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New strategies to prevent ventilator-associated pneumonia in critically ill children

Implementation of a bundle for prevention of ventilator-associated pneumonia in critically ill infants and children may lead to lower rates of VAP in these patients, according to an article in the June issue of Critical Care Nurse.

4 Jun 2013

Ophthalmologists warn that overexposure to sun's UV rays can cause temporary blindness

With the arrival of summer, when the sun's ultraviolet rays are strongest, ophthalmologists − medical doctors who specialize in the diagnosis, medical and surgical treatment of eye diseases and conditions − are warning the public that overexposure to these rays can burn the eyes' corneas and cause painful, temporary blindness.

4 Jun 2013

People with type 2 diabetics, hypertension more likely to have obstructive sleep apnea: Study

The American Academy of Sleep Medicine is advising anyone with Type 2 diabetes or hypertension to be evaluated for sleep apnea by a board-certified sleep medicine physician. The recommendation comes as the group of international clinicians and researchers meets in Baltimore for SLEEP 2013, the foremost gathering of sleep experts annually.

4 Jun 2013

Soligenix receives FDA Fast Track designation for SGX942 to treat patients with oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company, announced today that its SGX942 development program for the treatment of oral mucositis as a result of radiation and/or chemotherapy treatment in head and neck cancer patients has received "Fast Track" designation from the US Food and Drug Administration.

3 Jun 2013

Amgen reports encouraging results from talimogene laherparepvec phase 3 study in patients with metastatic melanoma

Amgen today announced detailed results from a pivotal Phase 3 trial evaluating talimogene laherparepvec in patients with unresected stage IIIB, IIIC or IV melanoma compared to granulocyte-macrophage colony-stimulating factor (GM-CSF).

3 Jun 2013

NanoString's Prosigna Breast Cancer Assay can help identify node-positive early-stage breast cancer

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced new results from the combined data analysis of the Austrian Breast & Colorectal Cancer Study Group 8 (ABCSG-8) and Arimidex, Tamoxifen, Alone or in Combination studies.

From NanoString Technologies 3 Jun 2013

Lung cancer patients are likely to fare better if treated with targeted therapy than with chemotherapy

Thousands of patients with an advanced form of lung cancer that carries a specific dysfunctional gene are likely to fare better if treated with a targeted therapy than with traditional chemotherapy, report Dana-Farber Cancer Institute researchers and a team of international collaborators.

3 Jun 2013

Human tumors with MET amplification respond to MET inhibitor drugs

A subset of colorectal cancers responds to anti-epidermal growth factor receptor (anti-EGFR) therapies, but develops resistance within months. Among cancers that develop resistance to anti-EGFR therapy, some showed overexpression of a gene called MET, according to a study published in the June issue of Cancer Discovery, a journal of the American Association for Cancer Research.

3 Jun 2013

Study finds HER2 irregularities in 14 different advanced solid tumors

The HER2 growth-factor gene is known to be over-active in breast and gastro-esophageal cancers. But now, irregularities in the genes's expression - among them mutations, amplifications, substitutions, and translocations - have been found in 14 different advanced solid tumors.

3 Jun 2013

Sorafenib stops tumor growth, provides effective treatment for thyroid cancer patients

The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which will be presented today by a researcher from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania in a plenary session during the American Society of Clinical Oncology's annual meeting.

3 Jun 2013

Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Spouses and long-term partners of patients with mouth and throat cancers related to infection with the human papilloma virus (HPV) appear to have no increased prevalence of oral HPV infections, according to results of a multicenter, pilot study led by Johns Hopkins investigators.

3 Jun 2013

Mount Sinai researchers present landmark studies at ASCO meeting

Icahn School of Medicine at Mount Sinai researchers will present several landmark studies at the 2013 American Society of Clinical Oncology meeting May 31-June 4, 2013 in Chicago, including data on the likelihood of spousal human papillomavirus oral infection, new gene signatures in melanoma, and issues with high readmission rates after cancer surgery.

3 Jun 2013

Saint Louis University extends search for new medicines to treat childhood diarrhea

A $750,000 grant to the Center for World Health and Medicine at Saint Louis University will extend the search for new medicines to treat childhood diarrhea, which is the second leading cause of death of young children worldwide.

1 Jun 2013

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced that a clinical study of the Prosigna Breast Cancer Assay will be presented during the Breast Cancer Oral Abstract Session at the 2013 Annual American Society of Clinical Oncology Meeting on Sunday, June 2.

From NanoString Technologies 1 Jun 2013

New drug for multiple myeloma could be available within next few months in Europe

The International Myeloma Foundation - improving the quality of life of myeloma patients while working toward prevention and a cure - today said the newest drug for treating multiple myeloma could be available to patients in Europe within the next few months.

1 Jun 2013

Research roundup: Questioning money-saving value of kids' preventive dentistry, weight loss

Although early preventive dental visits are widely recommended for children, it is unclear whether they reduce future dental visits or costs.

1 Jun 2013

Depomed receives complete response letter for SEFELSA NDA

Depomed, Inc., a specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration issued a complete response letter to the New Drug Application for SEFELSA, Depomed's investigational, oral, twice daily formulation of gabapentin to treat moderate to severe vasomotor symptoms due to menopause.

1 Jun 2013

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

A new study conducted in an ethnically diverse and predominantly low income population found that only one-fifth of rheumatoid arthritis patients had an overall adherence rate to prescribed oral medications at 80% or greater.

1 Jun 2013

Alios begins oral dosing of ALS-8176 in Phase 1 clinical trial for RSV infection

Alios BioPharma, Inc. today announced that it has begun oral dosing of ALS-8176 in a Phase 1 clinical trial. ALS-8176 is a structurally novel, anti-respiratory syncytial virus (RSV) nucleoside analog that is being developed for the treatment of acute RSV infection.

31 May 2013

New research shows uremic toxins increase heart attack risk

MD-Patients with advanced kidney disease who are undergoing hemodialysis are known to be highly susceptible to heart attacks and other cardiovascular complications, and now scientists likely know why.

31 May 2013

Oral News and Research

New strategies to prevent ventilator-associated pneumonia in critically ill children

Ophthalmologists warn that overexposure to sun's UV rays can cause temporary blindness

People with type 2 diabetics, hypertension more likely to have obstructive sleep apnea: Study

Soligenix receives FDA Fast Track designation for SGX942 to treat patients with oral mucositis

Amgen reports encouraging results from talimogene laherparepvec phase 3 study in patients with metastatic melanoma

NanoString's Prosigna Breast Cancer Assay can help identify node-positive early-stage breast cancer

Lung cancer patients are likely to fare better if treated with targeted therapy than with chemotherapy

Human tumors with MET amplification respond to MET inhibitor drugs

Study finds HER2 irregularities in 14 different advanced solid tumors

Sorafenib stops tumor growth, provides effective treatment for thyroid cancer patients

Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Mount Sinai researchers present landmark studies at ASCO meeting

Saint Louis University extends search for new medicines to treat childhood diarrhea

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

New drug for multiple myeloma could be available within next few months in Europe

Research roundup: Questioning money-saving value of kids' preventive dentistry, weight loss

Depomed receives complete response letter for SEFELSA NDA

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

Alios begins oral dosing of ALS-8176 in Phase 1 clinical trial for RSV infection

New research shows uremic toxins increase heart attack risk

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