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Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

In new evidence-based guidelines, the American Gastroenterological Association recommends non-invasive biomarkers as a first-line strategy for monitoring many patients with ulcerative colitis (UC).

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Fetal cell program appears to protect against acute myeloid leukemia

During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

How the human gut microbiota is shaped by diet

A new study in the journal Best Practice & Research Clinical Gastroenterology aimed to summarize the impact of specific nutrients as well as diets on the gut microbiota as well as the future perspectives of using diet as a therapeutic microbiome modulator.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

Activating or deactivating drugs with the help of light

Scientists at the Paul Scherrer Institute PSI have used the Swiss X-ray free-electron laser SwissFEL and the Swiss Light Source SLS to make a film that could give a decisive boost to developing a new type of drug.

20 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Protein C News and Research

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Step-by-step process of rewiring cells to generate germ cell precursors

First molecular biomarker for acquired generalized lipodystrophy discovered

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

First fully human ovarian organoids provide insights about female reproductive health and disease

Fetal cell program appears to protect against acute myeloid leukemia

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

HKU research advances understanding of the fundamental biological processes of gene regulation

How the human gut microbiota is shaped by diet

Structure of DREADD designer receptor could pave the way for creating next generation tools

Research reveals regional differences in the spread of Japan's two main ancestral groups

Activating or deactivating drugs with the help of light

Genome editing prevents hypertrophic cardiomyopathy in mice

Can COVID-19 vaccinations cause miscarriage in pregnant women?

Gut dysbiosis and sepsis susceptibility among pregnant women

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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