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International scientists identify novel genetic defects that induce oesophageal cancer

A team of scientists from the Cancer Science Institute of Singapore at the National University of Singapore and National University Cancer Institute Singapore, and their collaborators from the Cedars-Sinai Medical Centre, UCLA School of Medicine, demonstrated that a number of novel genetic defects are able to induce oesophageal cancer.

31 Mar 2014

New high-risk cancer causing mutation identified for melanoma development

Researchers have discovered that mutations in a specific gene are responsible for a hereditary form of melanoma.

31 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

The National Cancer Institute has awarded a three-year grant totaling $2,168,535 to Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine, for his research into the role of noncoding RNAs in cancer and other diseases.

28 Mar 2014

Personalis and Inova team up to advance genomic medicine

Inova Translational Medicine Institute and Personalis, Inc. today announced a partnership to advance genomic medicine for Inova's patient population.

27 Mar 2014

Researchers to discuss implications of genomic sequencing at ACMG meeting

Researchers from the Mayo Clinic Center for Individualized Medicine will present results of three different studies evaluating implications and feasibility of genome sequencing at the ACMG Annual Clinical Genetics Meeting this week in Nashville, Tenn.

27 Mar 2014

A fast, non-invasive method to genotype late-onset Alzheimer's disease

The apolipoprotein E gene ε4 allele is considered a negative factor for neural regeneration in late-onset Alzheimer's disease cases.

27 Mar 2014

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.

25 Mar 2014

Not all doctors offer cancer gene testing to patients, study finds

Many cancer researchers believe that cutting-edge advances in genomics will pave the way for personalized or "precision" cancer medicine for all patients in the near future. A new study by researchers at Dana-Farber Cancer Institute, however, suggest that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients.

25 Mar 2014

NSCLC gene fusion testing, targeted crizotinib – not yet cost effective

Genomic fusion testing for echinoderm microtubule-associated protein-like 4 and anaplastic lymphoma kinase genes plus targeted first-line crizotinib is not a cost effective treatment strategy for patients with advanced non-squamous non-small-cell lung cancer, shows a Canadian analysis.

20 Mar 2014

Genomic analysis to study cancer in dogs can help develop new therapies for human cancers

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof-of-concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

19 Mar 2014

USTAR Center for Genetic Discovery to integrate genome data with patient care

The USTAR Center for Genetic Discovery is partnering with California based Omicia, Inc, to make analyzing a patient's genome as routine as performing a blood test.

19 Mar 2014

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

So many variables can contribute to shortness of breath that no person can keep them all straight. But a computer program, capable of tracking more than 100 clinical variables for almost 400 people, has shown it can identify various subtypes of asthma, which perhaps could lead to targeted, more effective treatments.

19 Mar 2014

Trovagene reports net loss of $1 million for fourth quarter 2013

Trovagene, Inc., a developer of cell-free molecular diagnostics, today reported its financial results for the quarter and the year ended December 31, 2013.

18 Mar 2014

TAF proteins may serve as potential targets to fight ovarian cancer

In the complex genomic and molecular conspiracy that gives rise to ovarian cancer, what if researchers have been missing a whole set of suspects because they've been hiding in plain sight?

17 Mar 2014

Biomedical scientist to receive Chen Award for distinguished achievement in genetic and genomic research

The international Human Genome Organization (HUGO) will present its top award to Jackson Laboratory President and CEO Edison Liu, M.D.

17 Mar 2014

Study suggests effective therapeutics for IBD may hinge on targeting GM-CSF axis

The protein GM-CSF plays a critical role in maintaining immune tolerance in the gut, with defects in the protein increasing the susceptibility to inflammatory bowel diseases (IBD), according to a new mouse study by a team of researchers from the Icahn School of Medicine at Mount Sinai.

17 Mar 2014

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

13 Mar 2014

Teen researcher wins top award from Intel Foundation for research on potential drugs to treat influenza

From new cancer treatments to an exploration of how technology affects the adolescent brain, the innovative research of America's future scientists, engineers and inventors took center stage in the nation's capital today.

12 Mar 2014

MIT biologists discover how cancer cells make their escape

About 90 percent of cancer deaths are caused by tumors that have spread from their original locations. This process, known as metastasis, requires cancer cells to break loose from their neighbors and from the supportive scaffold that gives tissues their structure.

11 Mar 2014

Genomic News and Research

International scientists identify novel genetic defects that induce oesophageal cancer

New high-risk cancer causing mutation identified for melanoma development

Discovery could lead to new medications for cancer, say Rice University scientists

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

Personalis and Inova team up to advance genomic medicine

Researchers to discuss implications of genomic sequencing at ACMG meeting

A fast, non-invasive method to genotype late-onset Alzheimer's disease

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Not all doctors offer cancer gene testing to patients, study finds

NSCLC gene fusion testing, targeted crizotinib – not yet cost effective

Genomic analysis to study cancer in dogs can help develop new therapies for human cancers

USTAR Center for Genetic Discovery to integrate genome data with patient care

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

Trovagene reports net loss of $1 million for fourth quarter 2013

TAF proteins may serve as potential targets to fight ovarian cancer

Biomedical scientist to receive Chen Award for distinguished achievement in genetic and genomic research

Study suggests effective therapeutics for IBD may hinge on targeting GM-CSF axis

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

Teen researcher wins top award from Intel Foundation for research on potential drugs to treat influenza

MIT biologists discover how cancer cells make their escape

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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