Catalyst News and Research

RSS

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

Sleep fragmentation linked to migraine risk a day later

Nearly half of all patients who suffer migraines report sleep disturbance as a trigger for their headaches. But the relationship between sleep and migraine headaches is not well understood or well-studied.

16 Dec 2019

Precision epigenome editing can repair genetic syndrome of intellectual disability

Using a targeted gene epigenome editing approach in the developing mouse brain, Johns Hopkins Medicine researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, which causes intellectual disability and obesity in people.

13 Dec 2019

Jefferson hotspotting program uses team-based model to addresses hospital 'super utilizers'

The United States faces a crisis in providing complex care for high-need, high-cost individuals--people who often suffer economic, mental and physical challenges.

11 Dec 2019

SleepCogni to trial its ‘ground breaking’ behavioural treatment for insomnia

SleepCogni has announced it will trial its unique insomnia treatment, following a £575k interim fund raising round, which includes existing shareholders and a new Innovate UK biomedical catalyst award, bringing its total funding to £1.7m to date.

11 Dec 2019

Nanosize container can slip inside cells and deliver medicines, gene therapies

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size - even hefty ones attached to the gene-editing tool called CRISPR.

6 Dec 2019

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

House Speaker Nancy Pelosi's flagship proposal to curb prescription drug prices, the "Lower Drug Costs Now Act" - H.R. 3 - could come up for a vote in the chamber this month.

5 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

How to make holidays healthier and less stressful without falling victim to the holiday hustle

The holidays are meant to be a time of celebration and quality time with family and friends. However, when trying to manage our families and navigate all of the festivities, this season is often a catalyst for a lot of stress and anxiety.

27 Nov 2019

Study reveals novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these therapies.

26 Nov 2019

CooperVision receives FDA approval for innovative MiSight 1 day contact lens

CooperVision announced it has received U.S. Food and Drug Administration approval on Nov. 15, 2019 of its innovative MiSight 1 day contact lens.

22 Nov 2019

Sphingolipids associated with heart disease in African Americans with lupus

When it comes to cholesterol, we've come to accept a simple narrative. Our risk of heart disease is lower when we have more "good cholesterol," or high-density lipoproteins (HDL), and less "bad cholesterol," or low-density lipoproteins (LDL) and triglycerides.

21 Nov 2019

Using 'Trojan horses' to kill tumor cells from within

Using "Trojan horses" to combat cancer from within the tumor cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada, the Institute of Nanoscience of Aragon, the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.

19 Nov 2019

U.S. Army project may lead to new class of self-healing materials and therapeutics for soldiers

Synthetic biologists working on a U.S. Army project have developed a process that could lead to a new class of synthetic polymers that may create new high-performance materials and therapeutics for Soldiers.

18 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Natural light and outdoor views improve workers’ cognitive performance

New research from the Well Living Lab, a Delos™ and Mayo Clinic collaboration, shows that office areas with windows, which provide people with natural light and views of the outdoors, improve workers' cognitive performance and satisfaction with their office environment.

31 Oct 2019

Chemotherapy-induced senescent cells eat neighboring cells

A new study has found that chemotherapy-induced senescent cancer cells feed on other neighboring cells to enhance their survival.

30 Oct 2019

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

November is National Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it resistant to therapies that work better for other tumor types," explains Angela Alistar, MD, medical director of GI Oncology at Morristown Medical Center.

30 Oct 2019

Study explores distribution of new diabetes cases and specialist density in the U.S.

In the last five years, the landscape of type 2 diabetes treatment has changed dramatically. Two new classes of drugs -- SGLT2 inhibitors and GLP-1 receptor agonists -- have been shown to prevent some of the most serious diabetes complications, including heart and kidney conditions, in patients.

25 Oct 2019

Enhanced informatics tool could help better identify nonfatal opioid overdose cases in the ED

A team of researchers at the Medical University of South Carolina has been awarded $3.75 million by the National Center for Advancing Translational Sciences to enhance an existing informatics tool known as "informatics for integrating biology and the bedside" or I2B2.

24 Oct 2019