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How mothers transfer the DNA inside their mitochondria to their babies

A recent study has revealed how DNA inside the cell's powerhouse comes from the mother's side.

4 Oct 2019

Study sheds new light on transmission dynamics of HIV-1B virus in Indonesia

Research into the molecular phylogeny (evolutionary history) of the HIV-1B virus in Indonesia has succeeded in illuminating the transmission period and routes for three clades (main branches of the virus).

4 Oct 2019

Researchers identify new targets to treat fibrotic diseases

When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term - but bad when myofibroblast activation gets out of hand.

4 Oct 2019

ATCC launches new database of reference-quality genome sequences to aid biological research

ATCC launched its new ATCC Genome Portal, a publicly available database of reference-quality genome sequences matched to authenticated ATCC biological materials that will help researchers interpret and reproduce their results with confidence.

From American Type Culture Collection (ATCC) 4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

UC Davis researchers awarded $1.5 million NIH grant for CRISPR cancer treatment

What if, instead of killing cancer cells or cells about to become cancerous, you could deliver a repair package and fix them? UC Davis researchers have just been awarded $1.5 million from the National Institutes of Health to start work towards that goal.

3 Oct 2019

Mount Sinai researchers discover how DNA polymerase delta duplicates the genome

Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next. In a study published in Nature Structural & Molecular Biology, the team also reported how certain mutations can modulate the activity of this enzyme, leading to cancers and other diseases.

3 Oct 2019

Findings shed light on molecular reasons for early miscarriage

Researchers at Karolinska Institutet in Sweden have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells.

3 Oct 2019

Two cell mutations contribute to the development of acute myeloid leukemia

Sometimes the whole is greater than the sum of its parts. Researchers at Cold Spring Harbor Laboratory have discovered that two cell mutations, already harmful alone, enhance one another's effects, contributing to the development of the deadly blood cancer acute myeloid leukemia (AML).

3 Oct 2019

New leishmaniasis look-alike parasitic infection reported

A new study published online in the journal Emerging Infectious Diseases describes the appearance of a new protozoan infection carried by insects which causes symptoms that mimic the disease called visceral leishmaniasis, caused by a different parasite.

2 Oct 2019

Study examines daily distribution of drugs at major U.S. children's hospital

Too many hospitals provide medications according to the practicalities of their staffing schedules rather than the ideal dosing times for their patients, according to a new study led by experts at Cincinnati Children's.

1 Oct 2019

Findings could open up new research avenues into how heme tolerance occurs in humans

Most people have some idea of how important iron is to their health, but Iqbal Hamza, professor in Animal and Avian Sciences, has made his seventeen-year career at the University of Maryland all about the study of iron and heme trafficking and regulation in the body.

1 Oct 2019

Brazilian researchers identify new species of parasite in fatal case of visceral leishmaniasis

Brazilian researchers believe they have identified in patients treated at the University Hospital (HU) in Aracaju, state of Sergipe, a new species of parasite that can cause a disease similar to visceral leishmaniasis but is resistant to the treatments currently available.

1 Oct 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications.

30 Sep 2019

Research reveals new mechanism which could lead to premature aging in mother cells

Researchers from the University of Seville and the Andalusian Center of Molecular Biology and Regenerative Medicine, have discovered a new mechanism that makes it possible to understand premature aging in cells with asymmetrical cell division, as is the case with mother cells.

30 Sep 2019

New technique may help improve understanding, treatment of Crohn's disease

Scientists have developed a computer method that may help improve understanding and treatment of Crohn's disease, which causes inflammation of the digestive tract.

30 Sep 2019

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

Researchers at Queen Mary University of London and University College London have shown that using stem cells derived from patients could help find new treatments for a group of congenital muscular dystrophies.

30 Sep 2019

Deer can pass tuberculosis to humans, CDC warns

Tuberculosis or TB is a highly contagious infection that usually affects the lungs, but it can spread to other parts of the body, such as the spine and brain. Commonly caused by Mycobacterium tuberculosis, which can spread through the air from person to person.

30 Sep 2019