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Antibiotics may be the new weapon to fight against melanoma

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental Medicine.

22 Jul 2021

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

22 Jul 2021

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published.

22 Jul 2021

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

Some of these variants, known as variants of concern (VoC), have a much higher rate of transmission and increased mortality than the original SARS-CoV-2 strain. Therefore, it is imperative to assess the efficacy of the available vaccines against the circulating SARS-CoV-2 strains. In addition, tracking the continuously evolving genetic variants is also vital to prevent future outbreaks.

22 Jul 2021

New method predicts if COVID-19 clinical trials will be completed or suspended

In order to win the battle against COVID-19, studies to develop vaccines, drugs, devices and re-purposed drugs are urgently needed.

21 Jul 2021

Researchers propose new scoring system for assessing wound healing dynamics

Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time.

21 Jul 2021

New project aims to reduce smokeless tobacco use in American Indian communities

The College of Health Institute for Indigenous Studies has been awarded nearly $1.8 million from the American Cancer Society. The project will test the efficacy of a culturally tailored program aimed at reducing American Indian smokeless tobacco use.

21 Jul 2021

Scientists identify gut microbiota dysbiosis as a potential risk factor for long COVID

A study in Norway has recently highlighted a significant association between gut microbiota alteration and persistent respiratory dysfunction in coronavirus disease 2019 (COVID-19) patients.

21 Jul 2021

How to run a COVID-19 vaccination campaign: lessons from other infectious outbreaks

A new paper, available on the medRxiv* preprint server, presents lessons learned from the implementation of three adult vaccine programs in low- and middle-income countries (LMICs) in Africa and South America.

21 Jul 2021

COVIDcast API: An open repository of real-time COVID-19 indicators

A new preprint available on the medRxiv* server reports the utility of the COVIDcast API, a database of all COVID-19 indicators that are constantly being updated, dating from April 2020.

21 Jul 2021

Analysis: Necessary or not, covid booster shots are probably on the horizon

The drugmaker Pfizer recently announced that vaccinated people are likely to need a booster shot to be effectively protected against new variants of covid-19 and that the company would apply for Food and Drug Administration emergency use authorization for the shot.

21 Jul 2021

Potent nasal vaccine protects non-human primates from SARS-CoV-2

A team of US-based scientists has recently demonstrated the efficacy of a live attenuated, recombinant coronavirus disease 2019 (COVID-19) vaccine candidate currently under phase I clinical trial as a single-dose intranasal vaccine.

20 Jul 2021

Structural changes in receptor-binding interface may induce immune fitness of SARS-CoV-2 delta variant

Florida International University researchers have investigated the mutation-induced structural changes in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could contribute to its immune evasion abilities.

20 Jul 2021

Study shows promise of combining radiation therapy with dendritic-cell vaccines for breast cancer

A research team led by Fumito Ito, MD, PhD, FACS, of Roswell Park Comprehensive Cancer Center reports new data on the promise of combining standard treatment for breast cancer with a particular form of cancer immmunotherapy - dendritic-cell (DC) treatment vaccines.

20 Jul 2021

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

Researchers in Canada have developed an adenoviral vector-based vaccine against coronavirus disease 2019 (COVID-19) that induced robust immune protection against the ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.

20 Jul 2021

CEPI and IVI announce new research program to expand access to COVID-19 vaccines in Africa

The Coalition for Epidemic Preparedness Innovations and the International Vaccine Institute today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in Africa.

20 Jul 2021

Study examines clinical outcomes in vaccinated individuals hospitalized with SARS-CoV-2 Delta variant

A new study has been published on the medRxiv* preprint server that has evaluated the clinical outcomes of the COVID-19 patients hospitalized in AIG hospitals, Hyderabad, India, between April 24, 2021, and May 31, 2021.

20 Jul 2021

Study reports on COVID-19 vaccine uptake and antibody prevalence in England during May 2021

A new study reports this finding, along with varying antibody prevalence among different groups and regions and between different age groups. In the current paper, available as a preprint on the medRxiv* server, the results of the sixth round of the REACT-2 study are reported.

20 Jul 2021

COVID-19 vaccination in New York City reduces hospital admissions and deaths

A new study, released as a preprint on the medRxiv* server, shows how the successful rollout of effective COVID-19 vaccines in this metropolis led to the dramatic reduction in the number of cases with moderate to severe coronavirus disease 2019 (COVID-19) and curbed COVID-19-related mortality.

20 Jul 2021

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

The ongoing coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 190 million cases worldwide. Of these, over 4 million have died due to the infection.

20 Jul 2021

Efficacy News and Research

Antibiotics may be the new weapon to fight against melanoma

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

New method predicts if COVID-19 clinical trials will be completed or suspended

Researchers propose new scoring system for assessing wound healing dynamics

New project aims to reduce smokeless tobacco use in American Indian communities

Scientists identify gut microbiota dysbiosis as a potential risk factor for long COVID

How to run a COVID-19 vaccination campaign: lessons from other infectious outbreaks

COVIDcast API: An open repository of real-time COVID-19 indicators

Analysis: Necessary or not, covid booster shots are probably on the horizon

Potent nasal vaccine protects non-human primates from SARS-CoV-2

Structural changes in receptor-binding interface may induce immune fitness of SARS-CoV-2 delta variant

Study shows promise of combining radiation therapy with dendritic-cell vaccines for breast cancer

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

CEPI and IVI announce new research program to expand access to COVID-19 vaccines in Africa

Study examines clinical outcomes in vaccinated individuals hospitalized with SARS-CoV-2 Delta variant

Study reports on COVID-19 vaccine uptake and antibody prevalence in England during May 2021

COVID-19 vaccination in New York City reduces hospital admissions and deaths

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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