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How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Study demonstrates that glutathione (GSH) significantly reduces acetaldehyde levels, a key factor in hangovers, though subjective symptoms showed little difference between groups. Pharmacokinetic data indicate that GSH accelerates acetaldehyde clearance, providing potential relief from hangover symptoms.

29 Sep 2024

From patient to physician: EJ Beck's medical journey at NYU Langone Health

As a child, EJ Beck was treated for a rare pediatric thyroid cancer at NYU Langone Health. About 10 years after the scan that declared her cancer-free, Beck was accepted into her No. 1 choice for a medical school: NYU Grossman School of Medicine.

27 Sep 2024

A randomized trial of mexiletine and lamotrigine in adults with non-dystrophic myotonia

The study, published in Lancet Neurology, detailed the "head-to-head" trial implemented by the researchers to test two drugs, mexiletine and lamotrigine, on people with the condition.

27 Sep 2024

Insights into testosterone recovery after androgen deprivation therapy for prostate cancer

A study led by researchers from the UCLA Health Jonsson Comprehensive Cancer Center sheds light on testosterone recovery following androgen deprivation therapy (ADT) in men undergoing radiotherapy for prostate cancer, providing key insights for optimizing patient care.

26 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

A week of intense cycling may burn abdominal fat without major weight loss, study finds

A week of extreme cycling significantly decreased visceral adiposity in middle-aged cyclists, emphasizing the role of exercise in body composition management.

23 Sep 2024

Triptans better at relieving migraine pain than recently marketed and more expensive drugs

A meta-analysis reveals triptans as the most effective acute migraine treatments, highlighting the need for their inclusion in the WHO Essential Medicines List.

23 Sep 2024

Study offers insights into chronic fatigue syndrome and its resemblance to long COVID-19

The study, which will serve "as a guide for rapid diagnosis", provides valuable information for the medical community, in particular in primary care.

20 Sep 2024

Eat more fruit and vegetables to lower frailty risk

Research finds that higher intake of fruits and vegetables significantly lowers frailty risk, especially in underweight individuals. Whole fruits and red-orange vegetables offer the greatest protective effects.

19 Sep 2024

Drug breakthrough provides new hope for cancer patients with cachexia

Researchers discovered a drug that safely and effectively helped cancer patients when they suffered from cachexia (ku-KEK-see-uh), a common condition related to cancer that involves weight loss and muscle wasting.

19 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024

Long COVID patients maintain robust immune memory two years after infection

Researchers discovered that SARS-CoV-2-specific T and B cells in long COVID patients are maintained for two years, similar to fully recovered individuals, offering insights into long-term immunity.

17 Sep 2024

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the bladder.

17 Sep 2024

Study reveals high incidence of orthostatic intolerance in children with long COVID

A new study from Kennedy Krieger Institute shows that the majority of children diagnosed with long COVID are likely to experience orthostatic intolerance (OI), a condition that causes the body to struggle with regulating blood pressure and heart rate when standing up.

16 Sep 2024

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

16 Sep 2024

New data shows persistent struggles for endometriosis sufferers

The experience of living with endometriosis appears as frustrating and painful today as it was at the turn of the millennium, worrying new data shows.

16 Sep 2024

New drug shows strong activity against brain metastases in HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer.

13 Sep 2024

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden.

12 Sep 2024

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

12 Sep 2024

Fatigue News and Research

How viral persistence and immune dysfunction drive long COVID

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

From patient to physician: EJ Beck's medical journey at NYU Langone Health

A randomized trial of mexiletine and lamotrigine in adults with non-dystrophic myotonia

Insights into testosterone recovery after androgen deprivation therapy for prostate cancer

Researchers gain new understanding of how immune cells respond to heat during fever

A week of intense cycling may burn abdominal fat without major weight loss, study finds

Triptans better at relieving migraine pain than recently marketed and more expensive drugs

Study offers insights into chronic fatigue syndrome and its resemblance to long COVID-19

Eat more fruit and vegetables to lower frailty risk

Drug breakthrough provides new hope for cancer patients with cachexia

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

Long COVID patients maintain robust immune memory two years after infection

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Study reveals high incidence of orthostatic intolerance in children with long COVID

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

New data shows persistent struggles for endometriosis sufferers

New drug shows strong activity against brain metastases in HER2-positive breast cancer

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

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