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Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease

Chronic liver disease (CLD) and its advanced stage, cirrhosis, represent a significant global health burden, with portal hypertension (PH) being a primary driver of disease progression and decompensation.

12 Nov 2025

Study clarifies how biliary atresia overlaps with multiple congenital syndromes

Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or transplantation in early infancy.

12 Nov 2025

Assessing health system preparedness for MASLD in the Middle East and North Africa

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents an escalating healthcare burden across the Middle East and North Africa (MENA) region; however, system-level preparedness remains largely undefined.

11 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Study finds reduced cortical choline levels in people with anxiety disorders

People with anxiety disorders have lower levels of choline in their brains, according to research from UC Davis Health.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Scientists have uncovered a surprising connection between sugar metabolism and alcohol addiction, identifying a potential new therapeutic target for treating alcohol-associated liver disease (ALD) and alcohol use disorder (AUD).

10 Nov 2025

Routine liquid biopsy testing could reduce late-stage cancer diagnoses

Routine screening is limited to only a few cancer types. New research indicates that routine liquid biopsy testing (multi-cancer early detection testing) could substantially reduce late-stage cancer diagnoses, allowing patients to receive treatment at earlier cancer stages, which are more likely to respond to interventions.

10 Nov 2025

Do dietary supplements really improve muscle health in non-athletes?

Dietary supplements can support muscle health, but their effectiveness varies. This review explores their role in physical activity and age-related muscle loss.

10 Nov 2025

Proactive cardiac CT scans may be useful to identify other health problems

Coronary artery calcium (CAC) CT scans are becoming a more commonly used tool to effectively determine a patient's future risk of heart disease and heart attack.

10 Nov 2025

Genetic and cellular mechanisms underlying steatotic liver disease

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), has emerged as the dominant cause of chronic liver disease worldwide, displacing viral hepatitis as the primary aetiology.

10 Nov 2025

Protein linked to cancer plays key role in wound healing

When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously wrong, from hard-to-treat cancers to severe inflammatory conditions.

7 Nov 2025

Study reveals trends and future projections of cancer mortality in China

Cancer remains the second leading cause of death in China, accounting for nearly one-quarter of all deaths nationwide. Rapid socioeconomic change, environmental exposure, and an aging population have intensified the burden of cancer across the country.

7 Nov 2025

Liver News and Research

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease

Study clarifies how biliary atresia overlaps with multiple congenital syndromes

Assessing health system preparedness for MASLD in the Middle East and North Africa

New data supports earlier use of evolocumab in high-risk diabetes

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

Study finds reduced cortical choline levels in people with anxiety disorders

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Routine liquid biopsy testing could reduce late-stage cancer diagnoses

Do dietary supplements really improve muscle health in non-athletes?

Proactive cardiac CT scans may be useful to identify other health problems

Genetic and cellular mechanisms underlying steatotic liver disease

Protein linked to cancer plays key role in wound healing

Study reveals trends and future projections of cancer mortality in China

How diet affects aging metabolism differently for men and women

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Galectin-3 found to drive crucial cell fusion in early placental development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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