Immune System News and Research

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Study offers insights into immune reactions in severe COVID-19

Researchers may have come one step closer toward understanding how the immune system contributes to severe COVID-19.

21 Aug 2020

Researchers find clues to successful immune response in the T cells of COVID-19 patients

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

21 Aug 2020

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

21 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

Newly discovered molecule can suppress a wide range of cancers

Scientists at Scripps Research have discovered a molecule that can activate a natural immune-boosting protein called STING.

21 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs.

20 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

FDA provides update on adverse events associated with breast implants

Today, the U.S. Food and Drug Administration is providing an update on adverse events reported to the Agency related to breast implants, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and systemic signs and symptoms referred to by patients as breast implant illness (BII), which some patients report after receiving breast implants.

20 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

Drug used in rheumatoid arthritis and cancer treatment improves survival in critically ill COVID-19 patients

Researchers at Hackensack Meridian Health, New Jersey's largest and most comprehensive health network, have utilized its statewide observational database of more than 5,000 hospitalized COVID-19 patients to show that a drug normally used in rheumatoid arthritis and cancer treatments, tocilizumab, improves hospital survival in critically-ill patients admitted to the intensive care unit (ICU).

20 Aug 2020

Cytokine storms may prevent the development of long-term immunity to SARS-CoV-2

Shiv Pillai, MD, PhD, investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

19 Aug 2020

Researchers identify drug that improves survival in critically ill COVID-19 patients

19 Aug 2020

Removing copper from blood can destroy deadliest cancers that are resistant to immunotherapy

Australian researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to immunotherapy using models of the disease.

19 Aug 2020

Centralized medical records repository can perform data analysis and visualization

More than a decade ago, electronic medical records were all the rage, promising to transform health care and help guide clinical decisions and public health response.

19 Aug 2020

Mathematical modeling helps researchers track and tackle COVID-19 pandemic

The Editor-in-Chief Vitaly Volpert of the Institut Camille Jordan, University ofLyon, France, reviews how the public's new favourite scientific discipline, mathematical modelling, is being used to track and tackle the COVID-19 pandemic.

19 Aug 2020

Study fills crucial knowledge gaps on myasthenia gravis

A study of 181 patients at 16 sites across the country who test negative for two antibodies long known to cause muscle-weakening myasthenia gravis, found that about 15% test positive for one of two newly discovered antibodies that also attack the point of communication between nerves and muscle.

19 Aug 2020

The world is 'nowhere near herd immunity,' WHO says

Now, the World Health Organization (WHO) says that the world is nowhere near the amount of coronavirus immunity needed to induce herd immunity, where enough people would develop the antibodies to stop the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Aug 2020

Immune System News and Research

Study offers insights into immune reactions in severe COVID-19

Researchers find clues to successful immune response in the T cells of COVID-19 patients

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

Newly discovered molecule can suppress a wide range of cancers

Using engineered off-the-shelf therapeutic T cells to fight cancer

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A metabolic enzyme shows great potential as target for immunotherapies

FDA provides update on adverse events associated with breast implants

Researchers develop vaccine for human herpesvirus 6B

Drug used in rheumatoid arthritis and cancer treatment improves survival in critically ill COVID-19 patients

Cytokine storms may prevent the development of long-term immunity to SARS-CoV-2

Researchers identify drug that improves survival in critically ill COVID-19 patients

Removing copper from blood can destroy deadliest cancers that are resistant to immunotherapy

Centralized medical records repository can perform data analysis and visualization

Mathematical modeling helps researchers track and tackle COVID-19 pandemic

Study fills crucial knowledge gaps on myasthenia gravis

The world is 'nowhere near herd immunity,' WHO says

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