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AI tool can reduce the need for invasive diagnostic procedures in ulcerative colitis

When visiting a doctor, many patients prefer non-invasive procedures over invasive and potentially painful ones.

13 Dec 2021

Sarcopenia and COVID-19

The present study attempts to investigate if sarcopenia, which is a condition where there is loss of skeletal muscle mass and function, may result in poor clinical outcomes in COVID-19 patients.

13 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

An assessment of COVID-19 mortality risk using patient biomarker time series

A new study discusses the use of multiple biomarkers taken over the course of hospitalization in COVID-19 patients to determine the risk of mortality.

12 Dec 2021

Researchers discover why people with asthma have lower brain tumor risk

There's not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed.

11 Dec 2021

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

11 Dec 2021

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Despite preliminary supporting evidence that the dopaminergic agent bupropion might improve sexual desire for female cancer survivors, the NRG Oncology CC004 clinical trial determined that bupropion did not improve outcomes when compared to a placebo.

10 Dec 2021

Researchers explore role of FTO gene in the comorbidity of depression and obesity

Scientists from the University of Granada (UGR) have highlighted that the possible role attributed to the 'fat mass and obesity-associated' (FTO) gene in the comorbidity of depression and obesity can only be confirmed by conducting more studies involving individuals suffering from both diseases, together with more in-depth analysis of the different clinical subtypes of depression, as some are more prone to being accompanied by obesity than others.

9 Dec 2021

COVID-19 vaccine-related myocarditis in young people is mild and resolves quickly, research says

Most young people under the age of 21 who developed suspected COVID-19 vaccine-related heart muscle inflammation known as myocarditis had mild symptoms that improved quickly, according to new research published today in the American Heart Association’s flagship journal Circulation.

9 Dec 2021

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Scientists discuss the characteristics, diagnostic evaluations, and cardiac diagnoses in patients referred to a clinic designed for patients with PASC.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

A new medication has been added to the treatment options for children with moderate-to-severe asthma. In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11.

9 Dec 2021

UVA researchers uncover common link between lupus and macular degeneration

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

9 Dec 2021

Brain injury markers associated with dysregulated immunological responses in COVID-19

Study shows that during hospitalization, patients with COVID-19 demonstrated elevated NfL and GFAP in a severity-dependant manner, as well as evidence of ongoing active brain injury 4 months later.

8 Dec 2021

Consuming a diet of pro-inflammatory foods linked to frailty risk in middle-aged and older adults

Results of a study published in the American Journal of Clinical Nutrition indicate that regularly consuming a diet of pro-inflammatory foods (e.g., those rich in simple carbohydrates or in saturated fats) is associated with increased likelihood of developing frailty in middle-aged and older adults.

8 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Led by computational researchers from WEHI, in collaboration with The University of Queensland, Queensland University of Technology and Hospital Marcelino Champagnat in Brazil, the study used advanced spatial transcriptomic techniques to screen for genes associated with excessive inflammation in the lungs, a key indicator of severe COVID-19.

7 Dec 2021

Inflammation News and Research

AI tool can reduce the need for invasive diagnostic procedures in ulcerative colitis

Sarcopenia and COVID-19

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

An assessment of COVID-19 mortality risk using patient biomarker time series

Researchers discover why people with asthma have lower brain tumor risk

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Researchers explore role of FTO gene in the comorbidity of depression and obesity

COVID-19 vaccine-related myocarditis in young people is mild and resolves quickly, research says

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

UVA researchers uncover common link between lupus and macular degeneration

Brain injury markers associated with dysregulated immunological responses in COVID-19

Consuming a diet of pro-inflammatory foods linked to frailty risk in middle-aged and older adults

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

A promising new therapeutic target for kidney disease

Cochlear implant recipients develop new bone formation that leads to long-term residual hearing loss

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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