Inflammation News and Research

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Irregular body clock plays key role in driving inflammation in the immune cells, research shows

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

24 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Since they hit the market, e-cigarettes have been touted as a safe alternative to tobacco cigarettes for adult smokers.

24 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

A new combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson's disease-afflicted brain cells, according to a Northwestern Medicine study published in Neuron.

23 Nov 2021

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

New research suggests that SARS-CoV-2 infection can directly target and cause cellular damage to the adrenal glands.

23 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

22 Nov 2021

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

No one will disagree that an active lifestyle is good for you, but it remains unclear how physical activity improves brain health, particularly in Alzheimer's disease.

22 Nov 2021

Giving social support to others may play an important role in health

When it comes to your health, being willing to give social support to your spouse, friends and family may be just as important as receiving assistance, a new study suggests.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

A trio of proteins found to drive inflammation in psoriasis

About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies - and for many, the relief is temporary.

21 Nov 2021

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices.

21 Nov 2021

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body's cytotoxic T-cell-based response to tumors.

21 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Severe COVID-19 patients have significantly higher NK and T cell frequency

A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity.

18 Nov 2021

Long-term glycemic levels predict the risk of COVID-19 severity among diabetics

People with type 2 diabetes who contract COVID-19 are nearly 50% more likely to wind up in intensive care if they have poorly managed their blood sugar levels over the long-term than those with better long-term glycemic control, according to a study using anonymized health care data.

18 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

Study identifies possible link between psychological stress and Crohn's disease flare-ups

A possible link between psychological stress and Crohn's disease flare-ups has been identified by a McMaster University-led study.

18 Nov 2021

Tea and coffee consumption associated with lower risk of stroke and dementia

Researchers investigate the impact of coffee and tea separately and in combination on the risk of stroke and dementia.

18 Nov 2021

Inflammation News and Research

Irregular body clock plays key role in driving inflammation in the immune cells, research shows

Experimental compound reduces diabetic complications in mice

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

Giving social support to others may play an important role in health

Monitoring cellular metabolism for NAFLD/NASH liver disease research

A trio of proteins found to drive inflammation in psoriasis

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Severe COVID-19 patients have significantly higher NK and T cell frequency

Long-term glycemic levels predict the risk of COVID-19 severity among diabetics

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Study identifies possible link between psychological stress and Crohn's disease flare-ups

Tea and coffee consumption associated with lower risk of stroke and dementia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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