Membrane News and Research

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Scientists stop age-related decline in an entire organ

As people age, their cells become less efficient at getting rid of damaged protein - resulting in a buildup of toxic material that is especially pronounced in Alzheimer's, Parkinson's disease, and other neurodegenerative disorders.

10 Aug 2008

Molecular bridge serves as a tether for a cell's nucleus

A cell's nucleus - home of it its most precious contents - is a delicate envelope that, without support, is barely able to withstand the forces that keep it in place. Now, researchers have discovered a network of molecules in the nuclear membrane that provide the nucleus with rigidity and also facilitate a previously undiscovered form of communication between the cell's nucleus and its cytoplasm.

8 Aug 2008

Scientists develop high-performance, hemispherical "eye" camera

By combining stretchable optoelectronics and biologically inspired design, scientists have created a remarkable imaging device, with a layout based on the human eye.

6 Aug 2008

Some bacteria steal iron from their human hosts - discovery could lead to new ways to fight tuberculosis

Like their human hosts, bacteria need iron to survive and they must obtain that iron from the environment. While humans obtain iron primarily through the food they eat, bacteria have evolved complex and diverse mechanisms to allow them access to iron.

31 Jul 2008

An unsuspected weakness in tuberculosis - potential drug target

With antibiotic resistance on the rise, tuberculosis is emerging as a bigger global health threat than ever before.

31 Jul 2008

microRNA may influence development of alcohol tolerance

In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species.

30 Jul 2008

New antibiotics to fight MRSA

A new paper by Shahriar Mobashery, Navari Family Professor in Life Sciences at the University of Notre Dame, and researchers in his lab provides important insights into promising new antibiotics aimed at combating MRSA.

28 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008

Tethered bilayer membrane may unlock secrets of early-stage Alzheimer's

Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer's disease actually impairs a neuron's structure and function.

23 Jul 2008

Discovery of cells for spinal-cord repair

A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.

22 Jul 2008

HIV-I damages the immune system early than originally thought

New research into the earliest events occurring immediately upon infection with HIV-I shows that the virus deals a stunning blow to the immune system earlier than was previously understood. According to scientists at Duke University Medical Center, this suggests the window of opportunity for successful intervention may be only a matter of days - not weeks - after transmission, as researchers had previously believed.

19 Jul 2008

Scientists map anatomy of a membrane protein

In an Australian first, scientists at Sydney's Centenary Institute have mapped the anatomy of a membrane protein. This exciting discovery has the potential to turn the way we discover new drugs on its head and reduce the development time for new treatments.

14 Jul 2008

Advances in RNA research

RNA, the transporter of genetic information within the cell, has emerged from the shadow of DNA to become one of the hottest research areas of molecular biology, with implications for many diseases as well as understanding of evolution. But the field is complex, requiring access to the latest equipment and techniques of imaging, gene expression analysis and bioinformatics, as well as cross-pollination between multiple scientific disciplines.

10 Jul 2008

Researchers measure movements smaller than one-billionth of a meter in ion channels

Each thought or action sends a million electrical signals pulsing through your body. At the heart of the process of generating these electrical impulses is the ion channel.

10 Jul 2008

New understanding of how malaria parasite survives in and totally changes red blood cells

A new study-done on a scale an order of magnitude greater than anything previously attempted in the field of malaria-has uncovered an arsenal of proteins produced by the malaria parasite that allows it to hijack and remodel human red blood cells, leaving the oxygen-carrying cells stiff and sticky.

8 Jul 2008

Discovery of new function for an old enzyme in sialidosis

The lack of a single protein usually thought of as a run-of-the-mill enzyme that helps to recycle molecules in cells causes an incurable and often fatal disease of children, according to St. Jude Children's Research Hospital investigators.

7 Jul 2008

Pregnancy rates decrease and miscarriages increase when a father is over 35

Pregnancy rates decrease and miscarriages increase when a father is over 35 years of age, a scientist will tell the 24th annual conference of the European Society of Human Reproduction and Embryology (Monday 7 July). Dr. Stephanie Belloc, of the Eylau Centre for Assisted Reproduction, Paris, France, will say that this is the first time that such a strong paternal effect on reproductive outcomes has been shown.

6 Jul 2008

Researchers solve structure of proteins known as sodium glucose co-transporters

Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells.

4 Jul 2008

Breast cancer: How tumor cells break free and form metastases

When tumor cells acquire the capacity to move around and invade other tissues, there is a risk of metastases and cancer treatment becomes more difficult. At the Institut Curie, CNRS Director of Research Philippe Chavrier and his group have just discovered how breast cancer cells break the bonds that tether them to the tumor. The basement membrane around the mammary gland is a barrier to the spread of cancer cells. Three proteins in the tumor cells transport enzymes needed to perforate this barrier, and another protein puts these enzymes in the right place.

4 Jul 2008

New discovery a step towards better diabetes treatment

In the July 2nd issue of the prestigious journal Cell Metabolism Uppsala scientists are presenting new findings that shed light on the processes that determine the release of the blood sugar-lowering hormone insulin.

1 Jul 2008