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Wayne State researchers win NIH grant to uncover new antibiotic targets

A research team from Wayne State University has received a $1.85 million grant from the National Institute of General Medical Sciences of the National Institutes of Health for the project "Mechanisms of Non-Shine-Dalgarno Translation Initiation."

26 Oct 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

IBN researchers create DNA technology with two new genetic alphabets

Just like how alphabets are strung together to form words, our DNA is also strung together by alphabets to encode proteins. Our DNA contains only 4 natural genetic alphabets - A, C, G and T, which hold the blueprint for the production of proteins that make our bodies work.

26 Oct 2017

Timing of DNA damage within checkpoints matters to a cell's fate, study reports

DNA damage occurs routinely within your cells due to sun exposure, smoking and sometimes during the normal process of making new DNA.

26 Oct 2017

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Very little is still known about how neurons can be generated from stem cells. Researchers at the University Medical Center of Johannes Gutenberg University Mainz have now developed a promising technique that will facilitate the differentiation of stem cells into neurons. This even enables them to accelerate the maturation process.

26 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

Pre-clinical study reports promising step forward in search for non-addictive painkillers

A pre-clinical study led by Indiana University scientists reports a promising step forward in the search for pain relief methods without the addictive side effects behind the country's current opioid addiction crisis.

25 Oct 2017

Scientists develop physiological approach to restore gut’s ecosystem in various diseases

The trillions of microbes living in a mammal's intestine play an important role in the host's metabolism and immunity. The composition of microbiota is maintained by antimicrobial proteins secreted from intestinal cells.

24 Oct 2017

New molecule could become first treatment against chemotherapy-induced neuropathy

IDIBELL Researchers of the Neuro-Oncology Unit of Bellvitge University Hospital - Catalan Institute of Oncology, led by Dr. Jordi Bruna, have successfully tested a new molecule capable of preventing the development of peripheral neuropathy induced by chemotherapy in cancer patients, especially in colon cancer cases, the third most common neoplasm in the world.

24 Oct 2017

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Brazilian scientists examine how benzopyrene can cause cancer

Benzo[a]pyrene is a potent carcinogen and mutagen present in cigarette smoke, automotive exhaust, burnt wood fumes, barbecued and smoked meat etc.

23 Oct 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Research provides insight on Y-shape in proteins associated with glaucoma

So unheard of was what researchers discovered in a protein associated with glaucoma that for over two years they ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially saw.

23 Oct 2017

Serum metabolites linked to NAFLD may be heritable, research shows

Serum metabolites associated with nonalcoholic fatty liver disease may be heritable, according to research presented this week at The Liver Meeting - held by the American Association for the Study of Liver Diseases.

20 Oct 2017

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked.

20 Oct 2017

Researchers discover new function in gene-regulatory protein

Researchers at Umeå and Stockholm universities in Sweden and Johns Hopkins University School of Medicine in the US have published a new study in the journal Molecular Cell.

20 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

New RNA switch achieves gene activation thousands of times better than nature

If scientists could precisely regulate gene expression, they could turn off the genes responsible for illness and disease and turn on those that enhance health and the immune system.

19 Oct 2017

New research provides insights into role of key cancer gene

New research represents a promising step towards better understanding of a key cancer gene. A long-running collaboration between researchers at the Babraham Institute, Cambridge, and the AstraZeneca IMED Biotech Unit reveals new insights into how the PTEN gene may control cell growth and behavior and how its loss contributes to the development and advancement of certain cancers.

19 Oct 2017

Molecule News and Research

Wayne State researchers win NIH grant to uncover new antibiotic targets

New enzyme may one day enable genome surgery that erases harmful mutations

IBN researchers create DNA technology with two new genetic alphabets

Timing of DNA damage within checkpoints matters to a cell's fate, study reports

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Researchers find rare genetic variants that may help explain longevity in some CF patients

Pre-clinical study reports promising step forward in search for non-addictive painkillers

Scientists develop physiological approach to restore gut’s ecosystem in various diseases

New molecule could become first treatment against chemotherapy-induced neuropathy

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Brazilian scientists examine how benzopyrene can cause cancer

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

Researchers discover new regulatory role for protein that links diet and disease

Research provides insight on Y-shape in proteins associated with glaucoma

Serum metabolites linked to NAFLD may be heritable, research shows

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Researchers discover new function in gene-regulatory protein

Small RNA molecules trigger cancer cells to commit suicide

New RNA switch achieves gene activation thousands of times better than nature

New research provides insights into role of key cancer gene

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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