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New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

A new study led by researchers at Harvard Medical School and the Harvard T.H. Chan School of Public Health has identified some of the first known inherited genetic variants that significantly raise a person's likelihood of developing clonal hematopoiesis, an age-related white blood cell condition linked with higher risk of certain blood cancers and cardiovascular disease.

12 Jul 2018

Research reveals new gears in the circadian clock

A long-studied factor controlling human sleep cycles actually has two forms, one that keeps a key protein stable and another that promotes its degradation.

12 Jul 2018

Study identifies cost-effective strategy to treat nail fungus using nanotechnology

Onychomycosis, a nail fungus that causes nail disfigurement, pain, and increased risk of soft tissue infection, impacts millions of people worldwide. There are several topical antifungal treatments currently available; however, treatment failure remains high due to a number of factors.

11 Jul 2018

Study uncovers process that neutralizes tumor cells

Researchers from the University of California San Diego have identified an unexpected mechanism that could help determine whether a cancer patient will respond to immunotherapy.

11 Jul 2018

Cellular 'garbage disposal' may actually work on some of the proteins to neuronal development

Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.

11 Jul 2018

Researchers reveal why CRISPR gene editing sometimes fails to work

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.

11 Jul 2018

Inhibiting immune-regulating molecule could prevent or reverse renal injury, research shows

Special cells called podocytes aid the kidneys as they clean the blood and balance the body's fluid levels. Podocytes filter blood as it passes through the cells' foot-like projections they are named for, interwoven like the fingers of clasped hands.

11 Jul 2018

Study: Eating Mediterranean-type diet could reduce bone loss in osteoporosis patients

Eating a Mediterranean-type diet could reduce bone loss in people with osteoporosis - according to new research from the University of East Anglia.

11 Jul 2018

Researchers find ATM protein that can trigger production of antioxidants

One reason we're supposed to eat a variety of colorful fruits and vegetables is because they contain nutritious compounds called antioxidants.

11 Jul 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Patients who suffer from Aspirin Exacerbated Respiratory Disease often experience an additional allergic reaction when drinking alcohol, including nasal congestion, wheezing, and a runny nose.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

New approach could greatly enhance people's long-term tolerance for transplants

Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant.

10 Jul 2018

Type 1 diabetes patients five times more likely to end up in ER or hospital after a gap in health insurance

For a million American adults, living with type 1 diabetes means a constant need for insulin medication, blood sugar testing supplies and specialized care, to keep them healthy and prevent a crisis that could end up in an emergency room, a hospital bed or death.

10 Jul 2018

Bruker launches innovative iProbe HRMAS for biomolecular, materials and clinical research

At EUROMAR 2018 conference (www.euromar2018.org), Bruker announced the iProbe HRMAS, which now enables full automation of high-resolution magic angle spinning NMR.

From Bruker BioSpin Group 10 Jul 2018

Geography may be destiny in end-of-life care for cancer patients

When it comes to how much end-of-life care a patient with cancer receives, geography may, indeed, be destiny, according to new research led by Harvard Medical School that found striking differences in terminal care across different parts of the country.

10 Jul 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

Preventative HIV vaccines induce robust, comparable immune responses in humans and monkeys

More than three decades after the identification of the human immunodeficiency virus, scientists are still working to develop a preventative vaccine that could finally put an end to the epidemic for which there are nearly two million new infections each year.

9 Jul 2018

Step towards an HIV/AIDS vaccine

There has been a four decades long challenge to develop a vaccine against the deadly HIV virus that causes AIDS. Last Saturday the research bore fruit when a team of scientists announced that a trial drug has shown immune response in humans and also protected laboratory monkeys from HIV infection.

9 Jul 2018

Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Medical School News and Research

New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

Research reveals new gears in the circadian clock

Study identifies cost-effective strategy to treat nail fungus using nanotechnology

Study uncovers process that neutralizes tumor cells

Cellular 'garbage disposal' may actually work on some of the proteins to neuronal development

Researchers reveal why CRISPR gene editing sometimes fails to work

Inhibiting immune-regulating molecule could prevent or reverse renal injury, research shows

Study: Eating Mediterranean-type diet could reduce bone loss in osteoporosis patients

Researchers find ATM protein that can trigger production of antioxidants

Mature kidney podocytes for developing cell therapies and drug discovery

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Researchers use genome editing to reduce cholesterol levels in animal model

New approach could greatly enhance people's long-term tolerance for transplants

Type 1 diabetes patients five times more likely to end up in ER or hospital after a gap in health insurance

Bruker launches innovative iProbe HRMAS for biomolecular, materials and clinical research

Geography may be destiny in end-of-life care for cancer patients

Study identifies constellation of metabolites linked to ME/CFS

Preventative HIV vaccines induce robust, comparable immune responses in humans and monkeys

Step towards an HIV/AIDS vaccine

Widespread transfer of genes between species appears to be key driver of evolution

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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