Genomic News and Research

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New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF.

28 Jun 2010

Researchers identify a key player in dramatic loss of neurons in mice and fly models

A team of researchers, led by scientists at the University of California, San Diego, have identified a key player in the dramatic loss of neurons in mice and fly models, a discovery that could help illuminate the role of mitochondrial dysfunction in human neurodegenerative disorders, such as Parkinson's disease.

25 Jun 2010

Researchers develop experimental approaches, analysis tools to understand phenotypic expression

The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace.

23 Jun 2010

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

OvaGene Oncology Inc., a biotechnology company specializing in the development and commercialization of personalized DNA-based diagnostics for gynecologic cancer, announced today the opening of its new clinical and research laboratory in Irvine, California. This state-of-the-art facility will serve as the central headquarters for operations, research, and molecular clinical lab testing.

23 Jun 2010

Michigan State University researchers analyze histiocytic sarcomas

Michigan State University veterinarians are taking part in a two-year, $5.3 million project to analyze five cancers in dogs, research that could offer new insight into canine cancer genes and their potential impact on the human form of the disease.

22 Jun 2010

Life Technologies announces product launches in concert with ISSCR 8th Annual Meeting

Life Technologies Corporation, a provider of innovative life science solutions, today announced activities and product launches in concert with the International Society for Stem Cell Research (ISSCR) 8th Annual Meeting that highlight the company's offerings of complete end-to-end solutions for stem cell research. Stem cell research has been shown to be a critical component of regenerative medicine; a basis for identifying drug targets and drug screening; and an important step in the development of therapies to treat a variety of diseases.

18 Jun 2010

An ubiquitin-specific peptidase that potentially promote cancer cell necrosis

"ubiquitin-specific peptidase 21 (USP21) has been identified as another essential player in regulation of tumor necrosis factor alpha (TNF-alpha)-induced nuclear factor kappaB (NF-kappaB) activation by working on receptor-interacting protein 1(RIP1)."

18 Jun 2010

Gen-Probe invests $50M in Pacific Biosciences

Gen-Probe Incorporated and Pacific Biosciences announced today that Gen-Probe has made a $50 million strategic investment in Pacific Biosciences, a private sequencing company. In addition, the companies will work together to explore co-development of new integrated clinical diagnostics systems based on Pacific Biosciences' Single Molecule Real Time (SMRT™) platform and Gen-Probe's expertise in diagnostics.

18 Jun 2010

NuGEN Technologies receives State of California cGMP certification

NuGEN Technologies, the provider of innovative RNA and DNA amplification and sample preparation technologies for breakthrough genomic analysis, today announced it has received the State of California cGMP (current Good Manufacturing Practices) certification following a rigorous audit process. NuGEN is one of the first sample preparation companies to receive this certification, which allows the company to manufacture and ship any of its products under cGMP compliance.

17 Jun 2010

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

The Institute for Systems Biology (ISB) of Seattle, WA, is collaborating with the Gladstone Institute of Neurological Disease (GIND) and its Taube-Koret Center for Huntington's Disease Research to use whole-genome sequencing to identify genes and novel drug targets related to the onset and progression of Huntington's disease (HD). The research team, led by GIND associate director and senior investigator Steven Finkbeiner, MD, PhD, will also use induced pluripotent stem (iPS) cells from patients with HD to screen for drugs that might delay, prevent, or even reverse this devastating condition.

16 Jun 2010

SQNM first-quarter 2010 total revenues up 22%: MicroStockProfit.com

MicroStockProfit.com announces an investment report featuring Sequenom Inc. The report includes financial, comparative and investment analyses, and industry information you need to know to make an educated investment decision.

15 Jun 2010

NuGEN launches Encore NGS Library/Multiplex Systems and Ovation 3'-DGE System

NuGEN®, the provider of innovative RNA and DNA amplification and sample preparation technologies for breakthrough genomic analysis, today announced the introduction of its Encore NGS Library/Multiplex Systems and the Ovation 3'-DGE System. Together with the Ovation RNA-Seq System, launched in 2009, NuGEN is continuing to provide life sciences researchers with innovative and versatile sample preparation reagents that enable a broad range of Next Generation Sequencing (NGS) applications through fast, simple and scalable workflows.

