Histology News and Research

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Patient age remains a controversial factor in predicting prognosis for patients with renal cell carcinoma

In this large population study led by Verhoest and colleagues from several European hospitals, the clinical parameters for four patient age groups were evaluated to determine the influence of age at diagnosis on tumor characteristics and outcomes for RCC.

18 Apr 2007

Testosterone replacement therapy appears to be safe - has little effect on the prostate gland

Preliminary research suggests that testosterone replacement therapy for men with low testosterone levels appears to have little effect on the prostate gland, contrary to some reports that this therapy may be harmful, according to a study in the November 15 issue of JAMA: The Journal of the American Medical Association.

14 Nov 2006

Bladder urothelium in PBS/IC shows distinct differences in keratin profiles

Research groups from the Netherlands and Denmark led by Pilar Laguna studied urothelial involvement in PBS/IC by characterizing the keratin phenotype of bladder urothelium in 18 patients with the disorder.

20 Aug 2006

Computer-aided detection essential in preventing breast cancer

Computer-aided detection improves breast cancers in both screening and diagnostic patients according to a recent study done by a private practice radiologist in Santa Barbara, CA.

2 Aug 2006

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

The use of orthotopic urinary diversion has gained increasing popularity in the past 20 years.

14 Jun 2006

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

The use of orthotopic urinary diversion has gained increasing popularity in the past 20 years.

18 May 2006

Renal cell carcinoma in the pediatric population

While the incidence of renal cell carcinoma (RCC) is rising, it remains a relatively uncommon malignancy in the pediatric population, where it represents only 2-6% of solid renal malignancies.

16 May 2006

MicroCT-based virtual histology

Utah and Texas researchers combined miniature medical CT scans with high-tech computer methods to produce detailed three-dimensional images of mouse embryos - an efficient new method to test the safety of medicines and learn how mutant genes cause birth defects or cancer.

8 May 2006

Selecting patients for breast conserving therapy: The importance of lobular histology

Invasive lobular carcinoma (ILC) of the breast can be treated with breast conserving surgery (BCT), as is invasive ductal carcinoma (IDC), without greater future risk of radical surgical treatment or additional surgeries, according to a new study.

8 May 2006

Significant changes in tumor growth can be detected through short interval follow-up

These growths may have important clinical implications in the management of patients, enabling early discontinuation of potentially toxic chemotherapy drugs.

4 May 2006

Remaining 80% of breast cancer genes may soon be discovered

We are closer to finding the missing 80% of breast cancer genes than ever before thanks to the success of the COSMIC database (Catalogue Of Somatic Mutations In Cancer) the 5th European Breast Cancer Conference (EBCC-5) was told today.

23 Mar 2006

Therapy for metastatic renal cell carcinoma remains inadequate

The recent FDA approvals of the tyrosine kinase inhibitors sorafenib and sunitinib based on their activity in metastatic renal cell carcinoma have excited the medical oncology community

9 Mar 2006

Race may play a role in whether a patient accepts surgical treatment for lung cancer

A study in the November issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), found that blacks with lung cancer declined surgery at a higher rate than whites

14 Nov 2005

Women show a better response to lung cancer therapy, resulting in better survival rates

However, in untreated patients, women also had a 21 percent decreased risk of death as compared with men, leading researchers to believe lung cancer in women has a different biologic behavior and natural history than in men.

3 Nov 2005

Protein involved in 'mad cow' disease

The journal Brain Research has recently published the results of research work by scientists from the University of Navarra.

18 Oct 2005

New findings on brain tumors called ependymomas

Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases, the researchers said.

17 Oct 2005

Long-term outcomes promising for patients with localized, low-grade prostate cancer

A study that includes 20 years of follow-up does not support aggressive treatment for localized, low-grade prostate cancer, with data indicating a small risk of progression of this grade of cancer, according to a study in the May 4 issue of JAMA.

3 May 2005

New drug to treat chronic hepatitis B

The U.S. Food and Drug Administration (FDA) has given approval for a new drug to treat the potentially life-threatening disease Chronic hepatitis B.

30 Mar 2005

Patients with Hepatitis C have a significant decrease in their health-related quality-of-life

Patients with Hepatitis C virus (HCV) have a significant decrease in their health-related quality-of-life (HRQOL), although treatment success can mitigate this negative effect.

28 Mar 2005

Diagnosis of prions in patients should utilize novel strategy, conformation-dependent immunoassay

A technique for detecting prions in tissue, developed in recent years by UCSF scientists, is significantly more sensitive than the diagnostic procedures currently used to detect the lethal particles in samples of brain tissue from patients, according to a study performed by a UCSF team.

22 Feb 2005

Histology News and Research

Patient age remains a controversial factor in predicting prognosis for patients with renal cell carcinoma

Testosterone replacement therapy appears to be safe - has little effect on the prostate gland

Bladder urothelium in PBS/IC shows distinct differences in keratin profiles

Computer-aided detection essential in preventing breast cancer

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

Renal cell carcinoma in the pediatric population

MicroCT-based virtual histology

Selecting patients for breast conserving therapy: The importance of lobular histology

Significant changes in tumor growth can be detected through short interval follow-up

Remaining 80% of breast cancer genes may soon be discovered

Therapy for metastatic renal cell carcinoma remains inadequate

Race may play a role in whether a patient accepts surgical treatment for lung cancer

Women show a better response to lung cancer therapy, resulting in better survival rates

Protein involved in 'mad cow' disease

New findings on brain tumors called ependymomas

Long-term outcomes promising for patients with localized, low-grade prostate cancer

New drug to treat chronic hepatitis B

Patients with Hepatitis C have a significant decrease in their health-related quality-of-life

Diagnosis of prions in patients should utilize novel strategy, conformation-dependent immunoassay

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