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Vibrio cholerae acquires antiviral defenses through horizontal gene transfer

Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with antiviral immune systems.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

One letter DNA change switches sex development in mice

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice.

9 Apr 2026

Genetic variants may help explain who loses more weight and who gets side effects on GLP-1 drugs

A large 23andMe-based GWAS found that common variants in GLP1R and GIPR help explain why some people lose more weight or experience more nausea and vomiting on GLP-1 drugs. The findings suggest genetics may eventually help predict who responds best to semaglutide or tirzepatide and who is more likely to develop side effects.

9 Apr 2026

Study explains why current BET inhibitors fail in cancer treatment

For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations.

9 Apr 2026

Scientists find new genetic causes for diabetes in babies

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies.

9 Apr 2026

Fat-producing enzyme identified as key driver of damage in Parkinson’s disease

A fat-producing enzyme in brain cells may play a key role in driving damage in Parkinson's disease and could offer a new target for treatment, scientists at Nanyang Technological University, Singapore (NTU Singapore) have found.

9 Apr 2026

Yale researchers use zebrafish to find precision treatments for autism

In recent decades, the zebrafish has become one of the most valuable model organisms in scientific research.

8 Apr 2026

Study finds genetic basis for GLP-1 weight loss efficacy and side effects

23andMe Research Institute, a nonprofit medical research organization, announced the publication of a study that identifies genetic predictors for GLP-1 weight loss efficacy and side effects.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Climate shock effects persist for generations, fruit fly study shows

A new paper in Molecular Biology and Evolution, published by Oxford University Press, finds that changes in animal development induced by climate shock persist generations after the initial event.

8 Apr 2026

Gut microbiota regulates intestinal epithelial cell function and plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

7 Apr 2026

Study questions benefits of fish oil after mild brain injuries

A first-of-its-kind study led by the Medical University of South Carolina raises questions about the value of fish oil supplements for people with repetitive mild traumatic brain injuries.

7 Apr 2026

Base editing corrects genetic mutation responsible for severe form of inherited epilepsy

University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the underlying cause of a severe form of epilepsy in lab mice.

7 Apr 2026

Interpretable machine learning model advances analysis of complex genetic traits

A new study published in Genome Research presents an interpretable artificial intelligence framework that improves both the accuracy and transparency of genomic prediction, a key challenge in fields such as precision medicine, crop science, and animal breeding.

7 Apr 2026

New blood biomarker improves cancer risk detection in people with Lynch Syndrome

Researchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can help identify and characterize asymptomatic people with Lynch Syndrome (LS) who are more susceptible to developing cancer based on early immune detection signatures, allowing clinicians to stratify patients based on their personal risk level.

6 Apr 2026

New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026

AI helps researchers find antimicrobial peptides in Earth’s harshest habitats

Researchers built the Extreme Environment Microbiome Catalog from 78,213 genomes across global extreme habitats, revealing major taxonomic and biosynthetic novelty, including 32,715 representative species, nearly 4 billion non-redundant genes, and 163,693 biosynthetic gene clusters. They then used protein language models to identify 3,032 candidate non-toxic antimicrobial peptides, with 84 of 100 synthesized peptides showing antibacterial activity and low cytotoxicity in the 50 tested in mammalian cells.

6 Apr 2026

Large-scale exposome research shows how multiple factors influence disease risk

For decades, scientists have been carefully unraveling the role of genes in disease by examining how small variations in a person's genetic code can shape lifelong risk of developing common conditions such as cancer, diabetes, or heart disease.

6 Apr 2026