Genes News and Research

RSS

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Exploring the relationship between stem cells and COVID-19

Though COVID-19-related stem cell clinical research is still in its infancy, stem cell treatment offers extensive clinical application possibilities and a far-reaching relevance thanks to ongoing exploration of stem cell clinical research and data mining.

14 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Researchers identify gene variant that protects against severe COVID-19

An international metastudy led by researchers at Karolinska Institutet in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

13 Jan 2022

Study shows that key parts of human immunity are shared in bacteria

The human immune system, that marvel of complexity, subtlety, and sophistication, includes a billion-year-old family of proteins used by bacteria to defend themselves against viruses, scientists at Dana-Farber Cancer Institute and in Israel have discovered.

13 Jan 2022

Investigating the presence of human rRNA in the SARS-CoV-2 genome

In a new study, a team of researchers investigated the existence of SARS-CoV-2-host chimeric RNA and described two novel human-derived genomic insertions present in the circulating variants of SARS-CoV-2.

13 Jan 2022

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

Defective gene in blood cancers could be treated with already available drugs

A defective gene, normally found in blood cancers, could be treated with drugs already available for cancers with similar gene defects, scientists at Queen’s University Belfast and the University of Birmingham have revealed.

13 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

The zoonotic potential of epidemic porcine deltacoronavirus

The present state of knowledge about the genesis, evolution, cross-species transmission, and zoonotic potential of PDCoV is the subject of a review published in the journal Pathogens, which was conducted in a combined effort by researchers from Heilongjiang Bayi Agricultural University and Ohio State University.

13 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

The iMolecule group from Skoltech has developed an artificial intelligence-driven solution that uses data on the structure of RNA or DNA molecules to identify sites on them where interaction with potential drug candidates can occur.

11 Jan 2022

New insights into molecular mechanisms that underpin the body's natural defenses against skin cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer.

11 Jan 2022

Genes News and Research

Researchers investigate the role of a key component of the circadian clock in heart disease

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Cannabidiol may improve innate immune response against SARS-CoV-2

Study provides valuable insight into the developmental origins of schizophrenia

Exploring the relationship between stem cells and COVID-19

Virus-like particles as delivery vehicles for gene-editing

Researchers identify gene variant that protects against severe COVID-19

Study shows that key parts of human immunity are shared in bacteria

Investigating the presence of human rRNA in the SARS-CoV-2 genome

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

Defective gene in blood cancers could be treated with already available drugs

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

The zoonotic potential of epidemic porcine deltacoronavirus

Long-term use of blood pressure medication could be contributing to kidney damage

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

New insights into molecular mechanisms that underpin the body's natural defenses against skin cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo