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International trial shows better option for treating people with inoperable anal cancer

People with inoperable anal cancer treated with carboplatin-paclitaxel had fewer complications and lived longer than those who received another chemotherapy that has been more often administered.

24 Jun 2020

Researchers examine deintensification of diabetes treatment for older adults with limited life expectancy

One in four people aged 65 or older has diabetes. The disease is the seventh leading cause of death in the United States and a major contributor to heart disease.

24 Jun 2020

Making AI systems to diagnose more like a doctor

Artificial intelligence (AI) is an important innovation in diagnostics, because it can quickly learn to recognize abnormalities that a doctor would also label as a disease.

24 Jun 2020

A 'quick and easy' COVID-19 test developed for population-scale screening

Global endeavors to fight the Covid-19 pandemic heavily rely on accurate, fast and frequent tests for the coronavirus SARS-CoV-2 - "test, test, test", as the World Health Organization has bluntly put it.

24 Jun 2020

A stereo sense of smell subconsciously guides navigation in humans

"If in doubt, always follow your nose," said Gandalf in The Lord of the Rings. Despite Gandalf's advice, humans tend to regard themselves as "microsmatic" - having a poor sense of smell.

24 Jun 2020

New project aims to track coronavirus using human waste

Recent studies in the Netherlands and other places have shown that the presence of SARS-Coronavirus-2, or the novel coronavirus, can be detected in human waste.

24 Jun 2020

A metabolic enzyme drives B cell lymphomas and could be a potential drug target

Scientists at the Sloan Kettering Institute have found that increased activity of a normal metabolic enzyme can lead to cancer. The enzyme, SHMT2, is a driver of a large portion of B cell lymphomas and could be a potential drug target.

24 Jun 2020

Study finds entry point for curbing the evolution of antibiotic resistance

The team of Professor Tobias Bollenbach from the Institute for Biological Physics at the University of Cologne has published a study on a new approach to improving the effectiveness of antibiotics in bacterial infections.

24 Jun 2020

Increase in sedentary behavior can contribute to cardiovascular health deterioration

The adverse side effects of the social isolation measures implemented to combat COVID-19 include an increase in sedentary behavior and physical inactivity, which can contribute to a deterioration in cardiovascular health even in the short term. Older people and people with chronic diseases tend to be most affected.

24 Jun 2020

High deductible health plans are widening racial health gaps, study says

First-of-its-kind study finds that black cancer survivors on these plans are far more likely to struggle to afford health care and medicine than their white counterparts, while black and white cancer survivors on other types of plans are equally unlikely to face these challenges.

24 Jun 2020

School nurses critical to safe reopening of schools

Sudden school closures in the United States were undertaken to reduce COVID-19 transmission this spring. Those closures were not typical, and how and when schools reopen will create a set of new norms, with unique stressors for students, families, school personnel, and communities.

24 Jun 2020

Study identifies world's first genetic and environmental risk factor for common childhood epilepsy

A new study of childhood epilepsy has identified the world's first environmental risk factor for the disease - maternal smoking in pregnancy, and discovered a new genetic association with the condition, pointing to potential new treatments for the disease.

24 Jun 2020

Tiny protein in mitochondria has a big impact on health and longevity, study shows

A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein has a big impact on health and longevity in both animals and humans.

24 Jun 2020

New assay rapidly tests SARS-CoV-2 neutralization and screens antivirals

Researchers at the University of Texas Medical Branch, Galveston, have developed a new platform that can rapidly test neutralizing antibody activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and perform high-throughput screening of potential antiviral agents.

24 Jun 2020

Effective neutralization of SARS-CoV-2 by synthetic nanobodies targeting the spike protein

In their recent bioRxiv paper, a multinational group of researchers reported rapid isolation and characterization of nanobodies from a synthetic library (known as sybodies) that target the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein – with a strikingly high neutralization ability.

24 Jun 2020

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

A seminal study by US researchers, currently available on the bioRxiv* preprint server, demonstrates how structure-based design can be efficiently employed to develop molecular probes targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike and its domains, with possible future use in diagnostics, treatment and vaccine development.

24 Jun 2020

Research News and Research

International trial shows better option for treating people with inoperable anal cancer

Researchers examine deintensification of diabetes treatment for older adults with limited life expectancy

Making AI systems to diagnose more like a doctor

A 'quick and easy' COVID-19 test developed for population-scale screening

A stereo sense of smell subconsciously guides navigation in humans

New project aims to track coronavirus using human waste

A metabolic enzyme drives B cell lymphomas and could be a potential drug target

Study finds entry point for curbing the evolution of antibiotic resistance

Increase in sedentary behavior can contribute to cardiovascular health deterioration

High deductible health plans are widening racial health gaps, study says

School nurses critical to safe reopening of schools

Study identifies world's first genetic and environmental risk factor for common childhood epilepsy

Tiny protein in mitochondria has a big impact on health and longevity, study shows

New assay rapidly tests SARS-CoV-2 neutralization and screens antivirals

Effective neutralization of SARS-CoV-2 by synthetic nanobodies targeting the spike protein

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

Common cancer treatments do not worsen COVID-19 infection, study finds

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

Tau protein modifications may be linked to heterogeneity in Alzheimer’s disease

Researchers develop a noninvasive technology to destroy cancer cells

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