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Warning against colloids in fluid resuscitation

Hydroxyethyl starch offers no benefits over saline for fluid resuscitation in critically ill patients and may have renal consequences, shows a randomized trial.

23 Oct 2012

Leg press power best indicator of function after knee arthroplasty

Leg press power is a better indicator of performance-based and self-reported functionality after total knee arthroplasty than knee extension strength, show study findings.

23 Oct 2012

Metabolic pathway for insulin effects of sleep identified

Sleep deprivation reduces insulin sensitivity in human fat cells, which could, over time, lead to metabolic disorders such as diabetes, researchers report.

23 Oct 2012

Almost all children on intensive care units given ‘off-label’ drugs

Study results show that a very high proportion of children admitted to intensive care units are treated with “off-label” drugs that have not been tested for the specific age or condition of the patient.

23 Oct 2012

Antipsychotic drug quandary for Alzheimer’s patients

Stopping treatment with risperidone to limit side effects risks the return of psychosis or agitation in patients with Alzheimer’s disease who have been taking the drug to suppress such symptoms, research shows.

23 Oct 2012

Initial insight into sedentary behavior counseling practices in primary care settings

Although primary care physicians take care of many aspects of health and disease, little is known about how they can change sedentary behavior through counseling, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

23 Oct 2012

Study still implicates amyloid beta in causing Alzheimer's dementia

Researchers at Washington University School of Medicine in St. Louis have found a key difference in the brains of people with Alzheimer's disease and those who are cognitively normal but still have brain plaques that characterize this type of dementia.

23 Oct 2012

SUNY Downstate to participate in Urban Universities for HEALTH

SUNY Downstate Medical Center has been selected as one of five institutions to participate in Urban Universities for HEALTH (Health Equity through Alignment, Leadership, and Transformation of the Healthcare Workforce), a national initiative that aims to improve the health of urban communities by developing their health workforce.

23 Oct 2012

SLU medical students to raise awareness about teen suicide among tech savvy millennials

Two Saint Louis University medical students are taking the multimedia route to raise awareness about teen suicide among tech savvy millennials.

23 Oct 2012

Genzyme, Alnylam partner to develop and commercialize RNAi therapeutics against ATTR

Alnylam Pharmaceuticals, Inc. and Genzyme, a Sanofi company, announced today that they have formed an exclusive alliance to develop and commercialize RNAi therapeutics targeting transthyretin (TTR) for the treatment of transthyretin-mediated amyloidosis (ATTR) in Japan and other Asia-Pacific countries.

23 Oct 2012

Austrian researchers receive $7.4 million award to verify new breast cancer pathways

The innovator's award recognises Josef Penninger's work in identifying a key molecular pathway how hormone replacement therapies and contraceptive pills can lead to breast cancer. His team provided the first genetic proof that a protein called RANKL is the master regulator of bone loss, which has contributed to the development of a novel drug already approved for the treatment of osteoporosis and skeletal related events in multiple cancers.

23 Oct 2012

Researchers discover how HIV-infected people develop very powerful antibody responses

Wits researchers have played a pivotal role in an AIDS study published today in the journal, Nature Medicine, which describes how a unique change in the outer covering of the virus found in two HIV infected South African women enabled them to make potent antibodies which are able to kill up to 88% of HIV types from around the world.

23 Oct 2012

First Edition: October 23, 2012

Today's headlines include various reports from the campaign trail as well as the latest news about current meningitis outbreak.

23 Oct 2012

Possible overlap exists between inflammatory bowel disease and IBS

Research unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas suggests a possible overlap of symptoms of two prevalent GI disorders: irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) and further suggests a possible link between subtle GI tract inflammation and IBS symptoms-a link that is also the focus of the first systemic review of the literature on this topic and an editorial both published in this month's American Journal of Gastroenterology.

23 Oct 2012

Patients with Type 2 Diabetes may face increased risk of Barrett's Esophagus

Patients with Type 2 Diabetes may face an increased risk for Barrett's Esophagus (BE), regardless of other risk factors including smoking, alcohol consumption, obesity and gastroesophageal reflux disease (GERD), according to research unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

23 Oct 2012