Inflammation News and Research

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Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

A team of international scientists has recently identified a distinct set of proinflammatory mediators and metabolites associated with the fatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, they have established a link between gut microbiome alteration and hyper-inflammatory response in patients with severe COVID-19. The study is currently available on the bioRxiv* preprint server.

1 Nov 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Study uncovers unknown effects of COVID-19 virus on the immune system

COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections.

28 Oct 2021

Study offers hope for a new therapeutic option for patients with severe asthma

A new monoclonal antibody therapy shows promise in offering an alternative treatment for patients suffering from moderate-to-severe asthma. Research led by Michael E. Wechsler, MD, MMSc, director of the National Jewish Health Cohen Family Asthma Institute, found that itepekimab was safe and effective in a phase 2 trial published online today in the New England Journal of Medicine.

28 Oct 2021

COVID-19 and subacute neuropsychiatric symptoms in adolescents

A new paper discusses neurologic symptoms in children with COVID-19.

27 Oct 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers at the Medical University of South Carolina report in the Journal of Viral Hepatitis that the activity levels of the proteins involved in liver scarring, or cirrhosis, begin to decrease immediately after treatment for the hepatitis C virus (HCV), suggesting the possibility of early healing.

26 Oct 2021

Clinically significant cataract associated with greater mortality risk from vascular causes

Clinically significant cataract is associated with an increased risk of death from vascular causes, such as stroke and heart attack, suggests research published online in the British Journal of Ophthalmology.

26 Oct 2021

New computer-aided data tool could improve treatment for many diseases

Scientists from Queen's University Belfast have developed a computer-aided data tool that could improve treatment for a range of illnesses.

26 Oct 2021

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

The SARS-CoV-2 virus does not infect blood vessels, despite the high risk of blood clots to COVID-19 patients, University of Queensland researchers have found.

26 Oct 2021

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Systemic lupus erythematosus (SLE), commonly referred to as simply "lupus", is an autoimmune disorder where the body's immune system attacks healthy tissue.

26 Oct 2021

Fermented soy product suppresses airway inflammation in animal models of asthma

Bronchial asthma causes symptoms such as wheezing and cough due to chronic airway inflammation, but there is no fundamental treatment for it, leaving a desire for new prevention and treatment methods.

26 Oct 2021

Air pollution reduces sperm count by causing brain inflammation, mice study shows

Researchers have long known that air pollution can increase the risk of disorders such as obesity, diabetes, and fertility, but they did not know the exact mechanism for how it can lead to these health conditions.

25 Oct 2021

Study finds link between genes and amount of bacterial toxins in the blood

Lipopolysaccharide, a virulence factor produced by bacteria, is a toxin that can cause a systemic inflammation via the circulation. In a recently completed study, genetic markers were discovered which are associated with a heightened lipopolysaccharide level in the blood.

25 Oct 2021

Inflammation News and Research

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

Researchers decipher when and why T cells become non-responsive to immunotherapy

Study uncovers unknown effects of COVID-19 virus on the immune system

Study offers hope for a new therapeutic option for patients with severe asthma

COVID-19 and subacute neuropsychiatric symptoms in adolescents

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Clinically significant cataract associated with greater mortality risk from vascular causes

New computer-aided data tool could improve treatment for many diseases

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Fermented soy product suppresses airway inflammation in animal models of asthma

Air pollution reduces sperm count by causing brain inflammation, mice study shows

Study finds link between genes and amount of bacterial toxins in the blood

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

Role of SARS-CoV-2 infection biomarkers in HIV replication

Scientists show how cold could alleviate multiple sclerosis symptoms

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

Specific amino acid supplementation could prevent the development of dementia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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