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New insights into how red meat-rich diet increases cardiovascular disease risk

A Cleveland Clinic-led study has revealed new insights into how a diet rich in red meat increases risk for cardiovascular disease. The findings were published in Nature Microbiology and build on more than a decade of research by lead author Stanley Hazen, MD, PhD.

23 Dec 2021

Impact of the rapid spread of the SARS-CoV-2 Omicron variant in Southern Africa

A new study has focused on the genomic profile and early transmission dynamics of Omicron. This study revealed the dominance of the Omicron variant in regions with high levels of population immunity.

23 Dec 2021

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.

23 Dec 2021

New study shines light on how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

22 Dec 2021

Newly discovered species of Enterococcus bacteria named after the John Innes Centre

A newly discovered species of antibiotic-resistant bacteria has been named after the academic institute where it was identified – the John Innes Centre.

22 Dec 2021

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute lymphoblastic leukemia, a new study shows.

22 Dec 2021

Researchers identify novel cancer markers in patients with aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

22 Dec 2021

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the nucleus, which is necessary for the production of new viruses.

22 Dec 2021

Researchers use network modeling to hone in on cancer gene interactions critical to malignancy

Wilmot Cancer Institute researchers are a step closer to understanding the complex gene interactions that cause a cell to become malignant.

21 Dec 2021

Deletion of autism-linked gene diminishes myelin in mice

Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, new research finds.

21 Dec 2021

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Interesting research decrypts a recurring sequence in antibodies against severe acute respiratory syndrome 2 (SARS-CoV-2) and identifies it to be a board neutralizing antibody that targets a conserved epitope on the SARS-CoV-2 receptor-binding domain (RBD) of the spike protein.

21 Dec 2021

Pandemic poses short- and long-term risks to babies, especially boys

The pandemic has created a hostile environment for pregnant people and their babies. Stress levels among expectant mothers have soared. Pregnant women with covid are five times as likely as uninfected pregnant people to require intensive care and 22 times as likely to die. Infected moms are four times as likely to have a stillborn child.

21 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

Researchers use machine learning to shed light on genetic mutations linked with spina bifida

Weill Cornell Medicine researchers are using machine learning, a form of artificial intelligence, to shed light on genetic mutations associated with spina bifida.

20 Dec 2021

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Researchers conduct a comprehensive in vitro analysis of relatively unexplored host immune responses during SARS-CoV-2 infection.

20 Dec 2021

Study identifies genetic causes of sudden unexplained deaths in children aged 1 year and older

A new study found that changes in specific genes may contribute each year to the roughly 400 sudden unexplained deaths in children (SUDC) aged 1 year and older—and separately from sudden infant death syndrome (SIDS).

20 Dec 2021

Study reveals chromosome-level changes that relate to drug resistance in melanoma

Precision therapies targeting melanoma and other cancers have improved patient survival, but tumors often stop responding to drugs, and recent studies point to changes in DNA – both inside and outside chromosomes – as a driving factor in tumor genesis as well as in treatment resistance.

20 Dec 2021

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

Genes News and Research

New insights into how red meat-rich diet increases cardiovascular disease risk

Impact of the rapid spread of the SARS-CoV-2 Omicron variant in Southern Africa

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

New study shines light on how brain cells die in prion diseases

Newly discovered species of Enterococcus bacteria named after the John Innes Centre

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

Researchers identify novel cancer markers in patients with aggressive prostate cancer

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

Researchers use network modeling to hone in on cancer gene interactions critical to malignancy

Deletion of autism-linked gene diminishes myelin in mice

Promising new drug target for TB identified

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Pandemic poses short- and long-term risks to babies, especially boys

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

Researchers use machine learning to shed light on genetic mutations linked with spina bifida

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Study identifies genetic causes of sudden unexplained deaths in children aged 1 year and older

Study reveals chromosome-level changes that relate to drug resistance in melanoma

Impact of acute kidney injury associated gene expression in human kidney cells

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