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Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors still suffer acute graft-versus-host disease (GVHD).

6 Sep 2012

TSC and PTEN genes important in controlling blood precursor cells in Drosophila

UCLA stem cell scientists have shown that two common tumor suppressor genes, TSC and PTEN, are vital to regulating the stem cell-like precursor cells that create the blood supply in Drosophila, the common fruit fly.

6 Sep 2012

F-18-FDG PET/CT may easily predict disease-free survival for invasive ductal breast cancer patients

Disease-free survival for invasive ductal breast cancer (IDC) patients may be easier to predict with the help of F-18-fludeoxyglucose positron emission tomography (PET)/computed tomography (CT) scans, according to research published in the September issue of The Journal of Nuclear Medicine. New data show that high maximum standard uptake value (SUVmax) of F-18-FDG in the lymph nodes prior to treatment could be an independent indicator of disease recurrence.

6 Sep 2012

LIN28 protein can bind directly to thousands of messenger RNAs

A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which is implicated in pluripotency and reprogramming as well as in cancer and other diseases.

6 Sep 2012

Two UNC autism researchers receive $12.6 million in grants from ACE program

Two autism researchers in the University of North Carolina School of Medicine have each been awarded $12.6 million grants in the latest round of funding from the National Institutes of Health's Autism Centers of Excellence (ACE) research program.

6 Sep 2012

Roundup: Cancer drug cost equity bill sitting on Calif. Gov's desk; Mass. cost-containment law could harm provider credit ratings

Out-of-pocket costs for cancer drugs can vary dramatically depending on whether the medications are administered through pill form or intravenous infusion. Newer oral drugs, which can be taken at home and often have fewer side effects than older drugs, can cost patients thousands of dollars a month, while receiving chemotherapy through an IV in an infusion center typically amounts to a standard co-payment for an office visit.

6 Sep 2012

Exposure to household chemical may raise cardiac risk

Exposure to perfluorooctanoic acid may be associated with cardiovascular disease and peripheral arterial disease, say researchers.

5 Sep 2012

Unemployment barrier to antidiabetic medication adherence

People with diabetes are less likely to adhere to their oral antidiabetic medication if they are unemployed, report researchers.

5 Sep 2012

Etiologic work-up crucial after stroke

An elusive stroke etiology does not diminish the importance of a full work-up, say researchers.

5 Sep 2012

Delayed WM growth in siblings of childhood-onset schizophrenia patients

The unaffected adolescent siblings of patients with childhood-onset schizophrenia show reduced white matter growth rates compared with other adolescents, researchers report.

5 Sep 2012

BD I patients at high risk for sleep apnea

Around half of overweight patients with bipolar I disorder are at high risk for developing obstructive sleep apnea, US study results suggest.

5 Sep 2012

People with generalized anxiety disorder have weak brain connections

A new University of Wisconsin-Madison imaging study shows the brains of people with generalized anxiety disorder (GAD) have weaker connections between a brain structure that controls emotional response and the amygdala, which suggests the brain's "panic button" may stay on due to lack of regulation.

5 Sep 2012

Researchers discover two gene variants that raise risk of pediatric cancer neuroblastoma

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress.

5 Sep 2012

People need to protect themselves against West Nile virus

As this year's threat from the West Nile virus continues, one infectious diseases expert at the University of Alabama at Birmingham says a vaccine is not in our near future, so people need to protect themselves.

5 Sep 2012

NeuroSigma's external Trigeminal Nerve Stimulation system awarded CE Certification

NeuroSigma, Inc., a Los Angeles-based medical device company, announced today that it received CE Certification for its external Trigeminal Nerve Stimulation (eTNS) system, called the Monarch, for the adjunctive treatment of epilepsy and major depressive disorder, for adults and children 9 years and older.

5 Sep 2012

Eurofins MWG Operon acquires Illumina HiSeq 2500 and MiSeq sequencers

Eurofins MWG Operon, one of the pioneers and key providers of next generation sequencing (NGS), has added an Illumina HiSeq 2500 and an Illumina MiSeq sequencer to its fleet of NGS sequencers.

From Illumina, Inc. 5 Sep 2012

Study evaluates prognostic utility of novel biomarkers of cardiovascular stress

Critical Diagnostics announced today, Circulation, an American Heart Association Journal, released online the first study evaluating the power of ST2 to predict development of heart failure and other adverse outcomes in the general population titled, "Prognostic Utility of Novel Biomarkers of Cardiovascular Stress: The Framingham Heart Study".

5 Sep 2012

Children's asthma symptoms could be worse due to chaotic home environment

Parental problems and a chaotic home environment could be preventing children from taking their prescribed asthma medication.

5 Sep 2012

New strategy for outsmarting cancer through its own social intelligence

In the face of mounting evidence that cancer cells communicate, cooperate and even engage in collective decision-making, biophysicists and cancer researchers at Rice University, Tel Aviv University and Johns Hopkins University are suggesting a new strategy for outsmarting cancer through its own social intelligence.

5 Sep 2012

Regular Fanconi anemia cells aren't sensitive to resveratrol

Fanconi anemia is a recessive genetic disorder affecting 1 in 350,000 babies, which leaves cells unable to repair damaged DNA. This lack of repair puts Fanconi anemia patients at high risk for developing a variety of cancers, especially leukemias and head and neck cancer.

5 Sep 2012