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Investigators describe process by which apoE4 protein promotes development of Alzheimer's

Despite researchers' best efforts, no drug exists that can slow, halt or reverse the onslaught of Alzheimer's disease. A progressive and fatal neurodegenerative disorder, Alzheimer's has stolen the memories and livelihoods of millions-leaving patients and their families struggling to cope with the disease's devastating consequences. But today, scientists at the Gladstone Institutes propose a new research avenue that has the potential to change all that.

6 Dec 2012

IOM's Forum on Microbial Threats to take place from Dec.11-12

A two-day symposium will explore how much we have learned about new and re-emerging infectious diseases in the two decades since the Institute of Medicine issued a 1992 report pointing to major challenges in detecting and managing disease outbreaks.

6 Dec 2012

ASBD to host 6th Annual School of Oncoplastic Surgery in Dallas

The American Society of Breast Disease (ASBD) is merging art and medicine this week, by using clay sculpting and other techniques to teach surgeons new skills in breast cancer surgery and reconstruction.

6 Dec 2012

Case Western Reserve to receive funding through Healthy Growth grant program

Case Western Reserve University School of Medicine announced that it will receive funding through the Achieving Healthy Growth program within the Grand Challenges in Global Health initiative.

6 Dec 2012

Study questions value of coated, low-dose aspirin therapy

Roughly one-fifth of Americans take low-dose aspirin every day for heart-healthy benefits. But, based on either urine or blood tests of how aspirin blocks the stickiness of platelets - blood cells that clump together in the first stages of forming harmful clots - up to one third of patients are deemed unlikely to benefit from daily use. Such patients are called "aspirin resistant." Clots are the main cause of most heart attacks and strokes.

6 Dec 2012

Clinical trial to explore Lose It! App for postpartum weight loss

In a first-of-its-kind clinical trial, physician-researchers at University Hospitals (UH) Case Medical Center MacDonald Women's Hospital are exploring the use of "Lose It!," a free Smartphone application (app), for postpartum weight loss.

6 Dec 2012

Dendritic spines respond to and process synaptic inputs both chemically and electrically

It's the least understood organ in the human body: the brain, a massive network of electrically excitable neurons, all communicating with one another via receptors on their tree-like dendrites. Somehow these cells work together to enable great feats of human learning and memory. But how?

6 Dec 2012

Scientists evaluate two different strategies to treat Usher syndrome

After years of basic research, scientists at Johannes Gutenberg University Mainz (JGU) are increasingly able to understand the mechanisms underlying the human Usher syndrome and are coming ever closer to finding a successful treatment approach. The scientists in the Usher research group of Professor Dr. Uwe Wolfrum are evaluating two different strategies. These involve either the repair of mutated genes or the deactivation of the genetic defects using agents.

6 Dec 2012

TAU scientists win top prize in American Society of Human Genetics art competition

The fine arts and the exact sciences may appear an unlikely pair, but creativity is a crucial element in both. Prof. Karen Avraham and PhD candidate Shaked Shivatzki of Tel Aviv University's Sackler Faculty of Medicine embraced this truth when creating Hearing and Deafness: Structure and Sequence, their winning submission to the recent American Society of Human Genetics art competition.

6 Dec 2012

Western University research could lead to better treatments for PTSD and drug addiction

New research from Western University could lead to better treatments for Post-Traumatic Stress Disorder (PTSD) and drug addiction by effectively blocking memories. The research performed by Nicole Lauzon, a PhD candidate in the laboratory of Steven Laviolette at Western's Schulich School of Medicine & Dentistry has revealed a common mechanism in a region of the brain called the pre-limbic cortex, can control the recall of memories linked to both aversive, traumatic experiences associated with PTSD and rewarding memories linked to drug addiction.

6 Dec 2012

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

Researchers at Johns Hopkins Medicine in November surgically implanted a pacemaker-like device into the brain of a patient in the early stages of Alzheimer's disease, the first such operation in the United States. The device, which provides deep brain stimulation and has been used in thousands of people with Parkinson's disease, is seen as a possible means of boosting memory and reversing cognitive decline.

6 Dec 2012

New prenatal genetic test results in more clinically relevant information

A large, multi-center clinical trial led by researchers from Columbia University Medical Center (CUMC) shows that a new genetic test resulted in significantly more clinically relevant information than the current standard method of prenatal testing.

6 Dec 2012

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Even in Florida, where Republican leaders led the legal battle against Obamacare, there's recognition now that the state has to act fast to comply with the new law. ... After Nov. 6, Gov. Rick Scott had a change in tone. "Gov. Mitt Romney did not win the election. So, it's not an option to repeal Obamacare," he said. "So, my goal now is to focus on what's good for our citizens." But Republicans are having trouble convincing Tea Party activists that the fight is over.

6 Dec 2012

Sickle cell disease trial completes phase 3 patient enrollment

Emmaus Medical, Inc., a specialty pharmaceutical and regenerative medicine company, today announced the completion of patient enrollment for its phase 3 clinical trial to study L-glutamine as a treatment for sickle cell disease.

5 Dec 2012

Ponatinib offers new hope in drug-resistant leukemia

An investigational tyrosine kinase inhibitor, ponatinib, has shown high levels of activity in patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

5 Dec 2012

‘Old’ erythrocytes little problem in noncardiac surgery

Erythrocytes that have been stored for several weeks before use may not cause problems in patients who receive transfusions during noncardiac surgery, a large retrospective analysis suggests.

5 Dec 2012

Surprising discovery about physical properties of cancer cells

A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach - a liquid biopsy - that detects, measures, and evaluates cancer cells in blood.

5 Dec 2012

University of Chicago professor wins Manpei Suzuki International Prize for diabetes work

Graeme Ian Bell, PhD, the Louis Block Distinguished Service Professor of Medicine and Human Genetics and an investigator in the Kovler Diabetes Center at the University of Chicago, has been awarded the Manpei Suzuki International Prize for 2012 for his pioneering work in understanding the role of genetics in the diagnosis and treatment of diabetes.

5 Dec 2012

New metabolic biomarkers can detect risk of illnesses in advance

One of the big challenges of biomedicine is understanding the origin of illnesses in order to improve early detection and significantly increase recovery rates, as well as being able to do what CNIO researchers call preventive molecular medicine, which consists of identifying those individuals who have a greater molecular risk of suffering certain pathologies in order to prevent them.

5 Dec 2012

New method can generate stable human mesenchymal stem cells for bone engineering

Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die.

5 Dec 2012

Medicine News and Research

Investigators describe process by which apoE4 protein promotes development of Alzheimer's

IOM's Forum on Microbial Threats to take place from Dec.11-12

ASBD to host 6th Annual School of Oncoplastic Surgery in Dallas

Case Western Reserve to receive funding through Healthy Growth grant program

Study questions value of coated, low-dose aspirin therapy

Clinical trial to explore Lose It! App for postpartum weight loss

Dendritic spines respond to and process synaptic inputs both chemically and electrically

Scientists evaluate two different strategies to treat Usher syndrome

TAU scientists win top prize in American Society of Human Genetics art competition

Western University research could lead to better treatments for PTSD and drug addiction

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

New prenatal genetic test results in more clinically relevant information

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Sickle cell disease trial completes phase 3 patient enrollment

Ponatinib offers new hope in drug-resistant leukemia

‘Old’ erythrocytes little problem in noncardiac surgery

Surprising discovery about physical properties of cancer cells

University of Chicago professor wins Manpei Suzuki International Prize for diabetes work

New metabolic biomarkers can detect risk of illnesses in advance

New method can generate stable human mesenchymal stem cells for bone engineering

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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