Genomic News and Research

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Cypher Genomics, Illumina partner to facilitate development of genomic-based biomarkers

Cypher Genomics, Inc., the genome informatics company, announced today a co-promotion agreement with Illumina to facilitate the development of genomic-based biomarkers from whole genome sequence data for precision medicine and clinical trials.

From Illumina, Inc. 24 Jul 2014

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer.

23 Jul 2014

Research findings could lead to new approaches for treating schizophrenia

As part of a multinational, collaborative effort, researchers from the Icahn School of Medicine at Mount Sinai have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in the largest genomic study published on any psychiatric disorder to date, conducted with 80,000 people.

23 Jul 2014

Saudi Arabian researchers detect genetic fragments of MERS-CoV in the air of camel barn

Saudi Arabian researchers have detected genetic fragments of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in the air of a barn holding a camel infected with the virus. The work, published this week in mBio-, the online open-access journal of the American Society for Microbiology, indicates that further studies are needed to see if the disease can be transmitted through the air.

22 Jul 2014

Findings point to biological mechanisms and pathways that may underlie schizophrenia

As part of a multinational, collaborative effort, researchers from the University of North Carolina School of Medicine and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in what is the largest genomic study published on any psychiatric disorder to date.

22 Jul 2014

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

The New York State Department of Health (DOH) has granted Roswell Park Cancer Institute (RPCI) approval to begin genomic testing of cancer patients using its OmniSeq TargetTM advanced molecular diagnostic laboratory test.

21 Jul 2014

Genomics testing in action: an interview with Kevin Haar, CEO, Appistry

The more connections are made between genes, disease and drugs, and the more that we continue to understand about those connections, the more critical genetic testing will become in modern medicine.

21 Jul 2014

Study: Genetics plays major role in development of autism

Using new statistical tools, Carnegie Mellon University's Kathryn Roeder has led an international team of researchers to discover that most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

21 Jul 2014

Scientists reveal secrets of cell membrane proteins

Rice University scientists have succeeded in analyzing transmembrane protein folding in the same way they study the proteins' free-floating, globular cousins.

17 Jul 2014

TAZ represents a novel therapeutic target in NSCLC

Patients with non-small-cell lung cancer who express high levels of transcriptional coactivator with PDZ-binding motif may be a clinically distinct subgroup with an unfavourable prognosis, researchers report.

16 Jul 2014

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemoprevention is to arrest or reverse the progression of premalignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells.

16 Jul 2014

Research shows promise to speed up drug discovery for deadly diseases

Antibiotic resistance is depleting our arsenal against deadly diseases and infections, such as tuberculosis and Staph infections, but recent research shows promise to speed up the drug discovery process.

16 Jul 2014

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Mount Sinai Heart at Icahn School of Medicine at Mount Sinai has been awarded a $3.8 million grant by the American Heart Association to promote cardiovascular health among high-risk New York City children, and their parents, living in Harlem and the Bronx. With assistance from the NYC Administration for Children's Services, the research team's mission is to reduce each child's future risk of obesity, heart attack, stroke, and type 2 diabetes.

16 Jul 2014

Cryptococcus gattii evolves as it spreads to temperate climates

Cryptococcus gattii, a virulent fungus that has invaded the Pacific Northwest is highly adaptive and warrants global "public health vigilance," according to a study by an international team led by the Translational Genomics Research Institute.

16 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

New research opens up potential new therapeutic targets for hard-to-treat food allergy

New research in Nature Genetics identifies a novel genetic and molecular pathway in the esophagus that causes eosinophillic esophagitis (EoE), opening up potential new therapeutic strategies for an enigmatic and hard-to-treat food allergy.

14 Jul 2014

Researchers identify new suppressor of cancer metastasis

Among patients with deadly cancers, more than 90 percent die because of metastatic spread of their disease. Looking to target a key pathway in order to interfere with the processes that lead to tumor spread, a research team led by Irwin H. Gelman, Ph.D., of Roswell Park Cancer Institute (RPCI) has identified a new suppressor of cancer metastasis that may point the way toward development of more effective treatments for prostate cancers and other malignant solid tumors.

14 Jul 2014

Genomic News and Research

Cypher Genomics, Illumina partner to facilitate development of genomic-based biomarkers

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

Research findings could lead to new approaches for treating schizophrenia

Saudi Arabian researchers detect genetic fragments of MERS-CoV in the air of camel barn

Findings point to biological mechanisms and pathways that may underlie schizophrenia

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

Genomics testing in action: an interview with Kevin Haar, CEO, Appistry

Study: Genetics plays major role in development of autism

Scientists reveal secrets of cell membrane proteins

TAZ represents a novel therapeutic target in NSCLC

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Research shows promise to speed up drug discovery for deadly diseases

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Cryptococcus gattii evolves as it spreads to temperate climates

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

New research opens up potential new therapeutic targets for hard-to-treat food allergy

Researchers identify new suppressor of cancer metastasis

New knowledge may expand treatments for patients with lung cancer

TCGA finds novel mutations in key cancer-causing pathway in lung adenocarcinoma

NCGR, Simbiot join forces to create new solutions for handling genomic data

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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