Hormone News and Research

RSS

A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer Inc. announced today that it has agreed with Merck & Co., Inc., known as MSD outside the United States and Canada ("Merck"), through two Merck subsidiaries, to explore the therapeutic potential of Merck's investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets.

5 Feb 2014

Researchers identify specific biomarkers of obesity and early-stage colon cancer

Obesity is a known risk factor for many cancers including colon cancer, yet the reasons behind the colon cancer link have often remained unclear.

5 Feb 2014

Findings expand treatment options for hormone-dependent breast cancer

According to the United States Centers for Disease Control and Prevention, breast cancer is the most common cancer in women. For patients whose breast cancers are hormone-dependent, current treatment focuses on using drugs that block estrogen (a type of hormone) from attaching to estrogen receptors on tumor cells to prevent the cells from growing and spreading.

5 Feb 2014

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause Society (NAMS).

5 Feb 2014

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

Pfizer Inc. today announced that the randomized Phase 2 trial [PALOMA-1] of palbociclib achieved its primary endpoint by demonstrating a statistically significant and clinically meaningful improvement in progression-free survival (PFS) for the combination of palbociclib and letrozole compared with letrozole alone in post-menopausal women with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or newly diagnosed metastatic breast cancer.

4 Feb 2014

Complex intervention successful in reducing C-sections and neonatal morbities, say researchers

In a study to be presented on Feb. 6 in an oral plenary session at 8 a.m. CST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting-, in New Orleans, researchers will report that Cesarean deliveries reviews and best practices implementation are effective to provide optimal care by an appropriate management of medical interventions, leading to a significant reduction of cesarean deliveries and neonatal morbidity.

4 Feb 2014

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE - angiotensin-converting enzyme - a naturally occurring protein found in tissues throughout the body.

4 Feb 2014

Findings may help doctors personalize preterm birth prevention treatments

New research findings may soon help doctors personalize preterm birth prevention treatments by identifying which women at higher risk for preterm birth will be helped by progesterone injections.

4 Feb 2014

High sodium intake correlates with fatness and inflammation in adolescents

Most adolescents consume as much salt as adults - some more than twice the recommended daily allowance - and that high sodium intake correlates with fatness and inflammation regardless of how many calories they consume, researchers report.

3 Feb 2014

African American youths who experienced discrimination during adolescence may develop chronic diseases

African American youth who report experiencing frequent discrimination during adolescence are at risk for developing heart disease, high blood pressure, diabetes, and stroke in later years, according to a new study.

3 Feb 2014

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression.

31 Jan 2014

New American Cancer Society report calls diagnosis of childhood cancer

A new report from the American Cancer Society outlines progress made and -more importantly-challenges that remain in fighting childhood cancer. The report estimates the number of new cancer cases and deaths for children and adolescents in the United States, summarizes the most recent and comprehensive data on cancer incidence, mortality, and survival, and outlines what is known and where answers are still needed for childhood cancers.

31 Jan 2014

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

According to the National Institute of Mental Health, over 18 percent of American adults suffer from anxiety disorders, characterized as excessive worry or tension that often leads to other physical symptoms. Previous studies of anxiety in the brain have focused on the amygdala, an area known to play a role in fear.

31 Jan 2014

More than 1/3 of women experience hot flashes for 10 years after menopause

A team of researchers from the Perelman School of Medicine at the University of Pennsylvania has found that moderate to severe hot flashes continue, on average, for nearly five years after menopause, and more than a third of women experience moderate/severe hot flashes for 10 years or more after menopause.

31 Jan 2014

Study points to gender-specific mechanisms of brain repair following oxygen deprivation

Physicians have long known that oxygen deprivation to the brain around the time of birth causes worse damage in boys than girls. Now a study by researchers from the Johns Hopkins Children’s Center conducted in mice reveals one possible reason behind this gender disparity and points to gender-specific mechanisms of brain repair following such injury.

31 Jan 2014

New study sheds light on the progression and management of ‘silent’ adrenal tumours

CT scans are increasingly performed for a variety of medical indications, including for general health screening, which is growing in popularity. An estimated 4% of CT scans will coincidentally uncover a tumour in the adrenal gland, with no associated clinical symptoms. However, until now, evidence on how to manage these ‘silent’ tumours has been lacking, despite the fact that the growing demand for CT scans is likely to lead to increasing numbers of detections.

30 Jan 2014

Study: Combination treatment more than halves mortality rates for prostate cancer

Combination treatment more than halves mortality rates for prostate cancer, reports Norwegian health journal Dagens Medisin.

30 Jan 2014

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

We've all heard about circadian rhythm, the roughly 24-hour oscillations of biological processes that occur in many living organisms. Yet for all its influence in many aspects of our lives - from sleep to immunity and, particularly, metabolism - relatively little is understood about the mammalian circadian rhythm and the interlocking processes that comprise this complex biological clock.

30 Jan 2014

Dormant prostate cancer cells within bone tissue can be reawakened to a cancerous state

Dormant prostate cancer cells in bone tissue can be reawakened to cause secondary tumours, according to new research published in Endocrine-Related Cancer. Targeting the wake-up call could prevent metastasis and improve prostate cancer survival rates.

29 Jan 2014

Research shows how emotional similarity reduces stress

Does giving a speech in public stress you out? Or writing a big presentation for your boss? What about skydiving? One way to cope, according to a new study from Sarah Townsend, assistant professor of management and organization at the USC Marshall School of Business, is to share your feelings with someone who is having a similar emotional reaction to the same scenario

29 Jan 2014

Hormone News and Research

Further Reading

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Researchers identify specific biomarkers of obesity and early-stage colon cancer

Findings expand treatment options for hormone-dependent breast cancer

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

Complex intervention successful in reducing C-sections and neonatal morbities, say researchers

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Findings may help doctors personalize preterm birth prevention treatments

High sodium intake correlates with fatness and inflammation in adolescents

African American youths who experienced discrimination during adolescence may develop chronic diseases

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

New American Cancer Society report calls diagnosis of childhood cancer

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

More than 1/3 of women experience hot flashes for 10 years after menopause

Study points to gender-specific mechanisms of brain repair following oxygen deprivation

New study sheds light on the progression and management of ‘silent’ adrenal tumours

Study: Combination treatment more than halves mortality rates for prostate cancer

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

Dormant prostate cancer cells within bone tissue can be reawakened to a cancerous state

Research shows how emotional similarity reduces stress

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News