Medicine News and Research

RSS

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

Genzyme receives EC approval for Thyrogen product label expansion

Genzyme, a Sanofi company, today announced it has received European Commission approval of a product label expansion for the use of Thyrogen (thyrotropin alfa) with a wider irradiation dose range for postoperative thyroid remnant ablation.

10 Dec 2012

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Angiocidin, a novel tumor-inhibiting protein, has been shown to reduce acute myeloid leukemia (AML) cells in vivo by almost two-thirds in pre-clinical experiments.

10 Dec 2012

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

Obese women might be able to eliminate their increased risk for postmenopausal breast cancer by taking measures during perimenopause to prevent weight gain and to therapeutically control the metabolic effects of their obesity, according to the results of a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

10 Dec 2012

Sanofi announces new data from SAR302503 Phase II trial on myelofibrosis

Sanofi announced today new Phase II data showing that treatment with a novel, investigational, selective JAK2 inhibitor (SAR302503) reduced spleen size and improved constitutional symptoms in patients with intermediate-2 or high-risk primary or secondary myelofibrosis (MF), a hematologic malignancy with unmet medical needs.

10 Dec 2012

Researchers track emergence and global spread of healthcare-associated C. difficile

Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously thought. The spread and persistence of both epidemics were driven by the acquisition of resistance to a frontline antibiotic.

10 Dec 2012

Sanofi Pasteur’s IMOJEV vaccine against Japanese encephalitis is now available in Australia

Sanofi Pasteur, the vaccines division of Sanofi, announced today that IMOJEV vaccine against Japanese encephalitis (JE) is now available in Australia.

10 Dec 2012

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair.

10 Dec 2012

FoxP3 gene expression identifies ALS disease progression in 80% of patients

The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming print issue of The EMBO Molecular Medicine Journal.

10 Dec 2012

American Journal of Psychiatry publishes results from Successful Aging Evaluation study

Presently, there are about 40 million Americans over the age of 65, with the fastest-growing segment of the population over 80 years old. Traditionally, aging has been viewed as a period of progressive decline in physical, cognitive and psychosocial functioning, and aging is viewed by many as the "number one public health problem" facing Americans today.

9 Dec 2012

IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

Of the one million people each year who get hips and knees replaced, as many as 20,000 will get an infection in the new joint, a number that is expected to skyrocket in the next 20 years. Multispecialty physician teams need to work together to reduce disability, death and costs associated with the ever-growing number of these prosthetic joint infections, note the first guidelines on the topic being released by the Infectious Diseases Society of America (IDSA).

9 Dec 2012

More than 100 academic institutions to participate in Mathematics of Planet Earth 2013

More than 100 academic institutions and scholarly societies have joined in a major world-wide initiative: Mathematics of Planet Earth (MPE) 2013. This year-long effort will highlight the contributions made by mathematics in tackling global problems, including natural disasters such as hurricanes, earthquakes, and tsunamis; climate change; sustainability; and pandemics.

9 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Anti-seizure drug benefits women with severe morning sickness

Good news may be on the horizon for Kate Middleton, Duchess of Cambridge, and other women stricken with severe nausea and vomiting during pregnancy, thanks to the work of a University at Buffalo professor who is conducting research on a drug that is showing success treating pregnant women with this condition.

8 Dec 2012

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

For the first time, Brazil in 2013 will enter into a new type of public-private partnership that allows the nation to produce a generic version of the antiretroviral (ARV) drug atazanavir sulphate, which will be under patent through its producer Bristol-Myers Squibb until 2017, Inter Press Service reports.

8 Dec 2012

Treadmill test can accurately predict coronary artery disease in women over 65

Although there is a widespread belief among physicians that the exercise treadmill test (ETT) is not reliable in evaluating the heart health of women, UC Davis researchers have found that the test can accurately predict coronary artery disease in women over the age of 65. They also found that two specific electrocardiogram (EKG) indicators of heart stress during an ETT further enhanced its predictive power.

8 Dec 2012

WHO's decision to 'monitor' R&D 'deeply disappointing'

In this PLoS "Speaking of Medicine" blog post, Julien Potet and Katy Athersuch of Medecins Sans Frontieres' (MSF) Access Campaign say that the WHO's decision last week to "simply continue monitoring" the medical research and development (R&D) industry's ability to address the needs of people living in developing countries "by creating a global R&D 'observatory'" is "a deeply disappointing outcome that will not help re-shape priorities, increase funding or catalyze development of urgently needed new medical tools; at best it will only underscore further how badly these actions are needed."

8 Dec 2012

Baby boomers with liver cancer drive demand for liver transplantation

New research reveals that the greatest demand for liver transplantation due to hepatitis C (HCV)-related liver disease occurs among Americans born between 1941 and 1960. Findings in the December issue of Liver Transplantation, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD), suggest that continuing increased demand for transplantation is driven by the development of liver cancer in baby boomers with HCV, but that the demand may decrease as patients born in this time period continue to grow older.

7 Dec 2012

Roundup: Ga. 'provider fee' defeat could mean $430M less for Medicaid; Minn. health programs in line for $37M cut over fiscal cliff; Calif. stem cell board criticized

Just weeks before the 2013 General Assembly convenes, the state's provider fee, called a "bed tax" by some, remains a high-profile wild card -- one that could deal Georgia's hospital industry a crippling blow. If the fee is not renewed -- and anti-tax forces will oppose it -- the Medicaid system may lose $430 million-plus that the assessment now generates. That loss would swell the state's Medicaid financial shortfall, which is already about $400 million (Miller, 12/6).

7 Dec 2012

Results of Halaven Phase III study in metastatic breast cancer presented at 2012 CTRC-AACR SABCS

Results from the first large, global Phase III study of Halaven (eribulin mesylate) Injection in patients with early-stage metastatic breast cancer were presented today during the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.

7 Dec 2012

Medicine News and Research

Ibrutinib may effectively combat chronic lymphocytic leukemia

Genzyme receives EC approval for Thyrogen product label expansion

Angiocidin reduces acute myeloid leukemia cells in vivo by almost two-thirds in pre-clinical studies

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

Sanofi announces new data from SAR302503 Phase II trial on myelofibrosis

Researchers track emergence and global spread of healthcare-associated C. difficile

Sanofi Pasteur’s IMOJEV vaccine against Japanese encephalitis is now available in Australia

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

FoxP3 gene expression identifies ALS disease progression in 80% of patients

American Journal of Psychiatry publishes results from Successful Aging Evaluation study

IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

More than 100 academic institutions to participate in Mathematics of Planet Earth 2013

C5aRA treatment could be effective against periodontitis

Anti-seizure drug benefits women with severe morning sickness

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

Treadmill test can accurately predict coronary artery disease in women over 65

WHO's decision to 'monitor' R&D 'deeply disappointing'

Baby boomers with liver cancer drive demand for liver transplantation

Roundup: Ga. 'provider fee' defeat could mean $430M less for Medicaid; Minn. health programs in line for $37M cut over fiscal cliff; Calif. stem cell board criticized

Results of Halaven Phase III study in metastatic breast cancer presented at 2012 CTRC-AACR SABCS

Everything there is to know about biosimilars eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Latest News