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How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

Genetic variants associated with adult obesity start playing a role during early childhood

Body mass index in infants, children and adults is influenced by different genetic factors that change as we age, according to a major new study.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

Researchers map uncharted area of genome using advanced imaging

Using advanced imaging techniques, researchers at the University of Colorado Anschutz Medical Campus have mapped a previously uncharted region of the human genome that gives rise to a variety of disease, setting the stage to potentially test for the conditions in the future.

4 Sep 2019

A factor that predicts prolonged survival in brain tumor uncovered

The discoveries in the cellular and molecular biology of cancer, the development of drugs against specific genetic mutations, and the emergence of immunotherapy are allowing the cure or improvement of the quality of life and life expectancy of patients with tumors.

3 Sep 2019

CRISPR-Cas9 successfully reverses type 2 diabetes in mice

Researchers have used CRISPR-Cas9 to treat obesity and type 2 diabetes in mice, a development that could eventually benefit humans.

3 Sep 2019

SATI gene editing could replace CRISPR

Scientists have developed a new gene editing tool called SATI that is safer than CRISPR.

2 Sep 2019

DNA methylation closely linked to telomere length

Aging is associated with multiple disease conditions. Recently it has been found that many of these illnesses are linked to the length of the telomeres at the ends of every chromosome. Telomere length (TL) is affected by both genetic and epigenetic contributions.

2 Sep 2019

Understanding yeast with probiotic properties

Researchers led by Prof. Johan Thevelein (VIB-KU Leuven Center for Microbiology) have discovered that Saccharomycesboulardii, a yeast with probiotic properties, produces uniquely excessive amounts of acetic acid, the main component of vinegar.

30 Aug 2019

Cell-free DNA identifies pathogens and quantifies injuries to organs

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression.

29 Aug 2019

A detailed map to understand how viruses infect human cells

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect.

29 Aug 2019

The Kavli Foundation gifts $3 million to support neuroscience research at Salk

The Salk Institute announced today that The Kavli Foundation has committed $3 million to support ongoing neuroscience research at Salk as part of the joint UCSD-Salk Kavli Institute for Brain and Mind.

29 Aug 2019

New model system uses red blood cells to study malaria invasion

Researchers at the University of Bristol and Imperial College London have established a new model system that uses red blood cells grown in the laboratory to study how malaria parasites invade red blood cells.

29 Aug 2019

Parasites could have originated from transmissable cancers

Researchers have presented a controversial new theory suggesting that transmissible cancers could eventually evolve into their own multicellular species.

29 Aug 2019

[BC]2 conference focuses on use of big data in molecular medicine

From 9 to 11 September, the [BC]2 Basel Computational Biology Conference, organized by the SIB Swiss Institute of Bioinformatics, will bring together international and Swiss-based scientists working in this field, in one of the key bioinformatics events in Europe: a prime opportunity to hear from leading experts, from precision oncology to infectious diseases.

29 Aug 2019

UC San Francisco scientists identify second 'short sleep' gene after 10-year search

After a decade of searching, the UC San Francisco scientists who identified the only human gene known to promote "natural short sleep" -- lifelong, nightly sleep that lasts just four to six hours yet leaves individuals feeling fully rested -- have discovered a second.

28 Aug 2019

Researchers find a weak spot in cancer cells

Cancer cells form tumors. This statement, simple as it seems, hides a complex failure of normal immune responses that should eliminate tumor cells from the body before they ever form viable cancer masses.

28 Aug 2019

U of T scientists create antibodies with enormous potential for regenerative medicine

Our body makes antibodies to fight infections. But the synthetic versions of these molecules could hold the key to stimulating the body's ability to regenerate.

27 Aug 2019

Researchers develop simple method for isolating placental cells from cervical swabs

Brown University researchers have developed a simple method for isolating placental cells from cervical swabs. The technique, described in the journal Scientific Reports, could aid in developing less invasive ways of diagnosing genetic disorders in developing fetuses.

27 Aug 2019