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Preclinical studies show effectiveness of targeted therapy for glioblastoma

The targeted therapy onalespib has shown effectiveness in preclinical studies of glioblastoma by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Nov 2017

Production of nitric oxide crucial for stem cell mobilization and differentiation

Nathan Bryan, PH.D., one of the nation's leading experts on critically important role of nitric oxide in health and disease prevention, told attendees of the Pacific Regenerative Medicine 2017 Conference this morning that, "Stem cells are the future of medicine and are required for our body to heal itself; however, their success depends on the body producing enough nitric oxide to support their healing properties.

2 Nov 2017

Researchers discover mechanism that controls release of molecules involved in inflammatory diseases

In a recent study published in Cell Reports, a research team led by Colin Adrain, from the Instituto Gulbenkian de Ciência, discovered the mechanism that controls the release of important molecules that trigger the inflammatory response during the clearance of infections.

2 Nov 2017

GHIT Fund announces US$16.7 million to support development of new drugs, vaccines and diagnostics

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced US$16.7 million to support development of new compounds for fighting malaria and tuberculosis, a leishmaniasis vaccine and drug, and a treatment for a long-ignored flesh-eating infection.

31 Oct 2017

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Stem cell therapy has great potential for curing cartilage damage. However, it has remained unclear whether stem cells are responsible for regeneration or whether they trigger the process.

31 Oct 2017

Studying the nanomechanical properties of aging and cancerous cells using AFM

An interview with Prof. Igor Sokolov, Tufts University conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 31 Oct 2017

Artificial beta cells could be first step to new treatment for diabetes

Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion.

30 Oct 2017

Researchers produce 3D map of molecular 'scaffold' known to play key role in cancers

Researchers have produced the first three-dimensional (3D) map of a molecular 'scaffold' called SgK223, known to play a critical role in the development and spread of aggressive breast, colon, and pancreatic cancers.

30 Oct 2017

Study demonstrates beneficial effects of calorie-restricted diet in mice

Caloric restriction diets have been associated with various health benefits, but their effects on the skin have not been previously demonstrated. Research conducted at the University of São Paulo (USP) in Brazil shows that controlling calories helps mice live longer, although it reduces the reserves of fat in adipose tissue needed to keep the body warm.

30 Oct 2017

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

The mechanism of how cells work is key to understanding how tumours metastasize as well as tissue regeneration and other bodily functions. The process of mechanotransduction, or how a cell converts a physical stimuli into an electrical response is fundamental to these understandings.

From AXT Pty Ltd 30 Oct 2017

Researchers isolate new molecule suitable for control of contact allergies

Researchers from the University of Bonn have isolated a molecule that is suitable for the control of contact allergies. The study illuminates a central immune mechanism, which may also play a role in other inflammatory diseases such as arthritis or arteriosclerosis.

30 Oct 2017

Common factors that could change your PSA test results

Most men in their 50s, who face an increasing risk of prostate cancer as they age, are familiar with the common screening exam known as the prostate specific antigen (PSA) test. But many are less familiar with how the test works and why different factors, such as prescription medications and infections, can influence the test results.

28 Oct 2017

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

CureVac AG, a fully-integrated biotechnology company pioneering mRNA-based drugs, today announced it has initiated a Phase I study assessing the intratumoral application of its novel RNAdjuvant technology in patients with superficial solid tumors that are easily accessible for repeated intratumoral injections. RNAdjuvant is designed to amplify the scope and quality of an immune response when used alone or in combination with other immune therapies.

28 Oct 2017

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established the synthesis of a member compound, which is especially promising in killing pancreatic cancer stem cells.

28 Oct 2017

Newly patented formulation based on nanotechnology will offer neuropathic pain relief

The company GB Sciences Inc. has obtained the exclusive global worldwide intellectual property license for this innovative solution, which is based on nanotechnology.

28 Oct 2017

Novel molecule holds potential to become part of successful HIV vaccine

Researchers at the University of Maryland and Duke University have designed a novel protein-sugar vaccine candidate that, in an animal model, stimulated an immune response against sugars that form a protective shield around HIV. The molecule could one day become part of a successful HIV vaccine.

27 Oct 2017

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.

27 Oct 2017

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Researchers at Linköping University in Sweden have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves.

27 Oct 2017

Scientists define molecular mechanism that triggers pump-induced disease

Researchers at Texas Tech University Health Sciences Center investigated a pump-induced disease and defined the molecular mechanism that triggers it. The study, "On the effect of hyperaldosteronism-inducing mutations in Na/K pumps," was published in the October issue of the Journal of General Physiology.

26 Oct 2017

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors - changes in gene expression versus an alteration in the genetic code -- play an important role.

26 Oct 2017

Molecule News and Research

Preclinical studies show effectiveness of targeted therapy for glioblastoma

Production of nitric oxide crucial for stem cell mobilization and differentiation

Researchers discover mechanism that controls release of molecules involved in inflammatory diseases

GHIT Fund announces US$16.7 million to support development of new drugs, vaccines and diagnostics

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Studying the nanomechanical properties of aging and cancerous cells using AFM

Artificial beta cells could be first step to new treatment for diabetes

Researchers produce 3D map of molecular 'scaffold' known to play key role in cancers

Study demonstrates beneficial effects of calorie-restricted diet in mice

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

Researchers isolate new molecule suitable for control of contact allergies

Common factors that could change your PSA test results

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Newly patented formulation based on nanotechnology will offer neuropathic pain relief

Novel molecule holds potential to become part of successful HIV vaccine

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Scientists define molecular mechanism that triggers pump-induced disease

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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