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Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

Study pinpoints cell types linked to age-related macular degeneration

Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision.

25 Oct 2019

Researchers identify chemical signatures in blood and urine to measure dietary intake

Researchers at McMaster University have identified several chemical signatures, detectable in blood and urine, that can accurately measure dietary intake, potentially offering a new tool for physicians, dieticians and researchers to assess eating habits, measure the value of fad diets and develop health policies.

25 Oct 2019

Researchers discover how the body repairs damaged DNA

Researchers from the University of Copenhagen have made an extraordinary discovery in how the body repairs damaged DNA, which can lead to better understanding and management of diseases such as cancer.

25 Oct 2019

NYU Langone Health launches new molecular assay to identify patients with brain tumors

NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors.

24 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Gene linked to schizophrenia likely confers risk for illness

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.

24 Oct 2019

McMaster University research potentially offers new tool for assessing eating habits

24 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

Research suggests greater complexity in cellular protein movement

A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination.

23 Oct 2019

Study uses baker's yeast to show how genes interact to influence a surprising cellular outcome

Most diseases are complex--caused by faults in multiple genes--but studying how combinations of different genetic variants affect cellular traits is challenging.

23 Oct 2019

New CRISPR genome “prime editing” system

Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and up 89 percent of other genetic defects.

22 Oct 2019

SEPATH: New template to detect oncogenic viruses and bacteria in human DNA

A new study from the University of East Anglia describes a novel approach to detecting bacteria and viruses that may possibly be causing cancer. Many such associations have already been found, such as HPV (human papilloma virus) infection in cervical cancer, and Helicobacter pylori (H. pylori) in stomach cancer.

22 Oct 2019

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

Atrial fibrillation is the most common heart arrhythmia in humans. This condition increases the risk of heart failure, stroke, dementia and death, and current treatments have suboptimal efficacy and carry side effects.

21 Oct 2019

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

The All of Us Research Program has selected the HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, to evaluate the use of leading-edge DNA sequencing technologies that could someday improve diagnosis and treatment of many diseases, both common and rare.

18 Oct 2019

Researchers discover genes linked to sex ratio and male fertility in mice

One of the more recent trends among parents-to-be is the so-called gender reveal, a party complete with pink or blue cake to answer the burning question, "Is it a boy or girl?" After all, it's presumed that there's a 50-50 chance you'd have one or the other.

18 Oct 2019

Researchers develop new cheap method to identify aggressive tumors

Researchers at Karolinska Institutet in Sweden have developed a new cheap method that can identify highly heterogeneous tumors that tend to be very aggressive, and therefore need to be treated more aggressively. The technique is presented in the scientific journal Nature Communications.

18 Oct 2019

Vaping propylene glycol and vegetable glycerine may lead to lung inflammation

Researchers have found that using e-cigarettes with the e-liquid refills containing propylene glycol (PG) and vegetable glycerine (VG) may lead to inflammation of the lungs over a period of time. The results of the study titled, “Effects of Electronic Cigarette Constituents on the Human Lung: A Pilot Clinical Trial,” was published in the latest issue of the journal Cancer Prevention Research this week.

18 Oct 2019

Rare sex-specific brain cells found in male and female mice

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that governs both aggression and mating behaviors.

17 Oct 2019

Genome News and Research

Study finds molecular key to formation of mature and fully functioning T cells

Study pinpoints cell types linked to age-related macular degeneration

Researchers identify chemical signatures in blood and urine to measure dietary intake

Researchers discover how the body repairs damaged DNA

NYU Langone Health launches new molecular assay to identify patients with brain tumors

Scientists pinpoint epigenetic differences in the way lupus affects black women

Gene linked to schizophrenia likely confers risk for illness

McMaster University research potentially offers new tool for assessing eating habits

Genetic variations linked to declines in blood oxygen levels during sleep identified

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Research suggests greater complexity in cellular protein movement

Study uses baker's yeast to show how genes interact to influence a surprising cellular outcome

New CRISPR genome “prime editing” system

SEPATH: New template to detect oncogenic viruses and bacteria in human DNA

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

Researchers discover genes linked to sex ratio and male fertility in mice

Researchers develop new cheap method to identify aggressive tumors

Vaping propylene glycol and vegetable glycerine may lead to lung inflammation

Rare sex-specific brain cells found in male and female mice

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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