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Study reveals unique norovirus characteristic of hiding from host immune system

Noroviruses are the leading cause of non-bacterial gastroenteritis in the world and are estimated to cause 267 million infections and 20,000 deaths each year. This virus causes severe diarrhea, nausea, and stomach pain.

11 Oct 2017

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Penn’s ITMAT 12th Annual International Symposium focuses on pain biology, aging, and brain disorders

The latest science in why pain afflicts people differently, precision medicine and brain disorders, and how the bat genome informs the study of human aging, among many other topics, will be covered at the University of Pennsylvania's Institute for Translational Medicine and Therapeutics' 12th Annual International Symposium.

9 Oct 2017

Rutgers scientist receives $2.4 million grant to reduce indoor tanning among young women

A five-year, $2.4 million grant from the National Cancer Institute awarded to Rutgers Cancer Institute of New Jersey behavioral scientist Jerod L. Stapleton, PhD, will support the development and testing of a novel behavioral intervention delivered through the social media site Facebook to reduce high-risk indoor tanning behaviors among young women.

9 Oct 2017

Study reveals advancement in preservation of certain type of medicines in adverse conditions

A recent study by biological engineers at the Johns Hopkins Applied Physics Laboratory in Laurel, Maryland, demonstrated a significant advancement in the preservation of particular types of medicines, known as protein expression systems, for field applications - enabling those medicines to be stored and reconstituted on site in adverse conditions.

9 Oct 2017

$Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus$

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

Proton pump inhibitors (PPIs)—medications commonly used to treat heartburn, acid reflux, and ulcers—have been linked with potentially serious side effects including a possible increased risk of bone fractures.

9 Oct 2017

Researchers find surprising differences in first-ever whole-brain map of inhibitory neurons

Researchers at Penn State College of Medicine have collaborated on the first-ever quantitative whole-brain map of inhibitory neurons in the mouse brain. These brain cells play a crucial role in regulating response to stimuli and have been widely implicated in many psychiatric conditions.

6 Oct 2017

New antifungal drug developed to help in treatment of invasive fungal infections

University of Liverpool researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis.

6 Oct 2017

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

Julia Oh, Ph.D., a Jackson Laboratory (JAX) assistant professor who explores the communities of microorganisms that live on the human skin, has received a special New Innovator Award of $2,835,000 from the National Institutes of Health (NIH) to explore how to develop engineered probiotic treatments for a variety of skin and infectious diseases.

5 Oct 2017

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

Following studies showing that cocaine influences the replication and transcription of HIV, a researcher at the George Washington University School of Medicine and Health Sciences was awarded more than $2.3 million from the National Institutes of Health to look deeper into the involved molecular mechanisms that allow this effect to happen.

5 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

Novel agents appear to halt growth and progression of Ewing sarcoma

When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress.

4 Oct 2017

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

The number of alterations detected in the DNA collected from blood samples (liquid biopsies) of cancer patients treated with immune checkpoint inhibitors was associated with response to the treatment.

3 Oct 2017

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Clarivate Analytics has recently included the following 16 eBooks for coverage in Book Citation Index. The Book Citation Index in Web of Science™ Core Collection connects a library's book collection to powerful new discovery tools, giving researchers the ability to quickly and easily identify and access the most relevant books.

30 Sep 2017

Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Novartis has joined forces with researchers from the University of California, Berkeley, to develop new technologies for the discovery of next-generation therapeutics, pursuing the vast number of disease targets in cancer and other illnesses that have eluded traditional small-molecule compounds and are considered "undruggable."

28 Sep 2017

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

Cohen Veterans Bioscience partners with OCC to establish the Brain Commons database

Cohen Veterans Bioscience today announced its partnership with the Open Commons Consortium to establish the Brain Commons – a one-of-a-kind cloud-hosted site for combining Big Data that will be critical for the understanding of brain conditions.

28 Sep 2017

Cellular messaging mechanism could lead to new way of treating disease

A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health.

27 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

New pig model for stroke could accelerate drug discovery process

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process.

26 Sep 2017

Therapeutics News and Research

Study reveals unique norovirus characteristic of hiding from host immune system

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Penn’s ITMAT 12th Annual International Symposium focuses on pain biology, aging, and brain disorders

Rutgers scientist receives $2.4 million grant to reduce indoor tanning among young women

Study reveals advancement in preservation of certain type of medicines in adverse conditions

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

Researchers find surprising differences in first-ever whole-brain map of inhibitory neurons

New antifungal drug developed to help in treatment of invasive fungal infections

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Novel agents appear to halt growth and progression of Ewing sarcoma

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cohen Veterans Bioscience partners with OCC to establish the Brain Commons database

Cellular messaging mechanism could lead to new way of treating disease

MIT study sheds light on flu viruses' rapid evolution

New pig model for stroke could accelerate drug discovery process

Next-generation therapeutics eBook eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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