11 Jun 2010

New methodology may help control influenza

Scientists have uncovered the flu's secret formula for effectively evolving within and between host species: balance. The key lies with the flu's unique replication process, which has evolved to produce enough mutations for the virus to spread and adapt to its host environment, but not so many that unwanted genomic mutations lead to the flu's demise (catastrophic mutagenesis).

11 Jun 2010

NanoString Technologies launches new solution to detect CNVs in human genomic samples

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the launch of its early access program for a unique new solution that detects copy number variation in human genomic samples. The program was announced in conjunction with the company's participation in the European Human Genetics Conference in Gothenburg, Sweden.

From NanoString Technologies 10 Jun 2010

Baylor Institute of Immunology Research receives nearly $35M as grants in 2009

Even in an economy that's proved devastating to charitable giving and government grants, the Baylor Institute of Immunology Research (BIIR), a component of Baylor Research Institute (BRI), has managed to buck the trend: BIIR received grants totaling nearly $35 million in 2009.

10 Jun 2010

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

New techniques to detect chromosomal abnormalities can offer a higher degree of accuracy. Chromosomal abnormalities are a well-known cause of multiple congenital anomalies, and conventional methods of culture analysis have proven unsuccessful in 10% to 40% of cases. Comparative genomic hybridization (CGH) and fluorescent in situ hybridization (FISH) techniques were tested and found successful by analyzing tissue from children who had multiple congenital anomalies.

9 Jun 2010

Takara Bio to distribute NuGEN's solutions in Japan, South Korea, China

NuGEN, the provider of innovative RNA and DNA sample preparation technologies that enable breakthrough genomic analysis, today announced it has signed a non-exclusive agreement with Takara Bio to distribute the full spectrum of NuGEN's next-generation sequencing, microarray and q-PCR nucleic acid amplification and sample preparation products in Japan, South Korea and China. In addition, Takara is authorized to offer services using NuGEN products in the same territory.

9 Jun 2010

Fluidigm develops world's first reusable bio-chip architecture

Fluidigm Corporation today announced it has developed the world's first reusable bio-chip architecture for the commercial market. These reusable integrated fluidic circuits (IFCs) will dramatically lower SNP genotyping costs and are designed to support accelerated sample throughput, while maintaining data quality of 99.75 percent or greater accuracy and 99 percent or greater call rates.

9 Jun 2010

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor. The research focused on a new way to attack the tumors by blocking the Hedgehog pathway that is linked to approximately 20 percent of medulloblastomas.

8 Jun 2010

Quintiles announces comprehensive suite of PI3K biomarker assays

Quintiles today announced a comprehensive suite of biomarker assays to help biopharmaceutical companies investigate the phosphoinositide 3-kinases (PI3K) cancer survival pathway, the focus of numerous anti-cancer therapies under development. Understanding the PI3K pathway is essential in developing new medicines to inhibit or block this pathway, thereby cutting off a metabolic function needed for certain cancers to survive.

8 Jun 2010

Genomic News and Research

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

Researchers identify a key player in dramatic loss of neurons in mice and fly models

Researchers develop experimental approaches, analysis tools to understand phenotypic expression

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

Michigan State University researchers analyze histiocytic sarcomas

Life Technologies announces product launches in concert with ISSCR 8th Annual Meeting

An ubiquitin-specific peptidase that potentially promote cancer cell necrosis

Gen-Probe invests $50M in Pacific Biosciences

NuGEN Technologies receives State of California cGMP certification

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

SQNM first-quarter 2010 total revenues up 22%: MicroStockProfit.com

NuGEN launches Encore NGS Library/Multiplex Systems and Ovation 3'-DGE System

New methodology may help control influenza

NanoString Technologies launches new solution to detect CNVs in human genomic samples

Baylor Institute of Immunology Research receives nearly $35M as grants in 2009

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

Takara Bio to distribute NuGEN's solutions in Japan, South Korea, China

Fluidigm develops world's first reusable bio-chip architecture

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Quintiles announces comprehensive suite of PI3K biomarker assays

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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