Genomic News and Research

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Genetic variants linked with greater risk for radiation-driven side effects in cancer patients

Key genetic variants may affect how cancer patients respond to radiation treatments, according to a study published this week in Nature Genetics.

8 Jul 2014

Pseudogenes may play key role in the discovery of new biomarkers

Dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism's survival and are the "last stop" for removal of genomic waste.

8 Jul 2014

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Researchers from Case Western Reserve University School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either protect against, or contribute to Alzheimer's disease risk.

8 Jul 2014

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Jeffrey Tyner, Ph.D., assistant professor of Cell, Developmental & Cancer Biology for Oregon Health & Science University (OHSU) and a researcher with OHSU's Knight Cancer Institute, has won a distinguished award from the American Association for the Advancement of Science (AAAS) for the development of a research program that more rapidly identifies the mutations driving a patient's cancer and accelerates development of precision treatments.

4 Jul 2014

CNIOA researchers update number of human genes to 19,000

How nutrients are metabolised and how neurons communicate in the brain are just some of the messages coded by the 3 billion letters that make up the human genome.

4 Jul 2014

Highmark, Horizon issued positive coverage policies for Afirma Gene Expression Classifier

Veracyte, Inc., a molecular diagnostics company pioneering the field of molecular cytology, today announced that two Blue Cross Blue Shield–affiliated organizations, Highmark Inc. and Horizon Blue Cross Blue Shield of New Jersey, have issued positive coverage policies for the company's Afirma Gene Expression Classifier (GEC).

3 Jul 2014

Findings provide new insights into the basic biology of stem cells

A team of researchers from the University of California, San Diego School of Medicine, Oregon Health & Science University and Salk Institute for Biological Studies has shown for the first time that stem cells created using different methods produce differing cells.

3 Jul 2014

Lung cancer patients could benefit from new 'QTA' technique

Lung cancer patients could receive more precise treatment, and their progress could be better tracked, using a new high-tech method of non-invasive medical imaging analysis, according to a study published today by the journal PLOS ONE.

3 Jul 2014

Eurofins Genomics, AmpTec sign co-marketing agreement for IVT-RNAs

Eurofins Genomics, international market leader in genomic services, and AmpTec, internationally recognized provider of RNA technology products, have agreed on non-exclusively co-marketing AmpTec's IVT-RNAs globally.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

UCLA receives $7.2 million grant to develop ways to diagnose rare genetic disorders

The David Geffen School of Medicine at UCLA is one of six institutions nationwide chosen by the National Institutes of Health to join their effort in tackling the most difficult-to-solve medical cases and develop ways to diagnose rare genetic disorders.

1 Jul 2014

Study uncovers new information on genes that may increase risk of cardiac arrhythmias

Two international research studies, both led by investigators affiliated with Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard, have uncovered new information about genes that may increase the risk of serious cardiac arrhythmias.

1 Jul 2014

Light-sensitive molecule enables noninvasive silencing of neurons

Optogenetics, a technology that allows scientists to control brain activity by shining light on neurons, relies on light-sensitive proteins that can suppress or stimulate electrical signals within cells. This technique requires a light source to be implanted in the brain, where it can reach the cells to be controlled.

30 Jun 2014

CNIO researchers identify over 40 genes that predict aggressiveness of melanoma

Researchers from the Spanish National Cancer Research Centre have discovered more than 40 genes that predict the level of aggressiveness of melanoma and that distinguish it from other cancers with a poor prognosis. The discovery, published in Cancer Cell, will help to identify unique aspects of melanoma that could contribute to determine the risk of developing metastasis in patients with this disease.

28 Jun 2014

Researchers identify microorganisms that may trigger diarrheal disease among children

In a finding that may one day help control a major cause of death among children in developing countries, a team of researchers led by faculty from the University of Maryland, College Park and the University of Maryland School of Medicine has identified microorganisms that may trigger diarrheal disease and others that may protect against it.

28 Jun 2014

Jackson Laboratory Cancer Center earns renewal of Cancer Center Support Grant from NCI

The Jackson Laboratory Cancer Center has once again earned the renewal of its Cancer Center Support Grant from the National Cancer Institute (NCI).

26 Jun 2014

Current sequencing protocols overlook DNA crucial to bacterial virulence

Genomic sequencing is supposed to reveal the entire genetic makeup of an organism. For infectious disease specialists, the technology can be used to analyze a disease-causing bacterium to determine how much harm it is capable of causing and whether or not it will be resistant to antibiotics.

26 Jun 2014

Researchers compare genome sequences of malaria vectors to investigate insecticide resistance

Researchers from LSTM have exploited a natural experiment created by insecticidal pressure to determine how the most important malaria vectors - A. gambiae s.s. and A. coluzzii - respond rapidly to environmental change.

26 Jun 2014

Gene in brain promotes kidney cancer, report researchers

A gene known to control brain growth and development is heavily involved in promoting clear cell renal cell carcinoma, the most common form of kidney cancer, researchers from Mayo Clinic in Florida are reporting.

25 Jun 2014

Genomic News and Research

Genetic variants linked with greater risk for radiation-driven side effects in cancer patients

Pseudogenes may play key role in the discovery of new biomarkers

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

CNIOA researchers update number of human genes to 19,000

Highmark, Horizon issued positive coverage policies for Afirma Gene Expression Classifier

Findings provide new insights into the basic biology of stem cells

Lung cancer patients could benefit from new 'QTA' technique

Eurofins Genomics, AmpTec sign co-marketing agreement for IVT-RNAs

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

UCLA receives $7.2 million grant to develop ways to diagnose rare genetic disorders

Study uncovers new information on genes that may increase risk of cardiac arrhythmias

Light-sensitive molecule enables noninvasive silencing of neurons

CNIO researchers identify over 40 genes that predict aggressiveness of melanoma

Researchers identify microorganisms that may trigger diarrheal disease among children

Jackson Laboratory Cancer Center earns renewal of Cancer Center Support Grant from NCI

Current sequencing protocols overlook DNA crucial to bacterial virulence

Researchers compare genome sequences of malaria vectors to investigate insecticide resistance

Gene in brain promotes kidney cancer, report researchers

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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