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New drug data release set to power genetic research into cancer treatment

This week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and exploration which will power genetic research into cancer treatment worldwide.

26 Jul 2019

'Junk' DNA mutations highly significant in autism and stroke

Non-coding DNA, junk DNA, genetic dark matter – these are all names for the 98% of DNA that doesn’t directly code for proteins but is crucial in regulating protein synthesis. This is now the focus of a large new study published in the journal Nature Genetics.

25 Jul 2019

Research links inherited BRCA2 mutations with increased risk of childhood lymphoma

A report from St. Jude Children's Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents.

25 Jul 2019

New study reveals the world's top genomic rearrangement detection tools

Published in Nature Communications, the study is the largest of its kind and was led by Walter and Eliza Hall Institute computational biologists Professor Tony Papenfuss, Dr Daniel Cameron and Mr Leon Di Stefano.

25 Jul 2019

Sequencing data could be used to prevent lyme disease

Researchers have successfully sequenced the genome of the animal that could carry the bacteria causing Lyme disease.

25 Jul 2019

Researchers harness the pain-relieving properties of cannabis to develop new pain killers

The cannabis plant produces pain-relieving molecules that are 30x more effective than aspirin. Researchers are now working on a plant-based pain killer.

25 Jul 2019

Study identifies new mechanism that impacts HIV infection

A team of scientists led by Texas Biomed's Assistant Professor Smita Kulkarni, Ph.D. and Mary Carrington, Ph.D., at the Frederick National Laboratory for Cancer Research, published results of a study that pinpointed a long noncoding RNA molecule which influences a key receptor involved in HIV infection and progression of the disease.

25 Jul 2019

Common feature that makes cancer cells appear bloated could be their potential weak spot

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material.

23 Jul 2019

Intestinal microbes may affect course of amyotrophic lateral sclerosis

Researchers at the Weizmann Institute of Science have shown in mice that intestinal microbes, collectively termed the gut microbiome, may affect the course of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

22 Jul 2019

New technology helps develop more personalized treatments for patients with advanced cancers

Being able to identify targets for adoptive cell therapies is one of the first steps in developing personalized treatments for people with hard-to-treat cancers.

22 Jul 2019

Scientists confirm HIV theory by sequencing 53-year old tissue

Researchers have extracted a near-complete HIV-1 genome from the lymph node tissue of a man who has been embedded in wax since 1966.

22 Jul 2019

Chemists discover a whole new class of microbial recipes

Microbes are master chefs of the biomolecular world; collectively, they harbor the ability to produce a vast array of unknown substances, some of which may have therapeutic or other useful properties.

22 Jul 2019

Genetic similarities of deadly bone cancer between dogs and children revealed

A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a study published today by Tufts University and the Translational Genomics Research Institute, an affiliate of City of Hope.

21 Jul 2019

Study provides new insight into how changes in DNA methylation contribute to diseases

More than half of our genome consists of transposons, DNA sequences that are reminiscent of ancient, extinct viruses.

19 Jul 2019

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

National Institute of Health researchers have reported the largest genomic study of type 2 diabetes in sub-Saharan Africans, with data from more than 5,000 individuals from Nigeria, Ghana and Kenya.

19 Jul 2019

IDT partners with Washington University to increase access to new NGS technologies

As part of its commitment to advocate for the genomics age, Integrated DNA Technologies aims to lower the barriers to access the latest NGS technologies.

From Integrated DNA Technologies 19 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

New research could help design algae that produces fuels and cleanup chemicals

It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent of their genes from bacteria to cope with toxic metals and salt stress in hot springs, according to a study in the journal eLife.

18 Jul 2019

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model.

17 Jul 2019

Genome News and Research

New drug data release set to power genetic research into cancer treatment

'Junk' DNA mutations highly significant in autism and stroke

Research links inherited BRCA2 mutations with increased risk of childhood lymphoma

New study reveals the world's top genomic rearrangement detection tools

Sequencing data could be used to prevent lyme disease

Researchers harness the pain-relieving properties of cannabis to develop new pain killers

Study identifies new mechanism that impacts HIV infection

Common feature that makes cancer cells appear bloated could be their potential weak spot

Intestinal microbes may affect course of amyotrophic lateral sclerosis

New technology helps develop more personalized treatments for patients with advanced cancers

Scientists confirm HIV theory by sequencing 53-year old tissue

Chemists discover a whole new class of microbial recipes

Genetic similarities of deadly bone cancer between dogs and children revealed

Study provides new insight into how changes in DNA methylation contribute to diseases

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

IDT partners with Washington University to increase access to new NGS technologies

Group of genes linked to longer lifespan in fruit flies discovered

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

New research could help design algae that produces fuels and cleanup chemicals

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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