Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021

Immune cells present in tumors from head and neck cancer patients, study reports

A new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the major targets of immune checkpoint inhibitors are present in tumors from head and neck cancer patients.

2 Sep 2021

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

A new study by researchers at Winship Cancer Institute of Emory University finds that cancer-associated mutations originate in blood progenitor cells, leading to distinct changes in both cancer and non-cancer immune cells in Waldenstrom macroglobulinemia (WM), a type of non-Hodgkin lymphoma and its precursor IgM monoclonal gammopathy of undetermined significance (MGUS).

2 Sep 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

Study illuminates genetic understanding of aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

20 Aug 2021

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

17 Aug 2021

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

In a recent study published in Cancer Research, researchers from Fels Cancer Institute for Personalized Medicine at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center identified specific leukemia gene mutations and the mechanisms by which they regulate DNA repair and respond to PARP inhibitors.

13 Aug 2021

UC San Diego scientists develop new method to keep cultured cells healthy

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

12 Aug 2021

NYU Langone and Perlmutter Cancer Center expand lung cancer screening services to more locations

As part of its mission to bring high-quality healthcare services closer to patients, NYU Langone Health and Perlmutter Cancer Center have expanded the Lung Cancer Screening Program to more than a dozen additional locations throughout its network in Manhattan, Brooklyn, Queens, and on Long Island.

10 Aug 2021

Acclaimed Pacific Shores Medical Group joins City of Hope

City of Hope, a world-renowned cancer research and treatment center, today announced that acclaimed Pacific Shores Medical Group has joined City of Hope.

9 Aug 2021

Learn & Lounge helps AYA patients, survivors to connect with peers and get support

Young cancer patients face unique challenges. That's why the UC Davis Comprehensive Cancer Center started an Adolescent and Young Adult (AYA) Oncology Program in 2020.

6 Aug 2021

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Using circulating tumor DNA to identify patients at risk of urothelial cancer relapse after surgical resection could help improve post-surgery treatment.

6 Aug 2021

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Shuo Ma, MD, '00 PhD, associate professor of Medicine in the Division of Hematology and Oncology, was co-first author of the clinical trial published in Blood.

5 Aug 2021

Experimental drug combination extends survival in mice with lung cancer, study finds

A combination of experimental drugs increased the attack of immune cells on non-small cell lung cancer (NSCLC) to extend survival in mice, a new study found.

5 Aug 2021

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Researchers have just established a structural basis for two spike glycoprotein epitopes of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are restricted to human leukocyte antigen (HLA) A2 molecules. More specifically, they are involved in the presentation of antigenic peptides to specific T lymphocytes and recognized by public and private T cell receptors. The research is currently available on the bioRxiv* preprint server.

2 Aug 2021

Can platelet size predict severity and mortality in COVID-19?

The ongoing COVID-19 pandemic has baffled researchers with its propensity to cause symptoms of largely unpredictable severity in the affected individuals. An exciting new study reports on the potential predictive value of platelet size in this situation. COVID-19 patients with severe disease often develop clots in vital organs, which leads to further complications. It is known that platelet size is a good indicator of activation.

22 Jul 2021

New technology can pave the way for development of long-acting drugs

The technology, consisting of a designed variant of a natural occurring protein called super albumin, can pave the way for the development of long-acting drugs. This can have major implications for individuals suffering from hemophilia.

21 Jul 2021

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.

21 Jul 2021

Hematology News and Research

Further Reading

Research reveals a previously unknown role for a key transcription regulator linked to cancer

Scientists identify a critical checkpoint in transcription elongation

Immune cells present in tumors from head and neck cancer patients, study reports

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Study illuminates genetic understanding of aggressive childhood leukemias

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

UC San Diego scientists develop new method to keep cultured cells healthy

NYU Langone and Perlmutter Cancer Center expand lung cancer screening services to more locations

Acclaimed Pacific Shores Medical Group joins City of Hope

Learn & Lounge helps AYA patients, survivors to connect with peers and get support

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Experimental drug combination extends survival in mice with lung cancer, study finds

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Can platelet size predict severity and mortality in COVID-19?

New technology can pave the way for development of long-acting drugs

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo