Protein C News and Research

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The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Researchers compared the effects of an experimental low-carbohydrate and high-protein diet and orlistat with that of a control diet to examine their impact on Asian MAFLD patients with obesity.

14 Feb 2023

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition.

14 Feb 2023

Do nuts help with type 2 diabetes?

Type 2 diabetes is a metabolic disorder that affects one in ten people worldwide. There has been an alarming increase of 16% in the global prevalence of type 2 diabetes over the past two years.

13 Feb 2023

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

A study reveals a previously unknown way in which cannabidiol (CBD), a substance found in cannabis, reduces seizures in many treatment-resistant forms of pediatric epilepsy.

13 Feb 2023

Similar autoantibody profiles in long COVID and fully recovered individuals

Researchers evaluate autoreactive antibody profiles after SARS-CoV-2 infection.

13 Feb 2023

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils.

13 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes.

13 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

MicroRNAs associated with diabetes in human pancreatic islets

In a recent study published in the Proceedings of the National Academy of Sciences, researchers explored micro-ribonucleic acids (RNAs) associated with diabetes and related characteristics in human pancreatic islets.

13 Feb 2023

Could trained scent-detection dogs be used for chronic wasting disease surveillance?

A recent study published in Prion investigated whether trained scent-detection dogs could be used for chronic wasting disease (CWD) surveillance.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Bivalent booster recipients show slightly higher protection against infection and significantly higher protection against death than monovalent booster recipients

Researchers reported the immune protection conferred by monovalent COVID-19 vaccines and bivalent booster doses.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Plasma D-dimer measurement can provide useful information when diagnosing periprosthetic joint infection

Measurement of plasma D-dimer levels – a test more commonly used to detect blood-clotting disorders – can provide useful information when making the difficult diagnosis of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery.

10 Feb 2023

Smoking tobacco and vaping e-cigarettes may increase healthy young people's risk for severe COVID

New UCLA research suggests that smoking tobacco and vaping electronic cigarettes may increase healthy young people's risk for developing severe COVID illness.

10 Feb 2023

Molecular switch regulates autophagy in plants

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon persistent cellular stress.

10 Feb 2023

Review strengthens evidence that repetitive head impact exposure as chief risk factor for CTE

During the past 17 years, there has been a remarkable increase in scientific research concerning chronic traumatic encephalopathy (CTE) with researchers at the BU CTE Center at the forefront.

10 Feb 2023

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS—short for peptidyl-tRNA enrichment using organic extraction and silica adsorption.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Protein C News and Research

The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

Do nuts help with type 2 diabetes?

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

Similar autoantibody profiles in long COVID and fully recovered individuals

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

New analytical platform quantifies the structure of mRNA-based medicines

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

MicroRNAs associated with diabetes in human pancreatic islets

Could trained scent-detection dogs be used for chronic wasting disease surveillance?

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Bivalent booster recipients show slightly higher protection against infection and significantly higher protection against death than monovalent booster recipients

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Plasma D-dimer measurement can provide useful information when diagnosing periprosthetic joint infection

Smoking tobacco and vaping e-cigarettes may increase healthy young people's risk for severe COVID

Molecular switch regulates autophagy in plants

Review strengthens evidence that repetitive head impact exposure as chief risk factor for CTE

New method for capturing moments during protein translation

Casein-based diet found to protect diabetic mice against autoimmunity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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