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SUMO1 protein may treat and/or prevent heart failure

A promising new drug target for the treatment and prevention of heart failure has been discovered by researchers at Mount Sinai School of Medicine in New York, NY, US. The study was presented at the ESC Congress 2012 by principal investigator Professor Roger J. Hajjar, MD.

26 Aug 2012

Creighton University research to improve patient care and outcomes in CAD treatment

Since 1990, Creighton University School of Medicine professor and researcher Devendra K. Agrawal, Ph.D., has been awarded more than $20 million in research grants to study coronary artery heart disease. He is determined to eradicate the impact of this heart disease—the number one killer of men and women in the United States.

26 Aug 2012

Mexican-Americans with ancestral links have higher insulin resistance levels

Mexican-Americans with an ancestral link to Amerindian tribes were found to have higher insulin resistance levels, which is an indication of several chronic conditions such as type 2 diabetes, according to research by The University of Texas Health Science Center at Houston (UTHealth).

26 Aug 2012

Research roundup: Who do patients seek for primary care?; Treating kids with antipsychotics

n order to find out what kind of doctor patients were visiting for primary care service, researchers analyzed the frequency in which patients visited generalists and specialists in 1999 and 2007 by using a nationally representative sample of outpatient visits.

26 Aug 2012

Trevo Retriever effectively removes blood clots in patients with stroke

Every 40 seconds, someone in the United States has a stroke, usually caused when a clot blocks an artery that supplies blood to the brain. Now the results of two multicenter studies published online in The Lancet on August 26 are giving physicians new innovative tools proven to better remove these clots that block blood flow.

26 Aug 2012

MRC awards grant to design new drug for treatment of chronic pain

Scientists at the University of Liverpool and the Royal Liverpool University Hospital have been awarded -1.4 million to design a new drug for the treatment of chronic pain.

24 Aug 2012

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Seattle Genetics, Inc. today announced the initiation of a phase Ib clinical trial evaluating SGN-75 in combination with everolimus (Afinitor) for patients with advanced metastatic renal cell carcinoma (RCC).

24 Aug 2012

Concern over tattoo-related infections

More care should be taken to prevent infections associated with tattooing, suggest researchers who describe a series of tattoo-related Mycobacterium chelonae infections in the USA.

24 Aug 2012

HIV-like immunodeficiency observed in Asia

Researchers have discovered an adult-onset immunodeficiency syndrome with symptoms similar to those of advanced HIV in Thailand and Taiwan.

24 Aug 2012

Vigorous exercise associated with mental illness vulnerability

Contrary to expectations, engagement in vigorous exercise is positively associated with the incidence and prevalence of psychiatric disorders, particularly bipolar II disorder and alcohol dependence, US researchers report.

24 Aug 2012

Prescription drug monitoring systems alert abuse

Electronic prescription monitoring programs may significantly improve drug-abuse detection and could alert clinicians to “doctor shopping,” say researchers.

24 Aug 2012

State Senator honors UCLA lung transplant doctors during special ceremony

Dr. Abbas Ardehali, professor of cardiothoracic surgery and director of the UCLA Heart and Lung Transplant program, and Dr. David Ross, professor of pulmonology and medical director of the UCLA Lung Transplant program, were honored by State Senator Sharon Runner (R-Antelope Valley) during a special ceremony at the State Senate Chamber in Sacramento on Aug. 21.

24 Aug 2012

Dartmouth’s professor shares news of DAR-901 TB vaccine development

Tuberculosis (TB) is second only to HIV/AIDS as the greatest killer worldwide attributable to a single infectious agent, according to the World Health Organization (WHO). With 8.8 million cases in 2010 and 95 percent of TB deaths occurring in low- and middle-income countries, the disease continues to be a major public health problem in the developing world. In a July address to the International Union Against Tuberculosis and Lung Disease, Dartmouth's C. Fordham (Ford) von Reyn shared news of a promising vaccine in the works.

24 Aug 2012

Guidelines for parents to beat back-to-school bugs

School bells are beginning to sound again across the country, so it will only be a matter of time until every parent comes face-to-face with a child who wakes up with a cold, fever or upset stomach.

24 Aug 2012

McGill University experts to present at World Cancer Congress

The following list includes some of the McGill University experts who will be attending or presenting at the World Cancer Congress (WCC), the largest gathering of international leaders in the field of cancer, taking place in Montreal from August 27 to 30, 2012.

24 Aug 2012

ALDH enzyme marks melanoma stem cells

Cancer stem cells are defined by three abilities: differentiation, self-renewal and their ability to seed a tumor. These stem cells resist chemotherapy and many researchers posit their role in relapse. A University of Colorado Cancer Center study recently published in the journal Stem Cells, shows that melanoma cells with these abilities are marked by the enzyme ALDH, and imagines new therapies to target high-ALDH cells, potentially weeding the body of these most dangerous cancer creators.

24 Aug 2012

WHO releases 2012 verbal autopsy instrument

"In today's world, the majority of deaths go unregistered," but "the information that comes from accurate and complete records of deaths -- who died, and why -- constitutes a huge resource for evidence-based health planning and development," Peter Byass, a professor of global health at Umea University in Sweden and director of the Umea Centre for Global Health Research, writes in this post in the PLoS "Speaking of Medicine" blog.

24 Aug 2012

Cocoa and blood pressure: an interview with Dr Karin Ried

The compounds in cocoa responsible for blood pressure reduction are called flavanols or polyphenols. Flavanols are also found in green tea, dark berries or red wine.

24 Aug 2012

Religion not a barrier to HIV testing, treatment, study finds

"Preachers who promise divine healing have often been blamed for turning desperate HIV-positive people against their life-prolonging antiretroviral (ARV) medication and risking their health, but recent research suggests that religious beliefs may not be a barrier to treatment after all," IRIN/Plus News reports.

24 Aug 2012

Scientists develop reliable method to convert adult blood cells into iPSCs

Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body.

24 Aug 2012