genome News and Research

RSS

New game theory approach helps identify bacterial antibiotic resistance

Washington State University researchers have developed a novel way to identify previously unrecognized antibiotic-resistance genes in bacteria.

9 Oct 2019

Vaccine for deadly RSV could be on the way, scientists say

A vaccine for the common and sometimes deadly RSV (respiratory syncytial virus) has been elusive, but scientists say a new discovery puts them much closer to success.

9 Oct 2019

Scientists discover new patterns in the evolution of the influenza virus

Researchers from Skoltech have found that the devious influenza virus is capable of new patterns of evolution and mutation in order to escape treatment with the currently available drugs and prevention with the currently available vaccines. This discovery however could help researchers predict the potential mutations in the genome of the virus and ultimately help them develop and design more effective vaccines against influenza.

9 Oct 2019

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

In 2015, EPFL researchers led by Melanie Blokesch published a seminal paper in Science showing that the bacterium responsible for cholera, Vibrio cholerae, uses a spring-loaded spear to literally stab neighboring bacteria and steal their DNA.

8 Oct 2019

New patterns discovered in the evolution of influenza virus

Skoltech scientists discovered new patterns in the evolution of the influenza virus. This may help predict mutations in the viral genome and ultimately help design better vaccines.

8 Oct 2019

Scientists make genetic data available for bacteria linked to Crohn's disease

Scientists have made genetic data publicly available for bacteria that might be lurking inside the gut walls of patients chronically affected with severe Crohn's disease.

8 Oct 2019

Histone modifications play important role in 'zygotic genome activation'

Scientists at Tokyo Institute of Technology observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to "histone H3", one of the proteins around which DNA is bound, play an important role in "zygotic genome activation" or transition of control of zebrafish embryonic development from maternal material to the zygote .

8 Oct 2019

Study presents a new view on how mitochondrial dysfunction may contribute to aging

Disturbances in the function of mitochondrial DNA can accelerate the aging process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism.

8 Oct 2019

New study advances understanding about what shapes human gut microbiome

A new Northwestern University study finds that despite human's close genetic relationship to apes, the human gut microbiome is more similar to that of Old World monkeys like baboons than to that of apes like chimpanzees.

8 Oct 2019

Cholera-causing bacteria steal large stretches of intact DNA to become more efficient

A new paper shows that the cholera germ is an inveterate and rapacious gene stealer, robbing other competing bacteria of up to 150 genes (over 150,000 base pairs) in a single attack. To put this in perspective, the cholera pathogen carries only about 4,000 genes altogether.

8 Oct 2019

New insight into meningioma - possibility of targeted therapy

A new study published in the journal Oncotarget shows that certain mutations in the brain tumor called meningioma may help identify patients who have a better chance of recovery. This could help physicians make better clinical decisions based on more accurate diagnoses. It has also unveiled some of the genes that go wrong in meningiomas, as well as showing how targeted therapy could one day help fight this tumor.

7 Oct 2019

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health's Somatic Cell Genome Editing Program.

7 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Research provides new insights into tumorigenesis of meningioma

The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy.

5 Oct 2019

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

The cover for issue 55 of Oncotarget features Figure 3, "Romidepsin exhibits anti-tumor effect in xenograft model of DDLPS," by Seligson, et al.

4 Oct 2019

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

The cover for issue 54 of Oncotarget features Figure 2, "Comparative proteomic profiling of the peptides/proteins identified from 293T, IL16lamp2b and mExo-Tat samples," by Lu, et al.

4 Oct 2019

Stanford study finds genetic similarities among species that use sound waves to navigate

Insect-eating bats navigate effortlessly in the dark and dolphins and killer whales gobble up prey in murky waters thanks in part to specific changes in a set of 18 genes involved in the development of the cochlear ganglion -- a group of nerves that transmit sound from the ear to the brain, according to a study by researchers at Stanford University.

4 Oct 2019

Genome News and Research

New game theory approach helps identify bacterial antibiotic resistance

Vaccine for deadly RSV could be on the way, scientists say

Scientists discover new patterns in the evolution of the influenza virus

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

New patterns discovered in the evolution of influenza virus

Scientists make genetic data available for bacteria linked to Crohn's disease

Histone modifications play important role in 'zygotic genome activation'

Study presents a new view on how mitochondrial dysfunction may contribute to aging

New study advances understanding about what shapes human gut microbiome

Cholera-causing bacteria steal large stretches of intact DNA to become more efficient

New insight into meningioma - possibility of targeted therapy

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

New genome-wide association study shines light on genetic risk factors for gout

Research provides new insights into tumorigenesis of meningioma

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

Stanford study finds genetic similarities among species that use sound waves to navigate

GW researchers show connection between bacteria in the microbiome and colon cancer

NIH grants boost rare diseases research efforts

The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News